JP2024523401A5 - - Google Patents

Info

Publication number
JP2024523401A5
JP2024523401A5 JP2023577904A JP2023577904A JP2024523401A5 JP 2024523401 A5 JP2024523401 A5 JP 2024523401A5 JP 2023577904 A JP2023577904 A JP 2023577904A JP 2023577904 A JP2023577904 A JP 2023577904A JP 2024523401 A5 JP2024523401 A5 JP 2024523401A5
Authority
JP
Japan
Prior art keywords
cancer
type
dna
sample
specific
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023577904A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024523401A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/034382 external-priority patent/WO2022271730A1/en
Publication of JP2024523401A publication Critical patent/JP2024523401A/ja
Publication of JP2024523401A5 publication Critical patent/JP2024523401A5/ja
Pending legal-status Critical Current

Links

JP2023577904A 2021-06-21 2022-06-21 コピー数情報に基づく組織起源分析のための方法および組成物 Pending JP2024523401A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163213050P 2021-06-21 2021-06-21
US63/213,050 2021-06-21
PCT/US2022/034382 WO2022271730A1 (en) 2021-06-21 2022-06-21 Methods and compositions for copy-number informed tissue-of-origin analysis

Publications (2)

Publication Number Publication Date
JP2024523401A JP2024523401A (ja) 2024-06-28
JP2024523401A5 true JP2024523401A5 (https=) 2025-06-30

Family

ID=82655348

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023577904A Pending JP2024523401A (ja) 2021-06-21 2022-06-21 コピー数情報に基づく組織起源分析のための方法および組成物

Country Status (4)

Country Link
US (1) US20240263241A1 (https=)
EP (1) EP4359562A1 (https=)
JP (1) JP2024523401A (https=)
WO (1) WO2022271730A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202308392D0 (en) * 2023-06-06 2023-07-19 Fu Guoliang Methods, compositions, and kits for preparing library and targeted sequencing
US20250250638A1 (en) * 2023-10-06 2025-08-07 Guardant Health, Inc. Genomic and methylation biomarkers for prediction of copy number loss / gene deletion

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6582908B2 (en) 1990-12-06 2003-06-24 Affymetrix, Inc. Oligonucleotides
US20030017081A1 (en) 1994-02-10 2003-01-23 Affymetrix, Inc. Method and apparatus for imaging a sample on a device
WO2003046146A2 (en) 2001-11-28 2003-06-05 Applera Corporation Compositions and methods of selective nucleic acid isolation
ATE443765T1 (de) 2003-03-21 2009-10-15 Santaris Pharma As Analoga kurzer interferierender rna (sirna)
US8835358B2 (en) 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
US9892230B2 (en) 2012-03-08 2018-02-13 The Chinese University Of Hong Kong Size-based analysis of fetal or tumor DNA fraction in plasma
DK2850212T3 (da) * 2012-05-18 2020-03-23 Clinical Genomics Pty Ltd Fremgangsmåde til screening for colorektal cancer
GB2559073A (en) 2012-06-08 2018-07-25 Pacific Biosciences California Inc Modified base detection with nanopore sequencing
CN104781421B (zh) 2012-09-04 2020-06-05 夸登特健康公司 检测稀有突变和拷贝数变异的系统和方法
EP4358097A1 (en) 2014-07-25 2024-04-24 University of Washington Methods of determining tissues and/or cell types giving rise to cell-free dna, and methods of identifying a disease or disorder using same
IL305462A (en) 2015-07-23 2023-10-01 Univ Hong Kong Chinese DNA fragmentation pattern analysis suitable clean
CN114959918A (zh) * 2016-02-29 2022-08-30 基础医疗股份有限公司 用于评估肿瘤突变负荷的方法和系统
KR102522067B1 (ko) * 2016-05-03 2023-04-13 유니버시티 헬스 네트워크 무-세포 메틸화된 dna의 포획 방법 및 이의 이용
US9850523B1 (en) 2016-09-30 2017-12-26 Guardant Health, Inc. Methods for multi-resolution analysis of cell-free nucleic acids
MX2019007444A (es) 2016-12-22 2019-08-16 Guardant Health Inc Metodos y sistemas para analisis de moleculas de acido nucleico.
WO2019144057A1 (en) * 2018-01-19 2019-07-25 The University Of North Carolina At Chapel Hill Methylation markers for melanoma and uses thereof
WO2020020174A1 (en) 2018-07-23 2020-01-30 The Chinese University Of Hong Kong Cell-free dna damage analysis and its clinical applications
WO2020023420A2 (en) * 2018-07-23 2020-01-30 Guardant Health, Inc. Methods and systems for adjusting tumor mutational burden by tumor fraction and coverage
WO2020092807A1 (en) * 2018-10-31 2020-05-07 Guardant Health, Inc. Methods, compositions and systems for calibrating epigenetic partitioning assays
WO2020160414A1 (en) 2019-01-31 2020-08-06 Guardant Health, Inc. Compositions and methods for isolating cell-free dna
US11891653B2 (en) * 2019-09-30 2024-02-06 Guardant Health, Inc. Compositions and methods for analyzing cell-free DNA in methylation partitioning assays
JP2023541368A (ja) 2020-08-18 2023-10-02 デルフィ ダイアグノスティックス インコーポレイテッド がんを評価するための無細胞dna断片サイズ密度のための方法及びシステム

