JP2023545830A5 - - Google Patents
Info
- Publication number
- JP2023545830A5 JP2023545830A5 JP2023523244A JP2023523244A JP2023545830A5 JP 2023545830 A5 JP2023545830 A5 JP 2023545830A5 JP 2023523244 A JP2023523244 A JP 2023523244A JP 2023523244 A JP2023523244 A JP 2023523244A JP 2023545830 A5 JP2023545830 A5 JP 2023545830A5
- Authority
- JP
- Japan
- Prior art keywords
- therapeutic composition
- composition according
- raav
- insect cells
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063092179P | 2020-10-15 | 2020-10-15 | |
| US63/092,179 | 2020-10-15 | ||
| PCT/US2021/055243 WO2022082017A2 (en) | 2020-10-15 | 2021-10-15 | Recombinant adeno-associated virus compositions and methods for producing same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023545830A JP2023545830A (ja) | 2023-10-31 |
| JP2023545830A5 true JP2023545830A5 (https=) | 2024-10-24 |
Family
ID=78819612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023523244A Pending JP2023545830A (ja) | 2020-10-15 | 2021-10-15 | 組換えアデノ随伴ウイルス組成物及びその生産方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20220119843A1 (https=) |
| EP (1) | EP4229206A2 (https=) |
| JP (1) | JP2023545830A (https=) |
| KR (1) | KR20230088393A (https=) |
| CN (1) | CN116710567A (https=) |
| AU (1) | AU2021359852A1 (https=) |
| CA (1) | CA3198675A1 (https=) |
| IL (1) | IL302109A (https=) |
| MX (1) | MX2023004420A (https=) |
| WO (1) | WO2022082017A2 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4598940A1 (en) | 2022-10-04 | 2025-08-13 | Eli Lilly and Company | Gene therapy for trem2-associated diseases and disorders |
| AU2023375569A1 (en) | 2022-11-11 | 2025-05-29 | Eli Lilly And Company | Synthetic nucleic acids including astrocyte-directed promoter constructs and methods of using the same |
| CN116350801A (zh) * | 2022-11-22 | 2023-06-30 | 四川至善唯新生物科技有限公司 | 一种重组腺相关病毒载体的药物组合物及其用途 |
| TW202432839A (zh) * | 2022-12-06 | 2024-08-16 | 美商再生元醫藥公司 | 用於確定病毒載體基因體滴度之液滴式數位ｐｃｒ分析 |
| WO2025190864A1 (en) * | 2024-03-11 | 2025-09-18 | Sartorius Stedim Biotech Gmbh | Improved cell lysis methods, reagents, and kits for viral vector release and production |
| WO2026043765A1 (en) | 2024-08-21 | 2026-02-26 | Eli Lilly And Company | Engineered regulatory splice elements for gene therapies |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2573170T3 (en) | 2001-12-17 | 2018-04-09 | Univ Pennsylvania | Sequences of adeno-associated virus (AAV) serotype 9, vectors containing them, and their use |
| WO2007084773A2 (en) * | 2006-01-20 | 2007-07-26 | University Of North Carolina At Chapel Hill | Enhanced production of infectious parvovirus vectors in insect cells |
| EP3387138B1 (en) * | 2015-12-11 | 2022-01-26 | The Trustees Of The University Of Pennsylvania | Scalable purification method for aav9 |
| CN106916793B (zh) * | 2015-12-24 | 2019-01-15 | 中国科学院武汉物理与数学研究所 | 一种重组腺相关病毒的制备方法及重组杆状病毒 |
| US20200316221A1 (en) * | 2016-10-13 | 2020-10-08 | University Of Massachusetts | Aav capsid designs |
| CN112501208A (zh) | 2017-10-03 | 2021-03-16 | 普利维尔治疗公司 | 用于溶酶体障碍的基因疗法 |
| AU2018346104B2 (en) * | 2017-10-03 | 2023-07-27 | Prevail Therapeutics, Inc. | Gene therapies for lysosomal disorders |
| BR112020006661A2 (pt) * | 2017-10-03 | 2020-10-13 | Prevail Therapeutics, Inc. | terapias de genes para distúrbios lipossomais |
| BR112020008033A2 (pt) | 2017-10-23 | 2020-10-27 | Prevail Therapeutics, Inc. | terapias gênicas para doença neurodegenerativa |
| WO2019094253A1 (en) * | 2017-11-08 | 2019-05-16 | Avexis Inc. | Means and method for preparing viral vectors and uses of same |
-
2021
- 2021-10-15 MX MX2023004420A patent/MX2023004420A/es unknown
- 2021-10-15 AU AU2021359852A patent/AU2021359852A1/en active Pending
- 2021-10-15 CN CN202180078052.9A patent/CN116710567A/zh active Pending
- 2021-10-15 IL IL302109A patent/IL302109A/en unknown
- 2021-10-15 US US17/502,979 patent/US20220119843A1/en active Pending
- 2021-10-15 WO PCT/US2021/055243 patent/WO2022082017A2/en not_active Ceased
- 2021-10-15 CA CA3198675A patent/CA3198675A1/en active Pending
- 2021-10-15 EP EP21816205.5A patent/EP4229206A2/en active Pending
- 2021-10-15 JP JP2023523244A patent/JP2023545830A/ja active Pending
- 2021-10-15 KR KR1020237015788A patent/KR20230088393A/ko active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023545830A5 (https=) | ||
| JP7561788B2 (ja) | 臨床使用に適した無血清懸濁細胞培養システムにおいて組換えアデノ随伴ウイルス（ａａｖ）ベクターを産生するスケーラブルな方法 | |
| US6995006B2 (en) | Methods for generating high titer helper-free preparations of released recombinant AAV vectors | |
| US6566118B1 (en) | Methods for generating high titer helper-free preparations of released recombinant AAV vectors | |
| EP1009808B1 (en) | Methods for generating high titer helper-free preparations of recombinant aav vectors | |
| Qu et al. | Scalable downstream strategies for purification of recombinant adeno-associated virus vectors in light of the properties | |
| JP5268890B2 (ja) | Ａａｖの規模適応性の製造方法 | |
| US6593123B1 (en) | Large-scale recombinant adeno-associated virus (rAAV) production and purification | |
| JP7598333B2 (ja) | 組換えウイルスベクターの製造方法 | |
| JP2004508041A (ja) | 組換え型アデノ随伴ウイルス（ｒＡＡＶ）をパッケージングする親細胞、それらの生成方法、およびその使用 | |
| US20250059564A1 (en) | Viral vector constructs for delivery of nucleic acids encoding cytokines and uses thereof for treating cancer | |
| CN120513301A (zh) | 纯化完全重组aav颗粒的方法 | |
| JP2024542950A5 (https=) | ||
| WO2005035743A1 (en) | Method for large-scale production, isolation, purification and the uses of multi-type recombinant adeno-associated virus vectors | |
| JP2025522718A (ja) | 組み換えウイルスの改善された発酵産生のための方法及びキット | |
| US20250382587A1 (en) | Methods for manufacturing viruses and viral particles | |
| AU2003204921B2 (en) | Methods for generating high titer helper-free preparations of recombinant AAV vectors | |
| WO2025065890A1 (zh) | 一种重组腺相关病毒颗粒、重组腺相关病毒载体系统及其应用 | |
| WO2025238067A1 (en) | Novel vector system for aav production | |
| WO2026089607A1 (en) | Recombinant baculovirus with improved genetic stability | |
| CN117098841A (zh) | 用于纯化重组病毒颗粒的方法 | |
| AU2007205720A1 (en) | Methods for generating high titer helper-free preparations of recombinant AAV vectors |