JP2023544721A5 - - Google Patents
Info
- Publication number
- JP2023544721A5 JP2023544721A5 JP2023519658A JP2023519658A JP2023544721A5 JP 2023544721 A5 JP2023544721 A5 JP 2023544721A5 JP 2023519658 A JP2023519658 A JP 2023519658A JP 2023519658 A JP2023519658 A JP 2023519658A JP 2023544721 A5 JP2023544721 A5 JP 2023544721A5
- Authority
- JP
- Japan
- Prior art keywords
- partial sample
- dna
- partial
- sample
- methylation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063086000P | 2020-09-30 | 2020-09-30 | |
| US63/086,000 | 2020-09-30 | ||
| US202063105183P | 2020-10-23 | 2020-10-23 | |
| US63/105,183 | 2020-10-23 | ||
| PCT/US2021/071649 WO2022073012A1 (en) | 2020-09-30 | 2021-09-29 | Compositions and methods for analyzing dna using partitioning and a methylation-dependent nuclease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023544721A JP2023544721A (ja) | 2023-10-25 |
| JP2023544721A5 true JP2023544721A5 (https=) | 2024-09-30 |
Family
ID=78333328
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023519658A Pending JP2023544721A (ja) | 2020-09-30 | 2021-09-29 | 分配およびメチル化依存性ヌクレアーゼを使用してｄｎａを解析するための組成物および方法 |
| JP2023519657A Pending JP2023544720A (ja) | 2020-09-30 | 2021-09-29 | Ｄｎａメチル化分配アッセイのシグナル対ノイズ比を改善するための方法およびシステム |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023519657A Pending JP2023544720A (ja) | 2020-09-30 | 2021-09-29 | Ｄｎａメチル化分配アッセイのシグナル対ノイズ比を改善するための方法およびシステム |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US20220154285A1 (https=) |
| EP (2) | EP4222278A1 (https=) |
| JP (2) | JP2023544721A (https=) |
| CA (2) | CA3193183A1 (https=) |
| WO (2) | WO2022073011A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023547620A (ja) | 2020-10-23 | 2023-11-13 | ガーダント ヘルス， インコーポレイテッド | 分配および塩基変換を使用してｄｎａを解析するための組成物および方法 |
| WO2022204730A1 (en) * | 2021-03-25 | 2022-09-29 | Guardant Health, Inc. | Methods and compositions for quantifying immune cell dna |
| IL293202A (en) * | 2022-05-22 | 2023-12-01 | Nucleix Ltd | Useful combinations of restriction enzymes |
| EP4536845A1 (en) * | 2022-06-13 | 2025-04-16 | Freenome Holdings, Inc. | Sequence process validation methods and compositions |
| JP2025522763A (ja) * | 2022-06-30 | 2025-07-17 | ガーダント ヘルス， インコーポレイテッド | 異常にメチル化されたｄｎａの富化 |
| NL2033070B1 (en) * | 2022-09-19 | 2024-03-25 | Univ Twente | Method for detecting CpG methylation in a DNA target sequence |
| EP4646493A1 (en) * | 2023-01-04 | 2025-11-12 | Natera, Inc. | Methods and compositions for amplifying methylated target dna molecules |
| EP4655070A1 (en) * | 2023-01-27 | 2025-12-03 | The Regents of the University of California | Methods of hyper- and hypo-methylation analysis for disease detection |
| WO2024211551A1 (en) | 2023-04-06 | 2024-10-10 | Glaxosmithkline Intellectual Property (No.4) Limited | Methods for treating and monitoring cancer |
| IL324647A (en) * | 2023-05-19 | 2026-01-01 | Nucleix Ltd | Detection of methylation changes in DNA samples using restriction enzymes and high-throughput sequencing |
| CN116926194A (zh) * | 2023-06-29 | 2023-10-24 | 纳昂达(南京)生物科技有限公司 | 一种检测dna样本甲基化状态的方法 |
| WO2025106807A1 (en) * | 2023-11-16 | 2025-05-22 | The Board Of Trustees Of The Leland Stanford Junior University | Classification of samples using methylation enrichment |
| WO2025165106A1 (ko) * | 2024-01-29 | 2025-08-07 | 주식회사 지씨지놈 | 핵산의 메틸화 마커 검출 방법 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6582908B2 (en) | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
| US20030017081A1 (en) | 1994-02-10 | 2003-01-23 | Affymetrix, Inc. | Method and apparatus for imaging a sample on a device |
| DE69528706T2 (de) | 1994-08-19 | 2003-06-12 | Pe Corp. (Ny), Foster City | Gekoppeltes ampflikation- und ligationverfahren |
| GB9620209D0 (en) | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
| GB9626815D0 (en) | 1996-12-23 | 1997-02-12 | Cemu Bioteknik Ab | Method of sequencing DNA |
| US6969488B2 (en) | 1998-05-22 | 2005-11-29 | Solexa, Inc. | System and apparatus for sequential processing of analytes |
| AR021833A1 (es) | 1998-09-30 | 2002-08-07 | Applied Research Systems | Metodos de amplificacion y secuenciacion de acido nucleico |
| US6818395B1 (en) | 1999-06-28 | 2004-11-16 | California Institute Of Technology | Methods and apparatus for analyzing polynucleotide sequences |
