JP2023540796A5 - - Google Patents

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Publication number
JP2023540796A5
JP2023540796A5 JP2023516053A JP2023516053A JP2023540796A5 JP 2023540796 A5 JP2023540796 A5 JP 2023540796A5 JP 2023516053 A JP2023516053 A JP 2023516053A JP 2023516053 A JP2023516053 A JP 2023516053A JP 2023540796 A5 JP2023540796 A5 JP 2023540796A5
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JP
Japan
Prior art keywords
antibody
cdr1
cdr2
cdr3
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2023516053A
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English (en)
Japanese (ja)
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JP2023540796A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/049761 external-priority patent/WO2022056192A1/en
Publication of JP2023540796A publication Critical patent/JP2023540796A/ja
Priority to JP2024155472A priority Critical patent/JP2025003970A/ja
Publication of JP2023540796A5 publication Critical patent/JP2023540796A5/ja
Withdrawn legal-status Critical Current

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JP2023516053A 2020-09-11 2021-09-10 ベータ鎖媒介性免疫を調節するための方法及び組成物 Withdrawn JP2023540796A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024155472A JP2025003970A (ja) 2020-09-11 2024-09-10 ベータ鎖媒介性免疫を調節するための方法及び組成物

Applications Claiming Priority (25)

Application Number Priority Date Filing Date Title
US202063077387P 2020-09-11 2020-09-11
US202063077314P 2020-09-11 2020-09-11
US202063077397P 2020-09-11 2020-09-11
US63/077,387 2020-09-11
US63/077,397 2020-09-11
US63/077,314 2020-09-11
US202063104265P 2020-10-22 2020-10-22
US202063104247P 2020-10-22 2020-10-22
US202063104220P 2020-10-22 2020-10-22
US63/104,265 2020-10-22
US63/104,220 2020-10-22
US63/104,247 2020-10-22
US202163142930P 2021-01-28 2021-01-28
US202163142940P 2021-01-28 2021-01-28
US202163142944P 2021-01-28 2021-01-28
US63/142,930 2021-01-28
US63/142,944 2021-01-28
US63/142,940 2021-01-28
US202163165053P 2021-03-23 2021-03-23
US63/165,053 2021-03-23
US202163176112P 2021-04-16 2021-04-16
US63/176,112 2021-04-16
US202163237972P 2021-08-27 2021-08-27
US63/237,972 2021-08-27
PCT/US2021/049761 WO2022056192A1 (en) 2020-09-11 2021-09-10 Methods and compositions for modulating beta chain mediated immunity

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024155472A Division JP2025003970A (ja) 2020-09-11 2024-09-10 ベータ鎖媒介性免疫を調節するための方法及び組成物

Publications (2)

Publication Number Publication Date
JP2023540796A JP2023540796A (ja) 2023-09-26
JP2023540796A5 true JP2023540796A5 (https=) 2024-09-19

Family

ID=80629876

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2023516053A Withdrawn JP2023540796A (ja) 2020-09-11 2021-09-10 ベータ鎖媒介性免疫を調節するための方法及び組成物
JP2024155472A Pending JP2025003970A (ja) 2020-09-11 2024-09-10 ベータ鎖媒介性免疫を調節するための方法及び組成物

Family Applications After (1)

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JP2024155472A Pending JP2025003970A (ja) 2020-09-11 2024-09-10 ベータ鎖媒介性免疫を調節するための方法及び組成物

Country Status (11)

Country Link
US (3) US11965024B2 (https=)
EP (1) EP4211170A4 (https=)
JP (2) JP2023540796A (https=)
KR (2) KR20240142592A (https=)
AU (1) AU2021339754A1 (https=)
CA (1) CA3194968A1 (https=)
IL (1) IL301254A (https=)
MX (1) MX2023002948A (https=)
TW (1) TW202227495A (https=)
UY (1) UY39415A (https=)
WO (1) WO2022056192A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2021010857A (es) 2019-03-11 2021-12-15 Janssen Biotech Inc Anticuerpos biespecificos anti-v(beta17)/anti-cd123.
WO2022056197A1 (en) 2020-09-11 2022-03-17 Janssen Biotech, Inc. Immune targeting molecules and uses thereof
TW202227495A (zh) 2020-09-11 2022-07-16 美商健生生物科技公司 用於調節β鏈介導之免疫的方法及組成物
JP2024507180A (ja) * 2021-02-16 2024-02-16 ヤンセン ファーマシューティカ エヌ.ベー. Bcma、gprc5d、及びcd3を標的とする三重特異的抗体
CN114940710B (zh) * 2022-06-07 2023-09-26 恺佧生物科技(上海)有限公司 一种提高重组人psma蛋白表达的方法
WO2026035888A1 (en) * 2024-08-06 2026-02-12 Janssen Biotech, Inc. Methods and compositions for modulating beta chain mediated immunity

