JP2023537630A5 - - Google Patents

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Publication number
JP2023537630A5
JP2023537630A5 JP2023511590A JP2023511590A JP2023537630A5 JP 2023537630 A5 JP2023537630 A5 JP 2023537630A5 JP 2023511590 A JP2023511590 A JP 2023511590A JP 2023511590 A JP2023511590 A JP 2023511590A JP 2023537630 A5 JP2023537630 A5 JP 2023537630A5
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JP
Japan
Prior art keywords
dimethyl
tetrahydro
benzo
azepine
alkyl
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JP2023511590A
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English (en)
Japanese (ja)
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JP2023537630A (ja
JP7696997B2 (ja
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Priority claimed from PCT/US2021/045720 external-priority patent/WO2022036080A1/en
Publication of JP2023537630A publication Critical patent/JP2023537630A/ja
Publication of JP2023537630A5 publication Critical patent/JP2023537630A5/ja
Application granted granted Critical
Publication of JP7696997B2 publication Critical patent/JP7696997B2/ja
Active legal-status Critical Current
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JP2023511590A 2020-08-14 2021-08-12 シグマリガンド化合物としての縮合アザ環およびその使用 Active JP7696997B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063066064P 2020-08-14 2020-08-14
US63/066,064 2020-08-14
PCT/US2021/045720 WO2022036080A1 (en) 2020-08-14 2021-08-12 Condensed azacycles as sigma ligand compounds and uses thereof

Publications (3)

Publication Number Publication Date
JP2023537630A JP2023537630A (ja) 2023-09-04
JP2023537630A5 true JP2023537630A5 (enExample) 2024-08-21
JP7696997B2 JP7696997B2 (ja) 2025-06-23

Family

ID=77640761

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023511590A Active JP7696997B2 (ja) 2020-08-14 2021-08-12 シグマリガンド化合物としての縮合アザ環およびその使用

Country Status (7)

Country Link
US (2) US12006300B2 (enExample)
EP (1) EP4196222A1 (enExample)
JP (1) JP7696997B2 (enExample)
CN (1) CN116829540A (enExample)
AU (1) AU2021325927A1 (enExample)
CA (1) CA3186083A1 (enExample)
WO (1) WO2022036080A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3208490A1 (en) 2021-02-24 2022-09-01 Aleksandrs Zavoronkovs Analogs for the treatment of disease
WO2024105225A1 (en) 2022-11-18 2024-05-23 Universitat De Barcelona Synergistic combinations of a sigma receptor 1 (s1r) antagonist and a soluble epoxide hydrolase inhibitor (sehi) and their use in the treatment of pain
WO2024114782A1 (en) * 2022-12-01 2024-06-06 National Institute Of Biological Sciences, Beijing Small-molecule modulators of spike protein
WO2024173727A2 (en) * 2023-02-16 2024-08-22 Minerva Neurosciences, Inc. Use of condensed azacycle compounds for the treatment of lysosomal storage disorders
CN121398820A (zh) 2023-05-26 2026-01-23 英特拉生物科学股份公司 用于治疗癌症的氧代哌嗪衍生物
WO2025090588A1 (en) * 2023-10-24 2025-05-01 Minerva Neurosciences, Inc. Roluperidone for the treatment of lysosomal storage disorders and their symptoms

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5763263A (en) 1995-11-27 1998-06-09 Dehlinger; Peter J. Method and apparatus for producing position addressable combinatorial libraries
US7166617B2 (en) 2000-02-29 2007-01-23 Mitsubishi Pharma Corporation Cyclic amide derivatives
DE10222034A1 (de) * 2002-05-17 2003-11-27 Bayer Ag Tetrahydroisochinolin-Derivate
GB0224557D0 (en) 2002-10-22 2002-11-27 Glaxo Group Ltd Novel compounds
PL2671869T3 (pl) * 2011-02-02 2016-09-30 Pochodna tetrahydroizochinoliny
CA2834548C (en) 2011-04-28 2021-06-01 The Broad Institute, Inc. Inhibitors of histone deacetylase
WO2014053568A1 (en) 2012-10-02 2014-04-10 Sanofi Indolyldihydroimidazopyrimidinone derivatives, preparation thereof and therapeutic use thereof
JP2019501143A (ja) * 2015-12-04 2019-01-17 ヴィーブ ヘルスケア ユーケー リミテッド テトラヒドロイソキノリン誘導体
WO2017190109A1 (en) 2016-04-29 2017-11-02 Board Of Regents, The University Of Texas System Sigma receptor binders
WO2018218051A1 (en) 2017-05-25 2018-11-29 Enanta Pharmaceuticals, Inc. Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof
TWI815887B (zh) * 2018-05-15 2023-09-21 美商愛彼特生物製藥股份有限公司 經取代的2,2'-雙嘧啶基化合物、其類似物及其使用方法
WO2022013136A1 (en) * 2020-07-14 2022-01-20 F. Hoffmann-La Roche Ag Hydroisoquinoline or hydronaphthyridine compounds for the treatment of autoimmune disease
WO2022169961A1 (en) 2021-02-04 2022-08-11 University Of Florida Research Foundation, Incorporated Sigma receptor ligands for treating sars-cov-2 infection

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