JP2023539128A5 - - Google Patents

Info

Publication number
JP2023539128A5
JP2023539128A5 JP2023512144A JP2023512144A JP2023539128A5 JP 2023539128 A5 JP2023539128 A5 JP 2023539128A5 JP 2023512144 A JP2023512144 A JP 2023512144A JP 2023512144 A JP2023512144 A JP 2023512144A JP 2023539128 A5 JP2023539128 A5 JP 2023539128A5
Authority
JP
Japan
Prior art keywords
max
genes
methylation level
sample
methylation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023512144A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023539128A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/046494 external-priority patent/WO2022040306A1/en
Publication of JP2023539128A publication Critical patent/JP2023539128A/ja
Publication of JP2023539128A5 publication Critical patent/JP2023539128A5/ja
Pending legal-status Critical Current

Links

JP2023512144A 2020-08-19 2021-08-18 非ホジキンリンパ腫の検出 Pending JP2023539128A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063067592P 2020-08-19 2020-08-19
US63/067,592 2020-08-19
PCT/US2021/046494 WO2022040306A1 (en) 2020-08-19 2021-08-18 Detecting non-hodgkin lymphoma

Publications (2)

Publication Number Publication Date
JP2023539128A JP2023539128A (ja) 2023-09-13
JP2023539128A5 true JP2023539128A5 (enExample) 2024-08-09

Family

ID=80323685

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023512144A Pending JP2023539128A (ja) 2020-08-19 2021-08-18 非ホジキンリンパ腫の検出

Country Status (8)

Country Link
US (1) US20230357852A1 (enExample)
EP (1) EP4200445A4 (enExample)
JP (1) JP2023539128A (enExample)
KR (1) KR20230049122A (enExample)
CN (1) CN116670299A (enExample)
AU (1) AU2021329899A1 (enExample)
CA (1) CA3188230A1 (enExample)
WO (1) WO2022040306A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2816122A1 (en) 2008-02-15 2014-12-24 Mayo Foundation For Medical Education And Research Detecting neoplasm from a stool sample
US8361720B2 (en) 2010-11-15 2013-01-29 Exact Sciences Corporation Real time cleavage assay
CA2902916C (en) 2013-03-14 2018-08-28 Mayo Foundation For Medical Education And Research Detecting neoplasm
CN120700143A (zh) 2014-03-31 2025-09-26 梅奥医学教育和研究基金会 检测结直肠赘生物
US10184154B2 (en) 2014-09-26 2019-01-22 Mayo Foundation For Medical Education And Research Detecting cholangiocarcinoma
US10435755B2 (en) 2015-03-27 2019-10-08 Exact Sciences Development Company, Llc Detecting esophageal disorders
CN114574585A (zh) 2015-08-31 2022-06-03 梅约医药教育及研究基金会 检测胃肿瘤
CN108350485A (zh) 2015-10-30 2018-07-31 精密科学发展有限责任公司 血浆dna的多重扩增检测测定以及分离和检测
CN109563546B (zh) 2016-05-05 2022-09-09 精密科学发展有限责任公司 通过分析甲基化dna来检测肺肿瘤
KR102892245B1 (ko) 2017-01-27 2025-11-27 이그젝트 싸이언스 디블롭먼트 컴패니, 엘엘씨 메틸화된 dna 분석에 의한 결장 신조직형성의 검출
JP7277460B2 (ja) 2017-11-30 2023-05-19 マヨ ファウンデーション フォア メディカル エデュケーション アンド リサーチ 乳癌の検出
US10648025B2 (en) 2017-12-13 2020-05-12 Exact Sciences Development Company, Llc Multiplex amplification detection assay II
CA3127329A1 (en) 2019-01-24 2020-07-30 Mayo Foundation For Medical Education And Research Detecting endometrial cancer
US11702704B2 (en) 2019-10-31 2023-07-18 Mayo Foundation For Medical Education And Research Detecting ovarian cancer
CN121605200A (zh) * 2024-06-24 2026-03-03 京东方科技集团股份有限公司 组合物及用于富集经转换的cfDNA片段的方法
WO2026000128A1 (zh) * 2024-06-24 2026-01-02 京东方科技集团股份有限公司 组合物及用于弥漫大b细胞淋巴瘤化疗疗效预测的方法
CN119040461B (zh) * 2024-09-20 2025-04-25 广州优润康医疗科技有限公司 一种检测肾癌的引物探针组合、试剂盒及应用