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6221352B1 (en) * 1989-03-21 2001-04-24 The Immune Response Corporation Method of preventing the proliferation of Vβ14 or Vβ17-Expressing T cells
US6413516B1 (en) * 1989-03-21 2002-07-02 The Immune Response Corporation Peptides and methods against psoriasis
FR2681875A1 (fr) * 1991-09-26 1993-04-02 Immunotech Sa Nouvelles molecules de adn recombinants contenant la partie codante d'une chaine vb17 du recepteur pour l'antigene des cellules t, procede de preparation, anticorps et medicaments les renfermant.
US6084087A (en) 1991-09-27 2000-07-04 New York Society For The Ruptured And Crippled Maintaing The Hospital For Special Surgery DNA encoding conserved T-cell receptor sequences
US6670127B2 (en) 1997-09-16 2003-12-30 Egea Biosciences, Inc. Method for assembly of a polynucleotide encoding a target polypeptide
PT1015576E (pt) 1997-09-16 2005-09-30 Egea Biosciences Llc Metodo para a sintese quimica completa e montagem de genes e de genomas
US6737056B1 (en) 1999-01-15 2004-05-18 Genentech, Inc. Polypeptide variants with altered effector function
JP5356648B2 (ja) 2003-02-20 2013-12-04 シアトル ジェネティックス, インコーポレイテッド 抗cd70抗体−医薬結合体、ならびに癌および免疫障害の処置のためのそれらの使用
WO2006028936A2 (en) 2004-09-02 2006-03-16 Genentech, Inc. Heteromultimeric molecules
AU2006232287B2 (en) 2005-03-31 2011-10-06 Chugai Seiyaku Kabushiki Kaisha Methods for producing polypeptides by regulating polypeptide association
EP1877075A4 (en) 2005-04-25 2008-07-30 Pfizer ANTIBODY TO MYOSTATIN
US7585960B2 (en) 2005-05-11 2009-09-08 Theramab Gmbh Nucleic acids encoding superagonistic anti-CD28 antibodies
DE102005028778A1 (de) 2005-06-22 2006-12-28 SUNJÜT Deutschland GmbH Mehrlagige Folie mit einer Barriere- und einer antistatischen Lage
US7612181B2 (en) 2005-08-19 2009-11-03 Abbott Laboratories Dual variable domain immunoglobulin and uses thereof
JP2009541275A (ja) 2006-06-22 2009-11-26 ノボ・ノルデイスク・エー/エス 二重特異性抗体の生産
US9315577B2 (en) 2008-05-01 2016-04-19 Amgen Inc. Anti-hepcidin antibodies and methods of use
US20110097339A1 (en) 2008-07-18 2011-04-28 Domantis Limited Compositions monovalent for CD28 binding and methods of use
UA109633C2 (uk) 2008-12-09 2015-09-25 Антитіло людини проти тканинного фактора
WO2010129304A2 (en) 2009-04-27 2010-11-11 Oncomed Pharmaceuticals, Inc. Method for making heteromultimeric molecules
JO3182B1 (ar) 2009-07-29 2018-03-08 Regeneron Pharma مضادات حيوية بشرية عالية الالفة مع تولد الاوعية البشرية - 2
HRP20241208T1 (hr) 2010-04-20 2024-11-22 Genmab A/S Heterodimerni proteini koji sadrže fc fragment protutijela i postupci za njihovu proizvodnju
BR112012031727B1 (pt) 2010-06-15 2022-03-29 Genmab A/S Conjugado de droga-anticorpo, composição farmacêutica, e, uso do conjugado de droga- anticorpo
NZ604510A (en) 2010-08-17 2013-10-25 Csl Ltd Dilutable biocidal compositions and methods of use
ES2758994T3 (es) 2010-11-05 2020-05-07 Zymeworks Inc Diseño anticuerpo heterodimérico estable con mutaciones en el dominio Fc
