JP2023537943A - ＭＡＲＣ１発現を阻害するためのＲＮＡｉコンストラクト及び方法 - Google Patents

ＭＡＲＣ１発現を阻害するためのＲＮＡｉコンストラクト及び方法 Download PDF

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JP2023537943A
JP2023537943A JP2023509499A JP2023509499A JP2023537943A JP 2023537943 A JP2023537943 A JP 2023537943A JP 2023509499 A JP2023509499 A JP 2023509499A JP 2023509499 A JP2023509499 A JP 2023509499A JP 2023537943 A JP2023537943 A JP 2023537943A
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seq
sequence
rnai construct
strand comprises
nucleotides
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JP2023537943A5 (https=
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ジャスティン ケー． マリー，
ジュン ジャン，
オリバー ホーマン，
ジェイソン シー． ロング，
ブライアン ミード，
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Amgen Inc
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Amgen Inc
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JP2023509499A 2020-08-13 2021-08-12 ＭＡＲＣ１発現を阻害するためのＲＮＡｉコンストラクト及び方法 Pending JP2023537943A (ja)

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JP2025282055A JP2026049002A (ja) 2020-08-13 2025-12-25 ＭＡＲＣ１発現を阻害するためのＲＮＡｉコンストラクト及び方法

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US202063065190P 2020-08-13 2020-08-13
US63/065,190 2020-08-13
US202163214016P 2021-06-23 2021-06-23
US63/214,016 2021-06-23
PCT/US2021/045784 WO2022036126A2 (en) 2020-08-13 2021-08-12 RNAi CONSTRUCTS AND METHODS FOR INHIBITING MARC1 EXPRESSION

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EP (1) EP4196584A2 (https=)
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CA (1) CA3190868A1 (https=)
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JP2024525078A (ja) * 2021-07-08 2024-07-09 オリックス ファーマシューティカルズ，インコーポレーテッド ＭＡＲＣ１遺伝子を標的にするＲＮＡｉ製剤及びその用途

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EP4347820A1 (en) * 2021-05-28 2024-04-10 Novo Nordisk A/S Compositions and methods for inhibiting mitochondria amidoxime reducing component 1 (marc1) expression
US20230240232A1 (en) * 2022-01-28 2023-08-03 Pioneer Hi-Bred International, Inc. Soybean variety 5psym14
US20230240241A1 (en) * 2022-01-28 2023-08-03 Pioneer Hi-Bred International, Inc. Soybean variety 5pryl83
US20230255169A1 (en) * 2022-02-16 2023-08-17 Syngenta Crop Protection Ag Soybean variety
CN120322552A (zh) * 2022-07-27 2025-07-15 e-生物有限公司 核酸化合物
US20240268301A1 (en) * 2023-02-10 2024-08-15 Pioneer Hi-Bred International, Inc. Soybean variety 5ptcn76
KR20250137186A (ko) * 2023-03-08 2025-09-17 올릭스 주식회사 비만의 예방 또는 치료용 RNAi 제제 및 이를 이용한 병용 요법
EP4680249A1 (en) * 2023-03-16 2026-01-21 Arrowhead Pharmaceuticals, Inc. Rnai agents for inhibiting expression of mitochondrial amidoxime reducing component 1 (marc1), pharmaceutical compositions thereof, and methods of use
WO2024222898A1 (zh) * 2023-04-28 2024-10-31 北京福元医药股份有限公司 用于抑制marc1基因表达的双链核糖核酸及其修饰物、缀合物和用途
US20250268171A1 (en) * 2024-02-28 2025-08-28 Pioneer Hi-Bred International, Inc. Soybean variety 5ppzm06
US20250268198A1 (en) * 2024-02-28 2025-08-28 Pioneer Hi-Bred International, Inc. Soybean variety 5pgbu05
US20250268178A1 (en) * 2024-02-28 2025-08-28 Pioneer Hi-Bred International, Inc. Soybean variety 5peve11
US20250268175A1 (en) * 2024-02-28 2025-08-28 Pioneer Hi-Bred International, Inc. Soybean variety 5paks02
US20250268190A1 (en) * 2024-02-28 2025-08-28 Pioneer Hi-Bred International, Inc. Soybean variety 5phsb14
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