JP2023537403A5 - - Google Patents

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Publication number
JP2023537403A5
JP2023537403A5 JP2023509723A JP2023509723A JP2023537403A5 JP 2023537403 A5 JP2023537403 A5 JP 2023537403A5 JP 2023509723 A JP2023509723 A JP 2023509723A JP 2023509723 A JP2023509723 A JP 2023509723A JP 2023537403 A5 JP2023537403 A5 JP 2023537403A5
Authority
JP
Japan
Prior art keywords
approximately
mtx
pegylated uricase
uricase
pharmaceutical product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023509723A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023537403A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/045350 external-priority patent/WO2022035828A1/en
Publication of JP2023537403A publication Critical patent/JP2023537403A/ja
Publication of JP2023537403A5 publication Critical patent/JP2023537403A5/ja
Pending legal-status Critical Current

Links

JP2023509723A 2020-08-10 2021-08-10 痛風を治療する方法 Pending JP2023537403A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063063826P 2020-08-10 2020-08-10
US63/063,826 2020-08-10
US202163148982P 2021-02-12 2021-02-12
US63/148,982 2021-02-12
PCT/US2021/045350 WO2022035828A1 (en) 2020-08-10 2021-08-10 Methods of treating gout

Publications (2)

Publication Number Publication Date
JP2023537403A JP2023537403A (ja) 2023-08-31
JP2023537403A5 true JP2023537403A5 (https=) 2024-08-20

Family

ID=80247297

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023509723A Pending JP2023537403A (ja) 2020-08-10 2021-08-10 痛風を治療する方法

Country Status (11)

Country Link
US (2) US20230301999A1 (https=)
EP (2) EP4588513A3 (https=)
JP (1) JP2023537403A (https=)
KR (1) KR20230086660A (https=)
CN (1) CN116261463A (https=)
AU (1) AU2021324665A1 (https=)
BR (1) BR112023002458A2 (https=)
CA (1) CA3189100A1 (https=)
IL (1) IL300536A (https=)
MX (1) MX2023001740A (https=)
WO (1) WO2022035828A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG161247A1 (en) 2005-04-11 2010-05-27 Savient Pharmaceuticals Inc Variant forms of urate oxidase and use thereof
US9377454B2 (en) 2009-06-25 2016-06-28 Crealta Pharmaceuticals Llc Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy
CN116637177A (zh) 2016-11-11 2023-08-25 好利恩治疗美国公司 泼尼松和尿酸酶分子的组合疗法及其用途
WO2020160322A1 (en) 2019-01-30 2020-08-06 Horizon Pharma Rheumatology Llc Tolerization reduces intolerance to pegloticase and prolongs the urate lowering effect (triple)
WO2020160325A1 (en) 2019-01-30 2020-08-06 Horizon Pharma Rheumatology Llc Reducing immunogenicity to pegloticase
EP4588513A3 (en) * 2020-08-10 2025-10-22 Horizon Therapeutics USA, Inc. Methods of treating gout
WO2024088213A1 (en) * 2022-10-24 2024-05-02 Westlake Therapeutics (Shanghai) Co., Limited Combination to induce specific immune tolerance
US12201413B2 (en) 2023-03-01 2025-01-21 Washington University Free breathing dynamic contrast enhanced (DCE) liver MR imaging
US12269875B2 (en) 2023-08-03 2025-04-08 Jeff R. Peterson Gout flare prevention methods using IL-1BETA blockers

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE498409T1 (de) 1998-08-06 2011-03-15 Mountain View Pharmaceuticals Peg-uricase konjugate und verwendung davon
US6783965B1 (en) 2000-02-10 2004-08-31 Mountain View Pharmaceuticals, Inc. Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates
WO2000008196A2 (en) * 1998-08-06 2000-02-17 Duke University Urate oxidase
MX2007012548A (es) 2005-04-11 2008-03-11 Savient Pharmaceuticals Inc Formas variantes de urato oxidasa y uso de las mismas.
SG161247A1 (en) 2005-04-11 2010-05-27 Savient Pharmaceuticals Inc Variant forms of urate oxidase and use thereof
JP5033177B2 (ja) 2006-04-12 2012-09-26 サビエント ファーマセウティカルズ インク. 陽イオン界面活性剤によるタンパク質の精製
US9377454B2 (en) 2009-06-25 2016-06-28 Crealta Pharmaceuticals Llc Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy
KR20180120753A (ko) * 2016-03-11 2018-11-06 셀렉타 바이오사이언시즈, 인크. Peg화 우리카제의 제제 및 용량
CN116637177A (zh) 2016-11-11 2023-08-25 好利恩治疗美国公司 泼尼松和尿酸酶分子的组合疗法及其用途
ES3036482T3 (en) * 2017-03-11 2025-09-19 Cartesian Therapeutics Inc Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant
WO2020160325A1 (en) * 2019-01-30 2020-08-06 Horizon Pharma Rheumatology Llc Reducing immunogenicity to pegloticase
WO2020160324A1 (en) * 2019-01-30 2020-08-06 Horizon Pharma Rheumatology Llc Reducing immunogenicity to pegloticase
EP4588513A3 (en) * 2020-08-10 2025-10-22 Horizon Therapeutics USA, Inc. Methods of treating gout

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