JP2023535073A - ジストロフィン異常症を処置するための筋標的化複合体およびそれらの使用 - Google Patents

ジストロフィン異常症を処置するための筋標的化複合体およびそれらの使用 Download PDF

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JP2023535073A
JP2023535073A JP2023504634A JP2023504634A JP2023535073A JP 2023535073 A JP2023535073 A JP 2023535073A JP 2023504634 A JP2023504634 A JP 2023504634A JP 2023504634 A JP2023504634 A JP 2023504634A JP 2023535073 A JP2023535073 A JP 2023535073A
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seq
amino acid
acid sequence
antibody
light chain
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JPWO2022020107A5 (enExample
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サブラマニアン，ロメシュ，アール．
カタナニ，モハマド，ティー．
ウィーデン，ティモシー
デジャルダン，コディ，エー．
クイン，ブレンダン
ナジム，ジョン
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Dyne Therapeutics Inc
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Dyne Therapeutics Inc
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JP2023504634A 2020-07-23 2021-07-09 ジストロフィン異常症を処置するための筋標的化複合体およびそれらの使用 Pending JP2023535073A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202063055777P 2020-07-23 2020-07-23
US63/055,777 2020-07-23
US202063069077P 2020-08-23 2020-08-23
US63/069,077 2020-08-23
US202163143829P 2021-01-30 2021-01-30
US63/143,829 2021-01-30
PCT/US2021/040998 WO2022020107A1 (en) 2020-07-23 2021-07-09 Muscle targeting complexes and uses thereof for treating dystrophinopathies

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JP2023535073A true JP2023535073A (ja) 2023-08-15
JPWO2022020107A5 JPWO2022020107A5 (enExample) 2024-07-18

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US (1) US20230285586A1 (enExample)
EP (1) EP4185330A4 (enExample)
JP (1) JP2023535073A (enExample)
KR (1) KR20230044242A (enExample)
CN (1) CN116368150A (enExample)
AU (1) AU2021312709A1 (enExample)
BR (1) BR112023001125A2 (enExample)
CA (1) CA3186752A1 (enExample)
IL (1) IL299662A (enExample)
MX (1) MX2023000984A (enExample)
WO (1) WO2022020107A1 (enExample)

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US12097263B2 (en) 2018-08-02 2024-09-24 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
WO2020028832A1 (en) 2018-08-02 2020-02-06 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US12370264B1 (en) 2018-08-02 2025-07-29 Dyne Therapeutics, Inc. Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject
US20220193250A1 (en) 2018-08-02 2022-06-23 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US11168141B2 (en) 2018-08-02 2021-11-09 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11911484B2 (en) 2018-08-02 2024-02-27 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
EP3959319A4 (en) 2019-04-25 2023-06-07 Avidity Biosciences, Inc. NUCLEIC ACID COMPOSITIONS AND METHODS FOR MULTI-EXON SKIPPING
CN116194470B (zh) * 2020-07-23 2025-10-03 达因疗法公司 肌肉靶向复合物及其用途
CN116744943A (zh) * 2020-12-04 2023-09-12 达因疗法公司 抗体-寡核苷酸复合物及其用途
MX2023014417A (es) 2021-06-23 2023-12-15 Nippon Shinyaku Co Ltd Combinacion de oligomeros antisentido.
KR20240035826A (ko) * 2021-07-09 2024-03-18 다인 세라퓨틱스, 인크. 근육 표적화 복합체 및 디스트로핀병증을 치료하기 위한 그의 용도
IL309911A (en) * 2021-07-09 2024-03-01 Dyne Therapeutics Inc Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11638761B2 (en) 2021-07-09 2023-05-02 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy
EP4366784A1 (en) 2021-07-09 2024-05-15 Dyne Therapeutics, Inc. Muscle targeting complexes and formulations for treating dystrophinopathies
US11771776B2 (en) 2021-07-09 2023-10-03 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
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