Similar Documents

Publication Publication Date Title
JP7434215B2 (ja) 無細胞メチル化dnaを捕捉する方法及びその使用
JP2023544721A5 (https=)
JP2023544721A (ja) 分配およびメチル化依存性ヌクレアーゼを使用してdnaを解析するための組成物および方法
EP4247973B1 (en) Detecting methylation changes in dna samples using restriction enzymes and high throughput sequencing
EP4628593A1 (en) Method for detecting methylation and mutation states of dna sample
JP2023551292A5 (https=)
JP2024523401A5 (https=)
JP2023547620A5 (https=)
CN119421958A (zh) 鉴别癌症的甲基化标志物及应用
Liu et al. Analysis of genome-wide in cell free DNA methylation: progress and prospect
JP2024540168A5 (https=)
Kumar et al. Techniques/tools to study epigenetic biomarkers in human cancer detection
US20250277270A1 (en) Heatrich-bs: heat enrichment of cpg-rich regions for bisulfite sequencing
KR20240046525A (ko) 세포-유리 dna에 대한 tet-보조 피리딘 보란 시퀀싱과 관련된 조성물 및 방법
TW201934568A (zh) 一種用於檢測食道癌的基因標誌物及其用途和檢測方法
JP2024511425A5 (https=)
CN116145267A (zh) 一种全基因组dna胞嘧啶羟甲基化修饰的单碱基精确度建库方法
CN117778568A (zh) 鉴别胃癌的标志物及应用
JP5116939B2 (ja) 哺乳動物由来の検体の癌化度を評価する方法
RU2586502C1 (ru) СПОСОБ КАРТИРОВАНИЯ ПОЛОЖЕНИЙ РЯДА МЕТИЛИРОВАННЫХ НУКЛЕОТИДНЫХ ПОСЛЕДОВАТЕЛЬНОСТЕЙ Pu(5mC)GPy В ПРОТЯЖЕННОЙ ДНК ДЛЯ ПОСТРОЕНИЯ ЭПИГЕНЕТИЧЕСКОГО ПРОФИЛЯ И ВЫЯВЛЕНИЯ АНОМАЛЬНО МЕТИЛИРОВАННЫХ УЧАСТКОВ ДНК
RU2804962C1 (ru) Способ обнаружения и анализа метилирования геномных участков ДНК в биологических образцах перифирической крови больных неходжкинской лимфомой
US20250308636A1 (en) Inferring cnvs from the distribution of molecules in hyper partition
US20250201344A1 (en) Methods and systems for identifying an origin of a variant
Huang Cell-free DNA Methylation Signatures in Cancer Detection and Classification
WO2023137294A1 (en) Method for detecting cancer using 5-hydroxymethylcytosine (5-hmc)