Family Cites Families (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288609A (en) 1984-04-27 1994-02-22 Enzo Diagnostics, Inc. Capture sandwich hybridization method and composition
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5011769A (en) 1985-12-05 1991-04-30 Meiogenics U.S. Limited Partnership Methods for detecting nucleic acid sequences
US5359100A (en) 1987-10-15 1994-10-25 Chiron Corporation Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers
US5124246A (en) 1987-10-15 1992-06-23 Chiron Corporation Nucleic acid multimers and amplified nucleic acid hybridization assays using same
US5403711A (en) 1987-11-30 1995-04-04 University Of Iowa Research Foundation Nucleic acid hybridization and amplification method for detection of specific sequences in which a complementary labeled nucleic acid probe is cleaved
CA1340807C (en) 1988-02-24 1999-11-02 Lawrence T. Malek Nucleic acid amplification process
US5639611A (en) 1988-12-12 1997-06-17 City Of Hope Allele specific polymerase chain reaction
CA2036946C (en) 1990-04-06 2001-10-16 Kenneth V. Deugau Indexing linkers
US5849481A (en) 1990-07-27 1998-12-15 Chiron Corporation Nucleic acid hybridization assays employing large comb-type branched polynucleotides
US6872816B1 (en) 1996-01-24 2005-03-29 Third Wave Technologies, Inc. Nucleic acid detection kits
US5994069A (en) 1996-01-24 1999-11-30 Third Wave Technologies, Inc. Detection of nucleic acids by multiple sequential invasive cleavages
US5846717A (en) 1996-01-24 1998-12-08 Third Wave Technologies, Inc. Detection of nucleic acid sequences by invader-directed cleavage
US5338671A (en) 1992-10-07 1994-08-16 Eastman Kodak Company DNA amplification with thermostable DNA polymerase and polymerase inhibiting antibody
SE501439C2 (sv) 1993-06-22 1995-02-13 Pharmacia Lkb Biotech Sätt och anordning för analys av polynukleotidsekvenser
WO1995014106A2 (en) 1993-11-17 1995-05-26 Id Biomedical Corporation Cycling probe cleavage detection of nucleic acid sequences
EP0734436B1 (en) 1993-11-30 1999-04-14 McGILL UNIVERSITY Inhibition of dna methyltransferase
US5851770A (en) 1994-04-25 1998-12-22 Variagenics, Inc. Detection of mismatches by resolvase cleavage using a magnetic bead support
AU693198B2 (en) 1994-04-25 1998-06-25 Avitech Diagnostics, Inc. Detection of mutation by resolvase cleavage
ES2185719T3 (es) 1994-12-23 2003-05-01 Dade Behring Inc Deteccion de acidos nucleicos por formacion de un producto catalizada por diana.
US5882867A (en) 1995-06-07 1999-03-16 Dade Behring Marburg Gmbh Detection of nucleic acids by formation of template-dependent product
US5773258A (en) 1995-08-25 1998-06-30 Roche Molecular Systems, Inc. Nucleic acid amplification using a reversibly inactivated thermostable enzyme
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
US5965408A (en) 1996-07-09 1999-10-12 Diversa Corporation Method of DNA reassembly by interrupting synthesis
CA2239683A1 (en) 1995-12-22 1997-07-03 Dade Behring Marburg Gmbh Homogeneous amplification and detection of nucleic acids
US5985557A (en) 1996-01-24 1999-11-16 Third Wave Technologies, Inc. Invasive cleavage of nucleic acids
AU713667B2 (en) 1996-04-12 1999-12-09 Phri Properties, Inc. Detection probes, kits and assays
US6017704A (en) 1996-06-03 2000-01-25 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US5786146A (en) 1996-06-03 1998-07-28 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US6096273A (en) 1996-11-05 2000-08-01 Clinical Micro Sensors Electrodes linked via conductive oligomers to nucleic acids
US6251594B1 (en) 1997-06-09 2001-06-26 Usc/Norris Comprehensive Cancer Ctr. Cancer diagnostic method based upon DNA methylation differences
US6013459A (en) 1997-06-12 2000-01-11 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
DE19754482A1 (de) 1997-11-27 1999-07-01 Epigenomics Gmbh Verfahren zur Herstellung komplexer DNA-Methylierungs-Fingerabdrücke
US6063573A (en) 1998-01-27 2000-05-16 Clinical Micro Sensors, Inc. Cycling probe technology using electron transfer detection
EP1053352B1 (en) 1998-02-04 2002-09-18 Variagenics, Inc. Mismatch detection techniques
US6235502B1 (en) 1998-09-18 2001-05-22 Molecular Staging Inc. Methods for selectively isolating DNA using rolling circle amplification
US7700324B1 (en) 1998-11-03 2010-04-20 The Johns Hopkins University School Of Medicine Methylated CpG island amplification (MCA)
US7662594B2 (en) 2002-09-20 2010-02-16 New England Biolabs, Inc. Helicase-dependent amplification of RNA
WO2005023091A2 (en) 2003-09-05 2005-03-17 The Trustees Of Boston University Method for non-invasive prenatal diagnosis
US8088976B2 (en) * 2005-02-24 2012-01-03 Monsanto Technology Llc Methods for genetic control of plant pest infestation and compositions thereof
EP3591068A1 (en) 2006-02-02 2020-01-08 The Board of Trustees of the Leland Stanford Junior University Non-invasive fetal genetic screening by digital analysis
WO2009117327A2 (en) 2008-03-15 2009-09-24 Hologic, Inc. Compositions and methods for analysis of nucleic acid molecules during amplification reactions
US9115386B2 (en) 2008-09-26 2015-08-25 Children's Medical Center Corporation Selective oxidation of 5-methylcytosine by TET-family proteins
WO2011127136A1 (en) 2010-04-06 2011-10-13 University Of Chicago Composition and methods related to modification of 5-hydroxymethylcytosine (5-hmc)
WO2012031329A1 (en) * 2010-09-10 2012-03-15 Murdoch Childrens Research Institute Assay for detection and monitoring of cancer
US8916344B2 (en) 2010-11-15 2014-12-23 Exact Sciences Corporation Methylation assay
US8361720B2 (en) 2010-11-15 2013-01-29 Exact Sciences Corporation Real time cleavage assay
US8715937B2 (en) 2010-11-15 2014-05-06 Exact Sciences Corporation Mutation detection assay
US8808990B2 (en) 2011-05-12 2014-08-19 Exact Sciences Corporation Serial isolation of multiple DNA targets from stool
CN104450680A (zh) 2011-05-12 2015-03-25 精密科学公司 核酸的分离
US9315853B2 (en) 2012-01-30 2016-04-19 Exact Sciences Corporation Modification of DNA on magnetic beads
JP2015526096A (ja) * 2012-08-31 2015-09-10 国防医学院National Defense Medical Center 癌のスクリーニング方法
US9212392B2 (en) 2012-09-25 2015-12-15 Exact Sciences Corporation Normalization of polymerase activity
US10253358B2 (en) 2013-11-04 2019-04-09 Exact Sciences Development Company, Llc Multiple-control calibrators for DNA quantitation
US9984201B2 (en) * 2015-01-18 2018-05-29 Youhealth Biotech, Limited Method and system for determining cancer status
US11162139B2 (en) 2016-03-02 2021-11-02 Shanghai Epican Genetech Co. Ltd. Method for genomic profiling of DNA 5-methylcytosine and 5-hydroxymethylcytosine
WO2017176630A1 (en) 2016-04-07 2017-10-12 The Board Of Trustees Of The Leland Stanford Junior University Noninvasive diagnostics by sequencing 5-hydroxymethylated cell-free dna
US12258632B2 (en) * 2016-07-06 2025-03-25 Case Western Reserve University Methods and compositions for detecting esophageal neoplasias and/or metaplasias in the esophagus
NZ765943A (en) 2018-01-08 2022-10-28 Ludwig Inst For Cancer Res Ltd Bisulfite-free, base-resolution identification of cytosine modifications

