|
US5139941A
(en)
|
1985-10-31 |
1992-08-18 |
University Of Florida Research Foundation, Inc. |
AAV transduction vectors
|
|
US5436146A
(en)
|
1989-09-07 |
1995-07-25 |
The Trustees Of Princeton University |
Helper-free stocks of recombinant adeno-associated virus vectors
|
|
US6268213B1
(en)
|
1992-06-03 |
2001-07-31 |
Richard Jude Samulski |
Adeno-associated virus vector and cis-acting regulatory and promoter elements capable of expressing at least one gene and method of using same for gene therapy
|
|
US5869305A
(en)
|
1992-12-04 |
1999-02-09 |
The University Of Pittsburgh |
Recombinant viral vector system
|
|
US6204059B1
(en)
|
1994-06-30 |
2001-03-20 |
University Of Pittsburgh |
AAV capsid vehicles for molecular transfer
|
|
US5741683A
(en)
|
1995-06-07 |
1998-04-21 |
The Research Foundation Of State University Of New York |
In vitro packaging of adeno-associated virus DNA
|
|
US6093570A
(en)
|
1995-06-07 |
2000-07-25 |
The University Of North Carolina At Chapel Hill |
Helper virus-free AAV production
|
|
WO1998046728A1
(en)
|
1997-04-14 |
1998-10-22 |
Cell Genesys, Inc. |
Methods for increasing the efficiency of recombinant aav product
|
|
WO1999061643A1
(en)
|
1998-05-27 |
1999-12-02 |
University Of Florida |
Method of preparing recombinant adeno-associated virus compositions by using an iodixananol gradient
|
|
US6759237B1
(en)
|
1998-11-05 |
2004-07-06 |
The Trustees Of The University Of Pennsylvania |
Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same
|
|
CA2349838C
(en)
|
1998-11-05 |
2011-06-07 |
The Trustees Of The University Of Pennsylvania |
Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same
|
|
ES2340230T3
(es)
|
1998-11-10 |
2010-05-31 |
University Of North Carolina At Chapel Hill |
Vectores viricos y sus procedimientos de preparacion y administracion.
|
|
US7201898B2
(en)
|
2000-06-01 |
2007-04-10 |
The University Of North Carolina At Chapel Hill |
Methods and compounds for controlled release of recombinant parvovirus vectors
|
|
NZ532635A
(en)
|
2001-11-13 |
2007-05-31 |
Univ Pennsylvania |
A method of identifying unknown adeno-associated virus (AAV) sequences and a kit for the method
|
|
AU2003274397A1
(en)
|
2002-06-05 |
2003-12-22 |
University Of Florida |
Production of pseudotyped recombinant aav virions
|
|
CN1856576B
(zh)
|
2003-09-30 |
2011-05-04 |
宾夕法尼亚州立大学托管会 |
腺伴随病毒(aav)进化支、序列、含有这些序列的载体及它们的应用
|
|
WO2006110689A2
(en)
|
2005-04-07 |
2006-10-19 |
The Trustees Of The University Of Pennsylvania |
Method of increasing the function of an aav vector
|
|
US7588772B2
(en)
|
2006-03-30 |
2009-09-15 |
Board Of Trustees Of The Leland Stamford Junior University |
AAV capsid library and AAV capsid proteins
|
|
CA2653974A1
(en)
|
2006-05-30 |
2008-02-14 |
Mayo Foundation For Medical Education And Research |
Detecting and treating dementia
|
|
WO2007146046A2
(en)
|
2006-06-07 |
2007-12-21 |
Genzyme Corporation |
Gene therapy for amyotrophic lateral sclerosis and other spinal cord disorders
|
|
WO2009089635A1
(en)
|
2008-01-16 |
2009-07-23 |
Neurodyn, Inc. |
Treating neurodegenerative diseases with progranulin (pgrn)
|
|
JP5879256B2
(ja)
|
2009-05-02 |
2016-03-08 |
ジェンザイム・コーポレーション |
神経変性障害のための遺伝子治療
|
|
US20110203007A1
(en)
|
2010-02-16 |
2011-08-18 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Assays of neurodegenerative disorders, including frontotemporal dementia and amyotrophic lateral sclerosis
