|
US4501729A
(en)
|
1982-12-13 |
1985-02-26 |
Research Corporation |
Aerosolized amiloride treatment of retained pulmonary secretions
|
|
US5366894A
(en)
|
1986-06-30 |
1994-11-22 |
Pharmaceutical Proteins Limited |
Peptide production
|
|
US5175385A
(en)
|
1987-09-03 |
1992-12-29 |
Ohio University/Edison Animal Biotechnolgy Center |
Virus-resistant transgenic mice
|
|
US5175384A
(en)
|
1988-12-05 |
1992-12-29 |
Genpharm International |
Transgenic mice depleted in mature t-cells and methods for making transgenic mice
|
|
US5194376A
(en)
|
1989-02-28 |
1993-03-16 |
University Of Ottawa |
Baculovirus expression system capable of producing foreign gene proteins at high levels
|
|
US5478745A
(en)
|
1992-12-04 |
1995-12-26 |
University Of Pittsburgh |
Recombinant viral vector system
|
|
WO1994018834A1
(en)
|
1993-02-16 |
1994-09-01 |
Virginia Tech Intellectual Properties, Inc. |
Polyelectrolyte dna conjugation and genetic transformation of an animal
|
|
PT733103E
(pt)
|
1993-11-09 |
2004-07-30 |
Targeted Genetics Corp |
Criacao de elevados titulos de vectores de aav recombinantes
|
|
US5872005A
(en)
|
1994-11-03 |
1999-02-16 |
Cell Genesys Inc. |
Packaging cell lines for adeno-associated viral vectors
|
|
US6093570A
(en)
|
1995-06-07 |
2000-07-25 |
The University Of North Carolina At Chapel Hill |
Helper virus-free AAV production
|
|
US6040183A
(en)
|
1995-06-07 |
2000-03-21 |
University Of North Carloina At Chapel Hill |
Helper virus-free AAV production
|
|
US5622856A
(en)
|
1995-08-03 |
1997-04-22 |
Avigen |
High efficiency helper system for AAV vector production
|
|
EP1983057A3
(en)
|
1995-09-08 |
2009-01-07 |
Genzyme Corporation |
Improved AAV vectors for gene therapy
|
|
DE19608753C1
(de)
|
1996-03-06 |
1997-06-26 |
Medigene Gmbh |
Transduktionssystem und seine Verwendung
|
|
US6521225B1
(en)
|
1996-09-06 |
2003-02-18 |
Chiron Corporation |
AAV vectors
|
|
US7732129B1
(en)
|
1998-12-01 |
2010-06-08 |
Crucell Holland B.V. |
Method for the production and purification of adenoviral vectors
|
|
ES2278399T3
(es)
|
1996-11-20 |
2007-08-01 |
Introgen Therapeutics, Inc. |
Metodo mejorado para la produccion y purificacion de vectores adenovirales.
|
|
FR2756297B1
(fr)
|
1996-11-22 |
1999-01-08 |
Centre Nat Rech Scient |
Procede de production de virus recombinants
|
|
US6207455B1
(en)
|
1997-05-01 |
2001-03-27 |
Lung-Ji Chang |
Lentiviral vectors
|
|
US6156303A
(en)
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
|
US6995006B2
(en)
|
1997-09-05 |
2006-02-07 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
|
CA2303768C
(en)
|
1997-09-19 |
2009-11-24 |
The Trustees Of The University Of Pennsylvania |
Methods and vector constructs useful for production of recombinant aav
|
|
CA2304983A1
(en)
|
1997-09-24 |
1999-04-01 |
The Regents Of The University Of California |
Non-primate lentiviral vectors and packaging systems
|
|
US5994136A
(en)
|
1997-12-12 |
1999-11-30 |
Cell Genesys, Inc. |
Method and means for producing high titer, safe, recombinant lentivirus vectors
|
|
EP0924298A1
(en)
|
1997-12-18 |
1999-06-23 |
Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) |
Protein expression in baculovirus vector expression systems
|
|
CA2321261A1
(en)
|
1998-03-04 |
1999-09-10 |
Onyx Pharmaceuticals, Inc. |
Baculovirus expression system and method for high throughput expression of genetic material
|
|
US20030017138A1
(en)
|
1998-07-08 |
2003-01-23 |
Menzo Havenga |
Chimeric adenoviruses
|
|
AU774706B2
(en)
|
1998-09-22 |
2004-07-08 |
Johns Hopkins University, The |
Methods for large-scale production of recombinant AAV vectors
|
|
ES2340230T3
(es)
|
1998-11-10 |
2010-05-31 |
University Of North Carolina At Chapel Hill |
Vectores viricos y sus procedimientos de preparacion y administracion.
