JP2023543261A5 - - Google Patents

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Publication number
JP2023543261A5
JP2023543261A5 JP2023519178A JP2023519178A JP2023543261A5 JP 2023543261 A5 JP2023543261 A5 JP 2023543261A5 JP 2023519178 A JP2023519178 A JP 2023519178A JP 2023519178 A JP2023519178 A JP 2023519178A JP 2023543261 A5 JP2023543261 A5 JP 2023543261A5
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JP
Japan
Prior art keywords
her2
mutation
administered
subject
her2 antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2023519178A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023543261A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/071606 external-priority patent/WO2022067347A1/en
Publication of JP2023543261A publication Critical patent/JP2023543261A/ja
Publication of JP2023543261A5 publication Critical patent/JP2023543261A5/ja
Withdrawn legal-status Critical Current

Links

JP2023519178A 2020-09-28 2021-09-27 ツカチニブを抗her2抗体と組み合わせて用いてher2変化により駆動される固形腫瘍を処置する方法 Withdrawn JP2023543261A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202063084481P 2020-09-28 2020-09-28
US63/084,481 2020-09-28
US202063113245P 2020-11-13 2020-11-13
US63/113,245 2020-11-13
US202163222335P 2021-07-15 2021-07-15
US63/222,335 2021-07-15
PCT/US2021/071606 WO2022067347A1 (en) 2020-09-28 2021-09-27 Methods of treating solid tumors driven by her2 alterations with tucatinib in combination with an anti-her2 antibody

Publications (2)

Publication Number Publication Date
JP2023543261A JP2023543261A (ja) 2023-10-13
JP2023543261A5 true JP2023543261A5 (https=) 2024-10-07

Family

ID=78464001

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023519178A Withdrawn JP2023543261A (ja) 2020-09-28 2021-09-27 ツカチニブを抗her2抗体と組み合わせて用いてher2変化により駆動される固形腫瘍を処置する方法

Country Status (10)

Country Link
US (1) US20230372342A1 (https=)
EP (1) EP4217400A1 (https=)
JP (1) JP2023543261A (https=)
KR (1) KR20230078705A (https=)
CN (1) CN116437924A (https=)
AU (1) AU2021349384A1 (https=)
CA (1) CA3197165A1 (https=)
IL (1) IL301405A (https=)
MX (1) MX2023003406A (https=)
WO (1) WO2022067347A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023230429A1 (en) * 2022-05-22 2023-11-30 Seagen Inc. Methods of treating colorectal cancer with tucatinib in combination with an anti-her2 antibody
EP4676543A1 (en) 2023-03-10 2026-01-14 Seagen Inc. Methods of treating cancer using anti-her2 antibody-drug conjugates and her2 kinase inhibitors
US20250228858A1 (en) 2023-12-20 2025-07-17 Boehringer Ingelheim International Gmbh Anti-cancer combination therapy

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US4683203A (en) 1984-04-14 1987-07-28 Redco N.V. Immobilized enzymes, processes for preparing same, and use thereof
US4957735A (en) 1984-06-12 1990-09-18 The University Of Tennessee Research Corporation Target-sensitive immunoliposomes- preparation and characterization
US5019369A (en) 1984-10-22 1991-05-28 Vestar, Inc. Method of targeting tumors in humans
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4902505A (en) 1986-07-30 1990-02-20 Alkermes Chimeric peptides for neuropeptide delivery through the blood-brain barrier
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5004697A (en) 1987-08-17 1991-04-02 Univ. Of Ca Cationized antibodies for delivery through the blood-brain barrier
IE61148B1 (en) 1988-03-10 1994-10-05 Ici Plc Method of detecting nucleotide sequences
US5055303A (en) 1989-01-31 1991-10-08 Kv Pharmaceutical Company Solid controlled release bioadherent emulsions
US5271961A (en) 1989-11-06 1993-12-21 Alkermes Controlled Therapeutics, Inc. Method for producing protein microspheres
US5188837A (en) 1989-11-13 1993-02-23 Nova Pharmaceutical Corporation Lipsopheres for controlled delivery of substances
US5268164A (en) 1990-04-23 1993-12-07 Alkermes, Inc. Increasing blood-brain barrier permeability with permeabilizer peptides
US5254342A (en) 1991-09-30 1993-10-19 University Of Southern California Compositions and methods for enhanced transepithelial and transendothelial transport or active agents
US5534496A (en) 1992-07-07 1996-07-09 University Of Southern California Methods and compositions to enhance epithelial drug transport
US5514670A (en) 1993-08-13 1996-05-07 Pharmos Corporation Submicron emulsions for delivery of peptides
US5498531A (en) 1993-09-10 1996-03-12 President And Fellows Of Harvard College Intron-mediated recombinant techniques and reagents
US5413197A (en) 1994-03-14 1995-05-09 Baer; Larry G. Parking brake valve
WO2018200505A1 (en) 2017-04-24 2018-11-01 Genentech, Inc. Erbb2/her2 mutations in the transmbrane or juxtamembrane domain
BR112019022280A2 (pt) * 2017-04-28 2020-05-19 Seattle Genetics Inc tratamento de cânceres de her2 positivo
TW202042820A (zh) * 2019-01-28 2020-12-01 美商西雅圖遺傳學股份有限公司 以妥卡替尼(Tucatinib)治療乳癌之方法

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