JP2023538159A5 - - Google Patents
Info
- Publication number
- JP2023538159A5 JP2023538159A5 JP2022530800A JP2022530800A JP2023538159A5 JP 2023538159 A5 JP2023538159 A5 JP 2023538159A5 JP 2022530800 A JP2022530800 A JP 2022530800A JP 2022530800 A JP2022530800 A JP 2022530800A JP 2023538159 A5 JP2023538159 A5 JP 2023538159A5
- Authority
- JP
- Japan
- Prior art keywords
- amino
- methyl
- methylquinoline
- cyclohexyl
- chloro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2020/108213 | 2020-08-10 | ||
| CN2020108213 | 2020-08-10 | ||
| PCT/CN2021/111910 WO2022033492A1 (en) | 2020-08-10 | 2021-08-10 | Quinoline compounds and compositions for inhibiting ezh2 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023538159A JP2023538159A (ja) | 2023-09-07 |
| JP2023538159A5 true JP2023538159A5 (cg-RX-API-DMAC10.html) | 2024-08-16 |
| JP7768880B2 JP7768880B2 (ja) | 2025-11-12 |
Family
ID=77520462
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022530800A Active JP7768880B2 (ja) | 2020-08-10 | 2021-08-10 | Ｅｚｈ２を阻害するためのキノリン化合物および組成物 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US12473273B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP4041725B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP7768880B2 (cg-RX-API-DMAC10.html) |
| KR (1) | KR20230051116A (cg-RX-API-DMAC10.html) |
| CN (2) | CN114555589B (cg-RX-API-DMAC10.html) |
| AR (1) | AR123185A1 (cg-RX-API-DMAC10.html) |
| AU (1) | AU2021323828B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA3180139A1 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2985111T3 (cg-RX-API-DMAC10.html) |
| IL (1) | IL297332B2 (cg-RX-API-DMAC10.html) |
| TW (1) | TWI910207B (cg-RX-API-DMAC10.html) |
| WO (1) | WO2022033492A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR123185A1 (es) | 2020-08-10 | 2022-11-09 | Novartis Ag | Compuestos y composiciones para inhibir ezh2 |
| PE20241731A1 (es) * | 2022-02-01 | 2024-08-19 | Lilly Co Eli | Procesos para la preparacion de degradadores selectivos del receptor de estrogeno |
| CN117384153A (zh) * | 2022-07-12 | 2024-01-12 | 上海赛岚生物科技有限公司 | 一类甲基转移酶抑制剂及其用途 |
| CN118515653B (zh) * | 2024-07-23 | 2024-12-10 | 西湖制药(杭州)有限公司 | 一种ezh2特异性抑制剂及其制备方法和用途 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2779780A (en) | 1955-03-01 | 1957-01-29 | Du Pont | 1, 4-diamino-2, 3-dicyano-1, 4-bis (substituted mercapto) butadienes and their preparation |
| EP0647450A1 (en) | 1993-09-09 | 1995-04-12 | BEHRINGWERKE Aktiengesellschaft | Improved prodrugs for enzyme mediated activation |
| JP2002532415A (ja) | 1998-12-16 | 2002-10-02 | ワーナー−ランバート・カンパニー | Ｍｅｋ阻害剤による関節炎の治療 |
| AU7349801A (en) | 2000-07-19 | 2002-01-30 | Warner Lambert Co | Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids |
| CA2478065C (en) | 2002-03-08 | 2013-01-08 | Eisai Co. Ltd. | Macrocyclic compounds useful as pharmaceuticals |
| SG2013013339A (en) | 2002-03-13 | 2014-12-30 | Array Biopharma Inc | N3 alkylated benzimidazole derivatives as mek inhibitors |
| SE0202134D0 (sv) * | 2002-07-08 | 2002-07-08 | Astrazeneca Ab | Therapeutic agents |
| JP2006124387A (ja) | 2004-09-30 | 2006-05-18 | Taisho Pharmaceut Co Ltd | 新規なキノリン、テトラヒドロキナゾリン、及びピリミジン誘導体と、これらを使用することに関連した治療方法 |
| GB0510390D0 (en) | 2005-05-20 | 2005-06-29 | Novartis Ag | Organic compounds |
| MX2008002114A (es) | 2005-07-21 | 2008-04-17 | Ardea Biosciences Inc | Inhibidores de n-(arilamino)-sulfonamida de mek. |
| JO2660B1 (en) | 2006-01-20 | 2012-06-17 | نوفارتيس ايه جي | Pi-3 inhibitors and methods of use |
| BRPI0816769A2 (pt) | 2007-09-12 | 2016-11-29 | Hoffmann La Roche | combinações de compostos inibidores de fosfoinositida 3-cinase e agentes quimioterapêuticos, e métodos de uso |
| WO2009055730A1 (en) | 2007-10-25 | 2009-04-30 | Genentech, Inc. | Process for making thienopyrimidine compounds |
| US8168784B2 (en) | 2008-06-20 | 2012-05-01 | Abbott Laboratories | Processes to make apoptosis promoters |
| WO2012068589A2 (en) * | 2010-11-19 | 2012-05-24 | Constellation Pharmaceuticals | Modulators of methyl modifying enzymes, compositions and uses thereof |
| AP2016009605A0 (en) * | 2014-06-17 | 2016-12-31 | Pfizer | Substituted dihydroisoquinolinone compounds |
| JP2019524872A (ja) * | 2016-06-20 | 2019-09-05 | ノバルティス アーゲー | 癌の治療に有用なイミダゾピリミジン化合物 |
| WO2018195450A1 (en) | 2017-04-21 | 2018-10-25 | Epizyme, Inc. | Combination therapies with ehmt2 inhibitors |
| CN109912576B (zh) * | 2019-03-20 | 2021-11-19 | 华东理工大学 | 环状或螺环二胺类嘧啶-异羟肟酸及其用途 |
| DK4034535T3 (da) * | 2019-09-26 | 2026-04-07 | Novartis Ag | Aza-quinolinforbindelser og anvendelser deraf |
| AR123185A1 (es) | 2020-08-10 | 2022-11-09 | Novartis Ag | Compuestos y composiciones para inhibir ezh2 |
-
2021
- 2021-08-09 AR ARP210102216A patent/AR123185A1/es unknown
- 2021-08-10 IL IL297332A patent/IL297332B2/en unknown
- 2021-08-10 KR KR1020227019646A patent/KR20230051116A/ko active Pending
- 2021-08-10 US US17/919,490 patent/US12473273B2/en active Active
- 2021-08-10 TW TW110129535A patent/TWI910207B/zh active
- 2021-08-10 CA CA3180139A patent/CA3180139A1/en active Pending
- 2021-08-10 WO PCT/CN2021/111910 patent/WO2022033492A1/en not_active Ceased
- 2021-08-10 JP JP2022530800A patent/JP7768880B2/ja active Active
- 2021-08-10 EP EP21762334.7A patent/EP4041725B1/en active Active
- 2021-08-10 CN CN202180005903.7A patent/CN114555589B/zh active Active
- 2021-08-10 ES ES21762334T patent/ES2985111T3/es active Active
- 2021-08-10 AU AU2021323828A patent/AU2021323828B2/en active Active
- 2021-08-10 CN CN202411371645.6A patent/CN119431341A/zh active Pending
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