|
|
US7262049B2
(en)
|
1999-03-16 |
2007-08-28 |
Dana-Farber Cancer Institute, Inc. |
Pseudotyped lentiviral vectors and uses thereof
|
|
ATE519855T1
(de)
|
1999-05-17 |
2011-08-15 |
Crucell Holland Bv |
Rekombinantes adenovirus des serotyps ad11
|
|
ATE449858T1
(de)
|
1999-10-11 |
2009-12-15 |
Pasteur Institut |
Lentivirale vektoren für die herstellung von immunotherapeutischen zusammensetzungen
|
|
NZ522840A
(en)
|
2000-06-01 |
2004-12-24 |
Univ North Carolina |
A parvovirus vector that carries a duplexed genome resulting in co-packaging of strands of plus and minus polarity tethered together
|
|
US7201898B2
(en)
|
2000-06-01 |
2007-04-10 |
The University Of North Carolina At Chapel Hill |
Methods and compounds for controlled release of recombinant parvovirus vectors
|
|
GB0024550D0
(https=)
|
2000-10-06 |
2000-11-22 |
Oxford Biomedica Ltd |
|
|
US7749492B2
(en)
|
2001-01-05 |
2010-07-06 |
Nationwide Children's Hospital, Inc. |
AAV vectors and methods
|
|
EP1438075A4
(en)
|
2001-10-02 |
2006-04-19 |
Inst Clayton De La Rech |
METHOD AND COMPOSITIONS ASSOCIATED WITH LENTIVIRAL VECTORS WITH LIMITED EXPRESSION AND ITS APPLICATIONS
|
|
GB0130228D0
(en)
|
2001-12-18 |
2002-02-06 |
Hansa Medica Ab |
Protein
|
|
KR101021387B1
(ko)
|
2002-04-25 |
2011-03-14 |
크루셀 홀란드 비.브이. |
아데노바이러스 벡터를 생산하기 위한 수단 및 방법
|
|
EP1486567A1
(en)
|
2003-06-11 |
2004-12-15 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Improved adeno-associated virus (AAV) vector for gene therapy
|
|
US7427396B2
(en)
|
2004-06-03 |
2008-09-23 |
Genzyme Corporation |
AAV vectors for gene delivery to the lung
|
|
EP1828390B1
(en)
|
2004-12-15 |
2012-06-13 |
The University Of North Carolina At Chapel Hill |
Chimeric vectors
|
|
JP5427409B2
(ja)
|
2005-06-09 |
2014-02-26 |
ハンサ メディカル アクチボラゲット |
自己免疫疾患及び移植片拒絶反応を治療するためのＩｄｅＳプロテイナーゼ（化膿連鎖球菌由来）の使用
|
|
US7632509B2
(en)
|
2005-07-19 |
2009-12-15 |
Biosante Pharmaceuticals, Inc. |
Methods to express recombinant proteins from lentiviral vectors
|
|
EP2018421B1
(en)
|
2006-04-28 |
2012-12-19 |
The Trustees of the University of Pennsylvania |
Scalable production method for aav
|
|
GB0624874D0
(en)
|
2006-12-13 |
2007-01-24 |
Hansa Medical Ab |
Treatment
|
|
CN102584989B
(zh)
|
2007-09-14 |
2015-05-13 |
季诺维斯公司 |
用于解离Fcgamma-受体-IgG复合物及纯化与检测IgG的方法和试剂盒
|
|
WO2009075815A1
(en)
|
2007-12-07 |
2009-06-18 |
Duke University |
Immunomodulating gene therapy
|
|
CN102203242B
(zh)
|
2008-11-03 |
2013-06-12 |
克鲁塞尔荷兰公司 |
产生腺病毒载体的方法
|
|
GB0821100D0
(en)
|
2008-11-18 |
2008-12-24 |
Hansa Medical Ab |
Antibodies
|
|
CA2788682C
(en)
|
2010-02-05 |
2019-03-05 |
The University Of North Carolina At Chapel Hill |
Compositions and methods for enhanced parvovirus transduction
|
|
WO2011139379A2
(en)
|
2010-05-06 |
2011-11-10 |
Duke University |
