JP2023535808A5 - - Google Patents
Info
- Publication number
- JP2023535808A5 JP2023535808A5 JP2023506111A JP2023506111A JP2023535808A5 JP 2023535808 A5 JP2023535808 A5 JP 2023535808A5 JP 2023506111 A JP2023506111 A JP 2023506111A JP 2023506111 A JP2023506111 A JP 2023506111A JP 2023535808 A5 JP2023535808 A5 JP 2023535808A5
- Authority
- JP
- Japan
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2011813.9A GB202011813D0 (en) | 2020-07-29 | 2020-07-29 | Polypeptide |
| GB2011813.9 | 2020-07-29 | ||
| GBGB2100648.1A GB202100648D0 (en) | 2021-01-18 | 2021-01-18 | Polypeptide |
| GB2100648.1 | 2021-01-18 | ||
| GB2105924.1 | 2021-04-26 | ||
| GBGB2105924.1A GB202105924D0 (en) | 2021-04-26 | 2021-04-26 | Polypeptide |
| PCT/GB2021/051969 WO2022023761A2 (en) | 2020-07-29 | 2021-07-29 | Polypeptide |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023535808A JP2023535808A (ja) | 2023-08-21 |
| JP2023535808A5 true JP2023535808A5 (https=) | 2024-08-07 |
| JPWO2022023761A5 JPWO2022023761A5 (https=) | 2024-08-07 |
Family
ID=77265101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023506111A Pending JP2023535808A (ja) | 2020-07-29 | 2021-07-29 | 安定性の改善された変異型ベータ－グルコセレブロシダーゼ |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20240261433A1 (https=) |
| EP (2) | EP4118200B1 (https=) |
| JP (1) | JP2023535808A (https=) |
| KR (1) | KR20230042513A (https=) |
| CN (1) | CN116322744A (https=) |
| AU (1) | AU2021316875B2 (https=) |
| BR (1) | BR112023001583A2 (https=) |
| CA (1) | CA3189801A1 (https=) |
| DK (1) | DK4118200T3 (https=) |
| ES (1) | ES3057448T3 (https=) |
| FI (1) | FI4118200T3 (https=) |
| HR (1) | HRP20251591T1 (https=) |
| IL (1) | IL299811A (https=) |
| MX (1) | MX2023001137A (https=) |
| PT (1) | PT4118200T (https=) |
| WO (1) | WO2022023761A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025122912A1 (en) | 2023-12-08 | 2025-06-12 | Denali Therapeutics Inc. | Modified glucocerebrosidase polypeptides and methods of use thereof |
| WO2025166045A1 (en) | 2024-01-31 | 2025-08-07 | Alector Llc | β-GLUCOCEREBROSIDASE ENZYMES, FUSION PROTEINS AND COMPLEXES COMPRISING THE SAME, AND METHODS OF USE THEREOF |
| CN118086341B (zh) * | 2024-04-25 | 2024-08-02 | 上海凌医生物科技有限公司 | 在肝脏中高表达人源葡萄糖脑苷脂酶基因的表达框 |
| WO2026006173A1 (en) | 2024-06-24 | 2026-01-02 | Denali Therapeutics Inc. | Fusion proteins comprising modified glucocerebrosidase polypeptides and methods thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1775901A (en) * | 1999-11-17 | 2001-05-30 | Avigen, Inc. | Recombinant adeno-associated virus virions for the treatment of lysosomal disorders |
| AU2352201A (en) * | 1999-12-30 | 2001-07-16 | Maxygen Aps | Improved lysosomal enzymes and lysosomal enzyme activators |
| EP2154969B1 (en) | 2007-05-16 | 2015-11-18 | The Brigham and Women's Hospital, Inc. | Treatment of synucleinopathies |
| WO2011122950A1 (en) | 2010-04-01 | 2011-10-06 | Amsterdam Molecular Therapeutics (Amt) Ip B.V. | Monomeric duplex aav vectors |
| SI2638152T1 (sl) * | 2010-11-08 | 2016-12-30 | Amicus Therapeutics, Inc. | Variantni in rekombinantni proteini beta-glukocerebrozidaze s povišano stabilnostjo in povišano ohranjeno katalitično aktivnostjo |
| AU2013243948A1 (en) * | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins associated with human disease |
| US9574184B2 (en) * | 2013-09-25 | 2017-02-21 | Children's Hospital Medical Center | Lysosomal protein targeting sequence and therapeutic applications of same |
| KR102450833B1 (ko) * | 2016-04-15 | 2022-10-05 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | 혈우병 a 치료용 유전자 요법 |
| EP3692075A4 (en) | 2017-10-03 | 2022-02-09 | Prevail Therapeutics, Inc. | GENE THERAPIES FOR LYSOSOMAL DISEASES |
| KR102709597B1 (ko) | 2017-10-03 | 2024-09-26 | 프리베일 테라퓨틱스, 인크. | 리소좀 장애를 위한 유전자 요법 |
| WO2020012149A1 (en) | 2018-07-13 | 2020-01-16 | Ucl Business Ltd | Glucocerebrosidase gene therapy |
| WO2020012164A1 (en) | 2018-07-13 | 2020-01-16 | Ucl Business Ltd | Glucocerebrosidase gene therapy |
| US20220125892A1 (en) * | 2019-02-01 | 2022-04-28 | OXYRANE UK Ltd. | Glucocerebrosidase polypeptides |
-
2021
- 2021-07-29 EP EP21752123.6A patent/EP4118200B1/en active Active
- 2021-07-29 KR KR1020237007296A patent/KR20230042513A/ko active Pending
- 2021-07-29 CA CA3189801A patent/CA3189801A1/en active Pending
- 2021-07-29 ES ES21752123T patent/ES3057448T3/es active Active
- 2021-07-29 MX MX2023001137A patent/MX2023001137A/es unknown
- 2021-07-29 DK DK21752123.6T patent/DK4118200T3/da active
- 2021-07-29 US US18/017,158 patent/US20240261433A1/en active Pending
- 2021-07-29 PT PT217521236T patent/PT4118200T/pt unknown
- 2021-07-29 HR HRP20251591TT patent/HRP20251591T1/hr unknown
- 2021-07-29 JP JP2023506111A patent/JP2023535808A/ja active Pending
- 2021-07-29 WO PCT/GB2021/051969 patent/WO2022023761A2/en not_active Ceased
- 2021-07-29 CN CN202180066422.7A patent/CN116322744A/zh active Pending
- 2021-07-29 IL IL299811A patent/IL299811A/en unknown
- 2021-07-29 FI FIEP21752123.6T patent/FI4118200T3/fi active
- 2021-07-29 BR BR112023001583A patent/BR112023001583A2/pt unknown
- 2021-07-29 AU AU2021316875A patent/AU2021316875B2/en active Active
- 2021-07-29 EP EP25199900.9A patent/EP4643868A3/en active Pending