|
|
US9315825B2
(en)
|
2010-03-29 |
2016-04-19 |
The Trustees Of The University Of Pennsylvania |
Pharmacologically induced transgene ablation system
|
|
US20130023033A1
(en)
|
2010-03-29 |
2013-01-24 |
The Trustees Of The University Of Pennsylvania |
Pharmacologically induced transgene ablation system
|
|
US20150352185A1
(en)
|
2010-11-16 |
2015-12-10 |
Denis G. Kay |
Method for increasing neprilysin expression and activity
|
|
FR2977562B1
(fr)
|
2011-07-06 |
2016-12-23 |
Gaztransport Et Technigaz |
Cuve etanche et thermiquement isolante integree dans une structure porteuse
|
|
WO2015164723A1
(en)
*
|
2014-04-25 |
2015-10-29 |
The Trustees Of The University Of Pennsylvania |
Methods and compositions for treating metastatic breast cancer and other cancers in the brain
|
|
TN2017000353A1
(en)
*
|
2015-02-10 |
2019-01-16 |
Genzyme Corp |
Enhanced delivery of viral particles to the striatum and cortex
|
|
WO2017075338A2
(en)
*
|
2015-10-29 |
2017-05-04 |
Voyager Therapeutics, Inc. |
Delivery of central nervous system targeting polynucleotides
|
|
US20190060359A1
(en)
|
2015-11-02 |
2019-02-28 |
Neuraltus Pharmaceuticals, Inc. |
Treatment of neurodegenerative disease with sodium chlorite
|
|
WO2017100676A1
(en)
|
2015-12-11 |
2017-06-15 |
The Trustees Of The University Of Pennsylvania |
Scalable purification method for aav8
|
|
US11015173B2
(en)
|
2015-12-11 |
2021-05-25 |
The Trustees Of The University Of Pennsylvania |
Scalable purification method for AAV1
|
|
US11028372B2
(en)
|
2015-12-11 |
2021-06-08 |
The Trustees Of The University Of Pennsylvania |
Scalable purification method for AAVRH10
|
|
EP3387138B1
(en)
|
2015-12-11 |
2022-01-26 |
The Trustees Of The University Of Pennsylvania |
Scalable purification method for aav9
|
|
EP3411488A1
(en)
|
2016-02-03 |
2018-12-12 |
The Trustees Of The University Of Pennsylvania |
Gene therapy for treating mucopolysaccharidosis type i
|
|
WO2017151884A1
(en)
*
|
2016-03-02 |
2017-09-08 |
The Children's Hospital Of Philadelphia |
Therapy for frontotemporal dementia
|
|
US20210284701A1
(en)
|
2016-07-14 |
2021-09-16 |
Emory University |
Granulin Compositions and Uses Related Thereto
|
|
WO2018045347A1
(en)
|
2016-09-02 |
2018-03-08 |
Spark Therapeutics, Inc. |
Methods and vectors for treating cns disorders
|
|
JP7455579B2
(ja)
|
2017-02-28 |
2024-03-26 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
新規アデノ随伴ウイルス(aav)クレードfベクター及びその用途
|
|
KR102709597B1
(ko)
|
2017-10-03 |
2024-09-26 |
프리베일 테라퓨틱스, 인크. |
리소좀 장애를 위한 유전자 요법
|
|
BR112020006671A2
(pt)
|
2017-10-03 |
2020-12-01 |
Prevail Therapeutics, Inc. |
terapias genéticas para distúrbios lisossômicos
|
|
US20200283800A1
(en)
|
2017-10-23 |
2020-09-10 |
Prevail Therapeutics, Inc. |
Gene therapies for neurodegenerative diseases
|
|
US20220111005A1
(en)
|
2019-02-01 |
2022-04-14 |
Avrobio, Inc. |
Compositions and methods for treating neurocognitive disorders
|
|
BR112021015817A2
(pt)
|
2019-02-22 |
2021-10-13 |
The Trustees Of The University Of Pennsylvania |
Vírus adeno-associado recombinante para tratamento de neurodegeneração com início na idade adulta associado a grn
|
|
EP4204014A1
(en)
|
2020-08-26 |
2023-07-05 |
The Trustees of The University of Pennsylvania |
Recombinant adeno-associated virus for treatment of grn-associated adult-onset neurodegeneration
|