CN116710567A - 重组腺相关病毒组合物及其产生方法 - Google Patents

重组腺相关病毒组合物及其产生方法 Download PDF

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CN116710567A
CN116710567A CN202180078052.9A CN202180078052A CN116710567A CN 116710567 A CN116710567 A CN 116710567A CN 202180078052 A CN202180078052 A CN 202180078052A CN 116710567 A CN116710567 A CN 116710567A
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therapeutic composition
raav
column
cell
buffer
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Chinese (zh)
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戴勇
周敬民
加勒特·丹尼尔斯
乔纳森·陈
豪尔赫·哈勒
斯图尔特·尼尔森
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Privelle Therapeutics
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Privelle Therapeutics
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CN202180078052.9A 2020-10-15 2021-10-15 重组腺相关病毒组合物及其产生方法 Pending CN116710567A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063092179P 2020-10-15 2020-10-15
US63/092,179 2020-10-15
PCT/US2021/055243 WO2022082017A2 (en) 2020-10-15 2021-10-15 Recombinant adeno-associated virus compositions and methods for producing same

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Publication Number Publication Date
CN116710567A true CN116710567A (zh) 2023-09-05

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CN202180078052.9A Pending CN116710567A (zh) 2020-10-15 2021-10-15 重组腺相关病毒组合物及其产生方法

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US (1) US20220119843A1 (https=)
EP (1) EP4229206A2 (https=)
JP (1) JP2023545830A (https=)
KR (1) KR20230088393A (https=)
CN (1) CN116710567A (https=)
AU (1) AU2021359852A1 (https=)
CA (1) CA3198675A1 (https=)
IL (1) IL302109A (https=)
MX (1) MX2023004420A (https=)
WO (1) WO2022082017A2 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4598940A1 (en) 2022-10-04 2025-08-13 Eli Lilly and Company Gene therapy for trem2-associated diseases and disorders
EP4615981A1 (en) 2022-11-11 2025-09-17 Eli Lilly and Company Synthetic nucleic acids including astrocyte-directed promoter constructs and methods of using the same
CN116350801A (zh) * 2022-11-22 2023-06-30 四川至善唯新生物科技有限公司 一种重组腺相关病毒载体的药物组合物及其用途
TW202432839A (zh) * 2022-12-06 2024-08-16 美商再生元醫藥公司 用於確定病毒載體基因體滴度之液滴式數位ｐｃｒ分析
WO2025190864A1 (en) * 2024-03-11 2025-09-18 Sartorius Stedim Biotech Gmbh Improved cell lysis methods, reagents, and kits for viral vector release and production
WO2026043765A1 (en) 2024-08-21 2026-02-26 Eli Lilly And Company Engineered regulatory splice elements for gene therapies

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002359284A1 (en) 2001-12-17 2003-06-30 The Trustees Of The University Of Pennsylvania Adeno-associated virus (aav) serotype 9 sequences, vectors containing same, and uses therefor
WO2007084773A2 (en) * 2006-01-20 2007-07-26 University Of North Carolina At Chapel Hill Enhanced production of infectious parvovirus vectors in insect cells
EP3387138B1 (en) * 2015-12-11 2022-01-26 The Trustees Of The University Of Pennsylvania Scalable purification method for aav9
CN106916793B (zh) * 2015-12-24 2019-01-15 中国科学院武汉物理与数学研究所 一种重组腺相关病毒的制备方法及重组杆状病毒
US20200316221A1 (en) * 2016-10-13 2020-10-08 University Of Massachusetts Aav capsid designs
EP3692075A4 (en) * 2017-10-03 2022-02-09 Prevail Therapeutics, Inc. GENE THERAPIES FOR LYSOSOMAL DISEASES
BR112020006671A2 (pt) 2017-10-03 2020-12-01 Prevail Therapeutics, Inc. terapias genéticas para distúrbios lisossômicos
KR102709597B1 (ko) * 2017-10-03 2024-09-26 프리베일 테라퓨틱스, 인크. 리소좀 장애를 위한 유전자 요법
AU2018354195A1 (en) 2017-10-23 2020-06-04 Prevail Therapeutics, Inc. Gene therapies for neurodegenerative disease
MX2020004830A (es) * 2017-11-08 2020-11-11 Avexis Inc Medios y metodo para preparar vectores virales y usos de los mismos.

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Publication number Publication date
US20220119843A1 (en) 2022-04-21
AU2021359852A9 (en) 2025-03-27
IL302109A (en) 2023-06-01
WO2022082017A3 (en) 2022-07-21
JP2023545830A (ja) 2023-10-31
WO2022082017A9 (en) 2022-10-13
MX2023004420A (es) 2023-07-05
KR20230088393A (ko) 2023-06-19
WO2022082017A2 (en) 2022-04-21
AU2021359852A1 (en) 2023-06-08
CA3198675A1 (en) 2022-04-21
EP4229206A2 (en) 2023-08-23

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