JP2023539493A5 - - Google Patents

Info

Publication number
JP2023539493A5
JP2023539493A5 JP2023513582A JP2023513582A JP2023539493A5 JP 2023539493 A5 JP2023539493 A5 JP 2023539493A5 JP 2023513582 A JP2023513582 A JP 2023513582A JP 2023513582 A JP2023513582 A JP 2023513582A JP 2023539493 A5 JP2023539493 A5 JP 2023539493A5
Authority
JP
Japan
Prior art keywords
antibody
amino acid
acid sequence
binding fragment
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023513582A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023539493A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/073816 external-priority patent/WO2022043538A1/en
Publication of JP2023539493A publication Critical patent/JP2023539493A/ja
Publication of JP2023539493A5 publication Critical patent/JP2023539493A5/ja
Pending legal-status Critical Current

Links

JP2023513582A 2020-08-29 2021-08-27 Bcl-2阻害剤への低下した感度を有する患者の治療方法 Pending JP2023539493A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063072113P 2020-08-29 2020-08-29
US63/072,113 2020-08-29
PCT/EP2021/073816 WO2022043538A1 (en) 2020-08-29 2021-08-27 Method of treatment of patients having reduced sensitivity to a bcl-2 inhibitor

Publications (2)

Publication Number Publication Date
JP2023539493A JP2023539493A (ja) 2023-09-14
JP2023539493A5 true JP2023539493A5 (enExample) 2024-09-03

Family

ID=77821706

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023513582A Pending JP2023539493A (ja) 2020-08-29 2021-08-27 Bcl-2阻害剤への低下した感度を有する患者の治療方法

Country Status (10)

Country Link
US (1) US20240182590A1 (enExample)
EP (1) EP4204098A1 (enExample)
JP (1) JP2023539493A (enExample)
KR (1) KR20230061421A (enExample)
CN (1) CN116249519A (enExample)
AU (1) AU2021334165A1 (enExample)
CA (1) CA3188634A1 (enExample)
IL (1) IL300996A (enExample)
MX (1) MX2023002318A (enExample)
WO (1) WO2022043538A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201800649D0 (en) 2018-01-16 2018-02-28 Argenx Bvba CD70 Combination Therapy
AU2019265019B2 (en) 2018-05-11 2025-11-06 Beam Therapeutics Inc. Methods of substituting pathogenic amino acids using programmable base editor systems
AU2023390486A1 (en) * 2022-12-08 2025-07-03 The Regents Of The University Of Colorado, A Body Corporate Methods for identifying resistance or response to venetoclax/hypomethylating agent/anti-cd70 agent treatment for acute myeloid leukemia

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1594542T3 (da) 2003-02-20 2010-10-11 Seattle Genetics Inc Anti-CD70 antistof-lægemiddelkonjugater og deres anvendelse ved behandling af cancer
US20080025989A1 (en) * 2003-02-20 2008-01-31 Seattle Genetics, Inc. Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders
AU2007333098A1 (en) 2006-12-14 2008-06-19 Medarex, Inc. Human antibodies that bind CD70 and uses thereof
US8546399B2 (en) 2009-05-26 2013-10-01 Abbvie Inc. Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
KR101923364B1 (ko) 2010-11-23 2018-11-30 애브비 인코포레이티드 아폽토시스­유도제의 염 및 결정형
US10391168B1 (en) * 2014-08-22 2019-08-27 University Of Bern Anti-CD70 combination therapy
US11001582B2 (en) 2016-03-10 2021-05-11 Assia Chemical Industries Ltd. Solid state forms of Venetoclax and processes for preparation of Venetoclax
WO2017212431A1 (en) 2016-06-09 2017-12-14 Dr. Reddy’S Laboratories Limited Solid forms of venetoclax and processes for the preparation of venetoclax
EP3481397A1 (en) 2016-07-06 2019-05-15 Concert Pharmaceuticals Inc. Deuterated venetoclax
CN107648185A (zh) 2016-07-25 2018-02-02 常州爱诺新睿医药技术有限公司 一种无定型Venetoclax与药用辅料的固体分散体及其制备方法
WO2018029711A2 (en) 2016-08-12 2018-02-15 Mylan Laboratories Limited Process for the preparation of venetoclax
US10800777B2 (en) 2016-10-14 2020-10-13 Mylan Laboratories Limited Polymorphic forms of VENCLEXTA
EP3333167A1 (en) 2016-12-09 2018-06-13 LEK Pharmaceuticals d.d. Solid forms of venetoclax
WO2018157803A1 (zh) 2017-02-28 2018-09-07 苏州科睿思制药有限公司 维奈妥拉的晶型及其制备方法
WO2018167652A1 (en) 2017-03-13 2018-09-20 Laurus Labs Limited Process for preparation of amorphous form of venetoclax
CN107089981A (zh) 2017-04-24 2017-08-25 杭州科耀医药科技有限公司 一种BCL‑2抑制剂Venetoclax的合成方法
GB2567613A (en) 2017-06-16 2019-04-24 Argenx Bvba Treatment for acute myeloid leukaemia
TWI848030B (zh) * 2018-12-18 2024-07-11 比利時商阿根思公司 Cd70組合治療

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