Similar Documents

Publication Publication Date Title
JP2023539128A5 (enExample)
JP2024512627A5 (enExample)
JP2022553575A5 (enExample)
JP2022526415A5 (enExample)
JP2025063204A5 (enExample)
US10100351B2 (en) High-throughput sequencing detection method for methylated CpG islands
CN105695572B (zh) 一种基于Indel和SSR位点技术大批量且高效开发分子标记的方法
JP2021503943A5 (enExample)
CN107488725A (zh) 适用于单细胞基因组甲基化测序的文库建立方法及其应用
US10648032B2 (en) High-throughput sequencing method for methylated CpG island in trace DNA
Davidović et al. Methylation-specific PCR: four steps in primer design
CN111893216A (zh) 核酸质谱检测dna/rna的产品及检测方法
US20200232014A1 (en) Systems and methods for isolating nucleic acids
CN113025701A (zh) 非酒精性脂肪性肝病易感基因的早筛方法及试剂盒
CN112553325A (zh) 舒芬太尼个体化用药基因的指导方法及试剂盒
CN111172260A (zh) 检测人尿液或血液样本中的线粒体基因组的方法及试剂盒
CN113025702B (zh) 强直性脊柱炎易感基因的早筛方法及试剂盒
Novroski Emerging technologies for DNA analysis of challenged samples
WO2013040060A2 (en) Nucleic acids for multiplex detection of hepatitis c virus
CN114703261A (zh) 一种多重pcr特异性基因检测引物组、试剂盒、方法和应用
Al-Turkmani et al. Molecular assessment of human diseases in the clinical laboratory
RU2404256C1 (ru) Способ подвидовой дифференциации штаммов возбудителя чумы методом секвенирования
CN112501283A (zh) 卡马西平个体化用药基因的指导方法及试剂盒
CN112592972A (zh) 弥漫性毒性甲状腺肿易感基因的早筛方法及试剂盒
Pipaliya Chapter-2 Advancements in Genetic Profiling and Engineering using Microarray Technology