JP2023545359A5 - - Google Patents

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Publication number
JP2023545359A5
JP2023545359A5 JP2023515569A JP2023515569A JP2023545359A5 JP 2023545359 A5 JP2023545359 A5 JP 2023545359A5 JP 2023515569 A JP2023515569 A JP 2023515569A JP 2023515569 A JP2023515569 A JP 2023515569A JP 2023545359 A5 JP2023545359 A5 JP 2023545359A5
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JP
Japan
Prior art keywords
cancer
adc
cell
pharmaceutical composition
antibody
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023515569A
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English (en)
Japanese (ja)
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JP2023545359A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/IB2021/058273 external-priority patent/WO2022054009A2/en
Publication of JP2023545359A publication Critical patent/JP2023545359A/ja
Publication of JP2023545359A5 publication Critical patent/JP2023545359A5/ja
Pending legal-status Critical Current

Links

JP2023515569A 2020-09-12 2021-09-11 抗her2抗体-薬物複合体治療のためのスコアリング方法 Pending JP2023545359A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063077604P 2020-09-12 2020-09-12
US63/077,604 2020-09-12
PCT/IB2021/058273 WO2022054009A2 (en) 2020-09-12 2021-09-11 A scoring method for an anti-her2 antibody-drug conjugate therapy

Publications (2)

Publication Number Publication Date
JP2023545359A JP2023545359A (ja) 2023-10-30
JP2023545359A5 true JP2023545359A5 (https=) 2024-09-11

Family

ID=77801755

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023515569A Pending JP2023545359A (ja) 2020-09-12 2021-09-11 抗her2抗体-薬物複合体治療のためのスコアリング方法

Country Status (10)

Country Link
US (1) US20240426826A1 (https=)
EP (1) EP4211598B1 (https=)
JP (1) JP2023545359A (https=)
KR (1) KR20230066094A (https=)
CN (1) CN116601713A (https=)
AU (2) AU2021340002B9 (https=)
CA (1) CA3195062A1 (https=)
ES (1) ES3064041T3 (https=)
IL (1) IL301265A (https=)
WO (1) WO2022054009A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240037740A1 (en) * 2022-07-28 2024-02-01 Applied Materials, Inc. Method and system for automatic ihc marker-her2 score
EP4623936A1 (en) * 2022-11-22 2025-10-01 Keymed Biosciences (Chengdu) Co., Ltd. Fused ring compound, conjugate thereof and use thereof
WO2025103192A1 (zh) * 2023-11-16 2025-05-22 上海齐鲁制药研究中心有限公司 一种氘代喜树碱化合物及其制备和应用
WO2025162211A1 (zh) * 2024-01-29 2025-08-07 正大天晴药业集团股份有限公司 抗her2抗体药物偶联物治疗胃癌的用途

Family Cites Families (15)

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Publication number Priority date Publication date Assignee Title
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
DK1071700T3 (da) 1998-04-20 2010-06-07 Glycart Biotechnology Ag Glykosylerings-modifikation af antistoffer til forbedring af antistofafhængig cellulær cytotoksicitet
CA2953239A1 (en) 2000-10-06 2002-04-18 Kyowa Hakko Kirin Co., Ltd. Antibody composition-producing cell
EP2854851A4 (en) * 2012-06-01 2016-03-30 Momenta Pharmaceuticals Inc Methods related to trastuzumab
IL310627B2 (en) * 2014-01-31 2026-04-01 Daiichi Sankyo Co Ltd Anti-HER2 antibody-drug conjugates, compositions containing them and uses thereof
GB201502590D0 (en) * 2015-02-16 2015-04-01 Lonza Ag Method and apparatus for designing proteins
MX2017015260A (es) * 2015-06-03 2018-02-19 Squibb Bristol Myers Co Anticuerpos anti receptor de factor de necrosis tumoral inducible por glucocorticoide (gitr) para diagnostico del cancer.
CN110651189B (zh) * 2017-03-03 2024-10-25 特雷斯生物有限公司 肽疫苗
EP3659110A1 (en) * 2017-07-24 2020-06-03 Ventana Medical Systems, Inc. Methods and systems for evaluation of immune cell infiltrate in tumor samples
EP3721373B1 (en) * 2017-12-07 2025-03-05 Ventana Medical Systems, Inc. Deep-learning systems and methods for joint cell and region classification in biological images
EP3797296B1 (en) * 2018-05-21 2024-09-04 Genentech, Inc. Her2 heterogeneity as a biomarker in cancer
US11030744B2 (en) * 2018-06-26 2021-06-08 Astrazeneca Computational Pathology Gmbh Deep learning method for tumor cell scoring on cancer biopsies
US12020493B2 (en) * 2018-07-27 2024-06-25 Ventana Medical Systems, Inc. Systems for automated in situ hybridization analysis
WO2022162164A1 (en) * 2021-01-29 2022-08-04 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods of assessing the risk of developing progressive multifocal leukoencephalopathy in patients treated with vla-4 antagonists

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