JP2023537341A - 複数のポリペプチドをアッセイするためのシステム及び方法 - Google Patents
複数のポリペプチドをアッセイするためのシステム及び方法 Download PDFInfo
- Publication number
- JP2023537341A JP2023537341A JP2023507234A JP2023507234A JP2023537341A JP 2023537341 A JP2023537341 A JP 2023537341A JP 2023507234 A JP2023507234 A JP 2023507234A JP 2023507234 A JP2023507234 A JP 2023507234A JP 2023537341 A JP2023537341 A JP 2023537341A
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- nucleic acid
- binding
- beads
- capture moiety
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1062—Isolating an individual clone by screening libraries mRNA-Display, e.g. polypeptide and encoding template are connected covalently
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6818—Sequencing of polypeptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063057754P | 2020-07-28 | 2020-07-28 | |
| US63/057,754 | 2020-07-28 | ||
| PCT/US2021/043297 WO2022026458A1 (en) | 2020-07-28 | 2021-07-27 | Systems and methods for assaying a plurality of polypeptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023537341A true JP2023537341A (ja) | 2023-08-31 |
| JP2023537341A5 JP2023537341A5 (https=) | 2024-08-01 |
Family
ID=80036155
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023507234A Pending JP2023537341A (ja) | 2020-07-28 | 2021-07-27 | 複数のポリペプチドをアッセイするためのシステム及び方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230287490A1 (https=) |
| EP (1) | EP4189085A4 (https=) |
| JP (1) | JP2023537341A (https=) |
| CN (1) | CN116234927A (https=) |
| AU (1) | AU2021318522A1 (https=) |
| CA (1) | CA3187408A1 (https=) |
| WO (1) | WO2022026458A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025123212A1 (zh) * | 2023-12-12 | 2025-06-19 | 深圳华大生命科学研究院 | 一种基于目标检测模型的多肽信号提取方法 |
| WO2025165797A1 (en) * | 2024-01-30 | 2025-08-07 | Gene Company (Pty) Ltd. | Hepatocyte nuclear factor four alpha antisense rna 1 targeting polynucleotide and method of use and treatment thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010046680A1 (en) * | 1999-10-01 | 2001-11-29 | Zhongping Yu | Identification of polypeptides and nucleic acid molecules using linkage between DNA and polypeptide |
| JP2009542211A (ja) * | 2006-06-30 | 2009-12-03 | アムビト ビオスシエンセス コルポラチオン | 検出可能な核酸タグ |
| JP2013512691A (ja) * | 2009-12-07 | 2013-04-18 | プログノシス バイオサイエンシズ インコーポレイテッド | ペプチド提示アレイ |
| JP2015506699A (ja) * | 2012-02-02 | 2015-03-05 | インベンラ, インコーポレイテッド | 生物学的に活性なポリペプチドのハイスループットスクリーニング |
| JP2016523978A (ja) * | 2013-07-10 | 2016-08-12 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 核酸−タンパク質複合体に関する組成物及び方法 |
| WO2020095985A1 (ja) * | 2018-11-07 | 2020-05-14 | 公益財団法人川崎市産業振興財団 | ペプチド-核酸複合体 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8962238B2 (en) * | 2007-04-05 | 2015-02-24 | SpeedDx Pty Ltd | Nucleic acid enzymes and complexes and methods for their use |
-
2021
- 2021-07-27 AU AU2021318522A patent/AU2021318522A1/en active Pending
- 2021-07-27 EP EP21850216.9A patent/EP4189085A4/en active Pending
- 2021-07-27 JP JP2023507234A patent/JP2023537341A/ja active Pending
- 2021-07-27 CA CA3187408A patent/CA3187408A1/en active Pending
- 2021-07-27 CN CN202180066419.5A patent/CN116234927A/zh active Pending
- 2021-07-27 WO PCT/US2021/043297 patent/WO2022026458A1/en not_active Ceased
- 2021-07-27 US US18/007,032 patent/US20230287490A1/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010046680A1 (en) * | 1999-10-01 | 2001-11-29 | Zhongping Yu | Identification of polypeptides and nucleic acid molecules using linkage between DNA and polypeptide |
| JP2009542211A (ja) * | 2006-06-30 | 2009-12-03 | アムビト ビオスシエンセス コルポラチオン | 検出可能な核酸タグ |
| JP2013512691A (ja) * | 2009-12-07 | 2013-04-18 | プログノシス バイオサイエンシズ インコーポレイテッド | ペプチド提示アレイ |
| JP2015506699A (ja) * | 2012-02-02 | 2015-03-05 | インベンラ, インコーポレイテッド | 生物学的に活性なポリペプチドのハイスループットスクリーニング |
| JP2016523978A (ja) * | 2013-07-10 | 2016-08-12 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 核酸−タンパク質複合体に関する組成物及び方法 |
| WO2020095985A1 (ja) * | 2018-11-07 | 2020-05-14 | 公益財団法人川崎市産業振興財団 | ペプチド-核酸複合体 |
Non-Patent Citations (1)
| Title |
|---|
| GAN ET AL.: "Microbeads display of proteins using emulsion PCR and cell-free protein synthesis", BIOTECHNOL. PROG., vol. Vol. 24, Issue 5, JPN6025032279, 29 September 2008 (2008-09-29), pages 1107 - 1114, ISSN: 0005657168 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN116234927A (zh) | 2023-06-06 |
| US20230287490A1 (en) | 2023-09-14 |
| AU2021318522A1 (en) | 2023-03-23 |
| EP4189085A1 (en) | 2023-06-07 |
| CA3187408A1 (en) | 2022-02-03 |
| WO2022026458A1 (en) | 2022-02-03 |
| EP4189085A4 (en) | 2024-08-28 |
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