BR112014010580B1 (pt) 2011-11-04 2021-01-12 Zymeworks, Inc. constructo de fc heteromultimérico isolado, composição, uso de um constructo de fc heteromultimérico isolado, composição de ácido nucléico e método para expressar o constructo de fc heteromultimérico isolado
JOP20200236A1 (ar) 2012-09-21 2017-06-16 Regeneron Pharma الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها
US9790274B2 (en) 2013-03-14 2017-10-17 The Board Of Regents Of The University Of Texas System Monoclonal antibodies targeting EpCAM for detection of prostate cancer lymph node metastases
NZ759969A (en) 2013-12-20 2022-12-23 Fred Hutchinson Cancer Center Tagged chimeric effector molecules and receptors thereof
SG10201913782UA (en) 2014-07-21 2020-03-30 Novartis Ag Treatment of cancer using a cll-1 chimeric antigen receptor
MA40609B1 (fr) 2014-09-05 2020-05-29 Janssen Pharmaceutica Nv Agents de liaison cd123 et leurs utilisations
EP3215538A4 (en) * 2014-11-07 2018-07-04 Igenica Biotherapeutics, Inc. Anti-cd39 antibodies and uses thereof
CA2979759C (en) 2015-04-16 2023-08-08 Eisai R&D Management Co., Ltd. Anti-human notch4 antibody
JO3711B1 (ar) 2015-07-13 2021-01-31 H Lundbeck As أجسام مضادة محددة لبروتين تاو وطرق استعمالها
US10800843B2 (en) 2015-07-29 2020-10-13 Ngm Biopharmaceuticals, Inc. Beta klotho-binding proteins
GB201516272D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR Libraries
EP3356415B1 (en) 2015-09-29 2024-05-01 Amgen Inc. Asgr inhibitors for reduzing cholesterol levels
TWI790206B (zh) 2016-07-18 2023-01-21 法商賽諾菲公司 特異性結合至cd3和cd123的雙特異性抗體樣結合蛋白
WO2018112407A1 (en) 2016-12-15 2018-06-21 Duke University Antibodies and methods for depleting regulatory b10 cells and use in combination with immune checkpoint inhibitors
US11370830B2 (en) 2017-04-07 2022-06-28 The Rockefeller University Neutralizing antibodies that bind to the zika virus domain III envelope region
KR20200041834A (ko) 2017-06-01 2020-04-22 젠코어 인코포레이티드 Cd123 및 cd3에 결합하는 이중특이성 항체
JP7404252B2 (ja) 2017-11-08 2023-12-25 ヤフェイ シャンハイ バイオロジー メディスン サイエンス アンド テクノロジー カンパニー リミテッド 生体分子のコンジュゲートおよびその使用
MX2020014243A (es) 2018-06-19 2021-05-12 Biontech Us Inc Neoantigenos y usos de los mismos.
CA3105448A1 (en) 2018-07-03 2020-01-09 Elstar Therapeutics, Inc. Anti-tcr antibody molecules and uses thereof
GB2595980B (en) 2019-01-04 2023-06-14 Marengo Therapeutics Inc Anti-TCR antibody molecules and uses thereof
MX2021010857A (es) 2019-03-11 2021-12-15 Janssen Biotech Inc Anticuerpos biespecificos anti-v(beta17)/anti-cd123.
EP3986936A4 (en) 2019-06-21 2023-03-15 Single Cell Technology, Inc. ANTI-TIGIT ANTIBODIES
AU2020359070A1 (en) 2019-10-03 2022-04-21 Janssen Biotech, Inc. Methods for producing biotherapeutics with increased stability by sequence optimization
AU2021225870A1 (en) 2020-02-27 2022-10-20 Janssen Biotech, Inc. Materials and methods for modulating an immune response
WO2022056197A1 (en) * 2020-09-11 2022-03-17 Janssen Biotech, Inc. Immune targeting molecules and uses thereof
TW202227495A (zh) 2020-09-11 2022-07-16 美商健生生物科技公司 用於調節β鏈介導之免疫的方法及組成物
US20220089737A1 (en) 2020-09-11 2022-03-24 Janssen Biotech, Inc. Multi-specific immune targeting molecules and uses thereof

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