A method of treating patients undergoing protein replacement therapy, gene replacement therapy, or other therapeutic modalities
|
|
ES2685611T3
(es)
|
2011-02-14 |
2018-10-10 |
The Children's Hospital Of Philadelphia |
Vector VAA8 mejorado con una actividad funcional aumentada y métodos de utilización del mismo
|
|
GB201103780D0
(en)
|
2011-03-04 |
2011-04-20 |
Hansa Medical Ab |
Treatment for ige-mediated disease
|
|
US9441206B2
(en)
|
2011-10-28 |
2016-09-13 |
The University Of North Carolina At Chapel Hill |
Cell line for production of adeno-associated virus
|
|
US9447433B2
(en)
|
2013-03-15 |
2016-09-20 |
The University Of North Carolina At Chapel Hill |
Synthetic adeno-associated virus inverted terminal repeats
|
|
ES2744565T3
(es)
|
2014-04-25 |
2020-02-25 |
Genethon |
Tratamiento de la hiperbilirrubinemia
|
|
WO2015191508A1
(en)
|
2014-06-09 |
2015-12-17 |
Voyager Therapeutics, Inc. |
Chimeric capsids
|
|
GB201413240D0
(en)
|
2014-07-25 |
2014-09-10 |
Hansa Medical Ab |
Method
|
|
KR102554850B1
(ko)
*
|
2015-02-06 |
2023-07-13 |
더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 |
최적화된 인간 응고 인자 viii 유전자 발현 카세트 및 그의 용도
|
|
GB201502305D0
(en)
|
2015-02-12 |
2015-04-01 |
Hansa Medical Ab |
Protein
|
|
GB201502306D0
(en)
|
2015-02-12 |
2015-04-01 |
Hansa Medical Ab |
Protein
|
|
EP3262065B1
(en)
*
|
2015-02-27 |
2024-04-03 |
The Charlotte-Mecklenburg Hospital Authority D/B/A Carolinas Healthcare System |
Methods and compositions for treating dystroglycanopathy disorders
|
|
EP4659816A3
(en)
|
2015-12-14 |
2025-12-31 |
The University of North Carolina at Chapel Hill |
MODIFIED CAPSID PROTEINS FOR IMPROVED PARVOVIRUS VECTOR DELIVERY
|
|
ES2877754T3
(es)
|
2016-02-04 |
2021-11-17 |
Genovis Ab |
Nuevas proteasas estreptocócicas
|
|
CA2971303C
(en)
*
|
2016-06-21 |
2026-03-03 |
Bamboo Therapeutics, Inc. |
Optimized mini-dystrophin genes and expression cassettes and their use
|
|
MX2019002842A
(es)
|
2016-09-12 |
2019-08-29 |
Genethon |
Variantes de alfa-glucosidasa acida y usos de las mismas.
|
|
WO2018093868A1
(en)
|
2016-11-16 |
2018-05-24 |
University Of Florida Research Foundation, Inc. |
Immunoglobulin proteases, compositions, and uses thereof
|
|
US10550405B2
(en)
|
2017-03-15 |
2020-02-04 |
The University Of North Carolina At Chapel Hill |
Rational polyploid adeno-associated virus vectors and methods of making and using the same
|
|
EP3648783B1
(en)
*
|
2017-07-07 |
2024-09-04 |
Genethon |
Novel polynucleotides encoding a human fkrp protein
|
|
US20210228738A1
(en)
|
2017-07-17 |
2021-07-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins
|
|
US10878588B2
(en)
|
2018-06-22 |
2020-12-29 |
X Development Llc |
Detection and replacement of transient obstructions from high elevation digital images
|
|
CN114521143B
(zh)
*
|
2019-09-19 |
2025-03-14 |
吉尼松公司 |
减轻fkrp心脏毒性的基因治疗表达系统
|