| US7501245B2 (en) | 1999-06-28 | 2009-03-10 | Helicos Biosciences Corp. | Methods and apparatuses for analyzing polynucleotide sequences |
| AU7537200A (en) | 1999-09-29 | 2001-04-30 | Solexa Ltd. | Polynucleotide sequencing |
| ATE377093T1 (de) | 2000-07-07 | 2007-11-15 | Visigen Biotechnologies Inc | Sequenzbestimmung in echtzeit |
| WO2003046146A2 (en) | 2001-11-28 | 2003-06-05 | Applera Corporation | Compositions and methods of selective nucleic acid isolation |
| ATE443765T1 (de) | 2003-03-21 | 2009-10-15 | Santaris Pharma As | Analoga kurzer interferierender rna (sirna) |
| WO2005040399A2 (en) * | 2003-10-21 | 2005-05-06 | Orion Genomics Llc | Methods for quantitative determination of methylation density in a dna locus |
| US7169560B2 (en) | 2003-11-12 | 2007-01-30 | Helicos Biosciences Corporation | Short cycle methods for sequencing polynucleotides |
| US7170050B2 (en) | 2004-09-17 | 2007-01-30 | Pacific Biosciences Of California, Inc. | Apparatus and methods for optical analysis of molecules |
| CA2579150C (en) | 2004-09-17 | 2014-11-25 | Pacific Biosciences Of California, Inc. | Apparatus and method for analysis of molecules |
| US7482120B2 (en) | 2005-01-28 | 2009-01-27 | Helicos Biosciences Corporation | Methods and compositions for improving fidelity in a nucleic acid synthesis reaction |
| US7282337B1 (en) | 2006-04-14 | 2007-10-16 | Helicos Biosciences Corporation | Methods for increasing accuracy of nucleic acid sequencing |
| US8486630B2 (en) | 2008-11-07 | 2013-07-16 | Industrial Technology Research Institute | Methods for accurate sequence data and modified base position determination |
| WO2010080617A2 (en) * | 2008-12-19 | 2010-07-15 | The Board Of Trustees Of The University Of Illinois | Detecting and sorting methylated dna using a synthetic nanopore |
| US20130157266A1 (en) | 2009-03-15 | 2013-06-20 | Ribomed Biotechnologies, Inc. | Abscription based molecular detection of dna methylation |
| US20110237444A1 (en) * | 2009-11-20 | 2011-09-29 | Life Technologies Corporation | Methods of mapping genomic methylation patterns |
| US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| CN104781421B (zh) | 2012-09-04 | 2020-06-05 | 夸登特健康公司 | 检测稀有突变和拷贝数变异的系统和方法 |
| US20160040229A1 (en) | 2013-08-16 | 2016-02-11 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| ES2660989T3 (es) | 2013-12-28 | 2018-03-27 | Guardant Health, Inc. | Métodos y sistemas para detectar variantes genéticas |
| EP4358097A1 (en) | 2014-07-25 | 2024-04-24 | University of Washington | Methods of determining tissues and/or cell types giving rise to cell-free dna, and methods of identifying a disease or disorder using same |
| US11384382B2 (en) * | 2016-04-14 | 2022-07-12 | Guardant Health, Inc. | Methods of attaching adapters to sample nucleic acids |
| KR102522067B1 (ko) * | 2016-05-03 | 2023-04-13 | 유니버시티 헬스 네트워크 | 무-세포 메틸화된 dna의 포획 방법 및 이의 이용 |
| WO2018009723A1 (en) | 2016-07-06 | 2018-01-11 | Guardant Health, Inc. | Methods for fragmentome profiling of cell-free nucleic acids |
| US9850523B1 (en) | 2016-09-30 | 2017-12-26 | Guardant Health, Inc. | Methods for multi-resolution analysis of cell-free nucleic acids |
| MX2019007444A (es) | 2016-12-22 | 2019-08-16 | Guardant Health Inc | Metodos y sistemas para analisis de moleculas de acido nucleico. |
| SG11202007686VA (en) * | 2018-02-12 | 2020-09-29 | 10X Genomics Inc | Methods characterizing multiple analytes from individual cells or cell populations |
| WO2020160414A1 (en) | 2019-01-31 | 2020-08-06 | Guardant Health, Inc. | Compositions and methods for isolating cell-free dna |
-
2021
- 2021-09-29 EP EP21798252.9A patent/EP4222278A1/en active Pending
- 2021-09-29 WO PCT/US2021/071648 patent/WO2022073011A1/en not_active Ceased
- 2021-09-29 JP JP2023519658A patent/JP2023544721A/ja active Pending
- 2021-09-29 CA CA3193183A patent/CA3193183A1/en active Pending
- 2021-09-29 EP EP21806592.8A patent/EP4222279A1/en active Pending
- 2021-09-29 CA CA3193090A patent/CA3193090A1/en active Pending
- 2021-09-29 US US17/489,687 patent/US20220154285A1/en active Pending
- 2021-09-29 JP JP2023519657A patent/JP2023544720A/ja active Pending
- 2021-09-29 WO PCT/US2021/071649 patent/WO2022073012A1/en not_active Ceased
- 2021-09-29 US US17/489,677 patent/US20220162670A1/en active Pending
-
2022
- 2022-12-22 US US18/087,724 patent/US11946106B2/en active Active
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