JP2023545926A - プログラム死受容体１（ｐｄ－１）抗体とヒアルロニダーゼ変異体とそれらのフラグメントとの安定製剤およびその使用方法 - Google Patents

プログラム死受容体１（ｐｄ－１）抗体とヒアルロニダーゼ変異体とそれらのフラグメントとの安定製剤およびその使用方法 Download PDF

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JP2023545926A
JP2023545926A JP2023518480A JP2023518480A JP2023545926A JP 2023545926 A JP2023545926 A JP 2023545926A JP 2023518480 A JP2023518480 A JP 2023518480A JP 2023518480 A JP2023518480 A JP 2023518480A JP 2023545926 A JP2023545926 A JP 2023545926A
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cancer
formulation
fragment
antibody
variant
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クリシュナマチャリ，ヨギタ
ミッタル，サチン
サンガニ，サヒル・エス
フォレスト，ウィリアム・ピー・ジュニア
スー，ヨンチャオ
チャオ，シィ
スミス，ケイトリン・ジーン
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メルク・シャープ・アンド・ドーム・エルエルシー
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01035—Hyaluronoglucosaminidase (3.2.1.35), i.e. hyaluronidase
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    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01063—1,2-Alpha-L-fucosidase (3.2.1.63)
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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JP2023518480A 2020-09-24 2021-09-23 プログラム死受容体１（ｐｄ－１）抗体とヒアルロニダーゼ変異体とそれらのフラグメントとの安定製剤およびその使用方法 Pending JP2023545926A (ja)

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US202063082888P 2020-09-24 2020-09-24
US63/082,888 2020-09-24
PCT/US2021/051641 WO2022066832A1 (en) 2020-09-24 2021-09-23 Stable formulations of programmed death receptor 1 (pd-1) antibodies and hyaluronidase variants and fragments thereof and methods of use thereof

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JP2023545926A true JP2023545926A (ja) 2023-11-01
JP2023545926A5 JP2023545926A5 (https=) 2024-05-09

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EP (1) EP4217394A1 (https=)
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KR (1) KR20230074516A (https=)
CN (1) CN116472290A (https=)
AR (1) AR123585A1 (https=)
AU (1) AU2021347967B2 (https=)
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KR20230074516A (ko) 2023-05-30
CA3192509A1 (en) 2022-03-31
AU2021347967B2 (en) 2026-04-09
AR123585A1 (es) 2022-12-21
BR112023005377A2 (pt) 2023-04-25
EP4217394A1 (en) 2023-08-02
IL301533A (en) 2023-05-01
CO2023003576A2 (es) 2023-04-27
TW202227133A (zh) 2022-07-16
AU2021347967A1 (en) 2023-06-01
CN116472290A (zh) 2023-07-21
US20220089738A1 (en) 2022-03-24

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