|
US4217344A
(en)
|
1976-06-23 |
1980-08-12 |
L'oreal |
Compositions containing aqueous dispersions of lipid spheres
|
|
US4196265A
(en)
|
1977-06-15 |
1980-04-01 |
The Wistar Institute |
Method of producing antibodies
|
|
US4235871A
(en)
|
1978-02-24 |
1980-11-25 |
Papahadjopoulos Demetrios P |
Method of encapsulating biologically active materials in lipid vesicles
|
|
US4186183A
(en)
|
1978-03-29 |
1980-01-29 |
The United States Of America As Represented By The Secretary Of The Army |
Liposome carriers in chemotherapy of leishmaniasis
|
|
US4261975A
(en)
|
1979-09-19 |
1981-04-14 |
Merck & Co., Inc. |
Viral liposome particle
|
|
US4485054A
(en)
|
1982-10-04 |
1984-11-27 |
Lipoderm Pharmaceuticals Limited |
Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV)
|
|
US4501728A
(en)
|
1983-01-06 |
1985-02-26 |
Technology Unlimited, Inc. |
Masking of liposomes from RES recognition
|
|
US5380831A
(en)
|
1986-04-04 |
1995-01-10 |
Mycogen Plant Science, Inc. |
Synthetic insecticidal crystal protein gene
|
|
US4946787A
(en)
|
1985-01-07 |
1990-08-07 |
Syntex (U.S.A.) Inc. |
N-(ω,(ω-1)-dialkyloxy)- and N-(ω,(ω-1)-dialkenyloxy)-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
|
|
US4897355A
(en)
|
1985-01-07 |
1990-01-30 |
Syntex (U.S.A.) Inc. |
N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
|
|
US5049386A
(en)
|
1985-01-07 |
1991-09-17 |
Syntex (U.S.A.) Inc. |
N-ω,(ω-1)-dialkyloxy)- and N-(ω,(ω-1)-dialkenyloxy)Alk-1-YL-N,N,N-tetrasubstituted ammonium lipids and uses therefor
|
|
US4797368A
(en)
|
1985-03-15 |
1989-01-10 |
The United States Of America As Represented By The Department Of Health And Human Services |
Adeno-associated virus as eukaryotic expression vector
|
|
US5569597A
(en)
|
1985-05-13 |
1996-10-29 |
Ciba Geigy Corp. |
Methods of inserting viral DNA into plant material
|
|
US4774085A
(en)
|
1985-07-09 |
1988-09-27 |
501 Board of Regents, Univ. of Texas |
Pharmaceutical administration systems containing a mixture of immunomodulators
|
|
US4853331A
(en)
|
1985-08-16 |
1989-08-01 |
Mycogen Corporation |
Cloning and expression of Bacillus thuringiensis toxin gene toxic to beetles of the order Coleoptera
|
|
US5268463A
(en)
|
1986-11-11 |
1993-12-07 |
Jefferson Richard A |
Plant promoter α-glucuronidase gene construct
|
|
US5608142A
(en)
|
1986-12-03 |
1997-03-04 |
Agracetus, Inc. |
Insecticidal cotton plants
|
|
US4837028A
(en)
|
1986-12-24 |
1989-06-06 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
|
US5039523A
(en)
|
1988-10-27 |
1991-08-13 |
Mycogen Corporation |
Novel Bacillus thuringiensis isolate denoted B.t. PS81F, active against lepidopteran pests, and a gene encoding a lepidopteran-active toxin
|
|
KR920701453A
(ko)
|
1989-03-17 |
1992-08-11 |
미리엄 디. 멕코나헤이 |
유전자발현의 외부조절
|
|
ES2187497T3
(es)
|
1990-04-12 |
2003-06-16 |
Syngenta Participations Ag |
Promotores preferentemente en tejidos.
|
|
US5264618A
(en)
|
1990-04-19 |
1993-11-23 |
Vical, Inc. |
Cationic lipids for intracellular delivery of biologically active molecules
|
|
AU7979491A
(en)
|
1990-05-03 |
1991-11-27 |
Vical, Inc. |
Intracellular delivery of biologically active substances by means of self-assembling lipid complexes
|
|
US5498830A
(en)
|
1990-06-18 |
1996-03-12 |
Monsanto Company |
Decreased oil content in plant seeds
|
|
CA2051562C
(en)
|
1990-10-12 |
2003-12-02 |
Jewel M. Payne |
Bacillus thuringiensis isolates active against dipteran pests
|
|
US5173414A
(en)
|
1990-10-30 |
1992-12-22 |
Applied Immune Sciences, Inc. |
Production of recombinant adeno-associated virus vectors
|
|
US5399680A
(en)
|
1991-05-22 |
1995-03-21 |
The Salk Institute For Biological Studies |
Rice chitinase promoter
|
|
JPH06510187A
(ja)
|
1991-08-27 |
1994-11-17 |
ノバルティス アクチエンゲゼルシャフト |
同翅類昆虫に対する殺虫性質を有したタンパク質及び植物保護におけるそれらの用法
|
|
TW261517B
(enExample)
|
1991-11-29 |
1995-11-01 |
Mitsubishi Shozi Kk |
|
|
US5587308A
(en)
|
1992-06-02 |
1996-12-24 |
The United States Of America As Represented By The Department Of Health & Human Services |
Modified adeno-associated virus vector capable of expression from a novel promoter
|
|
US5789156A
(en)
|
1993-06-14 |
1998-08-04 |
Basf Ag |
Tetracycline-regulated transcriptional inhibitors
|
|
US5814618A
(en)
|
1993-06-14 |
1998-09-29 |
Basf Aktiengesellschaft |
Methods for regulating gene expression
|
|
US5837458A
(en)
|
1994-02-17 |
1998-11-17 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
|
US5605793A
(en)
|
1994-02-17 |
1997-02-25 |
Affymax Technologies N.V. |
Methods for in vitro recombination
|
|
US5608144A
(en)
|
1994-08-12 |
1997-03-04 |
Dna Plant Technology Corp. |
Plant group 2 promoters and uses thereof
|
|
US5659026A
(en)
|
1995-03-24 |
1997-08-19 |
Pioneer Hi-Bred International |
ALS3 promoter
|
|
US6072050A
(en)
|
1996-06-11 |
2000-06-06 |
Pioneer Hi-Bred International, Inc. |
Synthetic promoters
|
|
US6380370B1
(en)
*
|
1997-08-14 |
2002-04-30 |
Genome Therapeutics Corporation |
Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics
|
|
ES2270227T3
(es)
|
1998-02-26 |
2007-04-01 |
Pioneer Hi-Bred International, Inc. |
Promotor met-1 del maiz.
|
|
US6534261B1
(en)
|
1999-01-12 |
2003-03-18 |
Sangamo Biosciences, Inc. |
Regulation of endogenous gene expression in cells using zinc finger proteins
|
|
CN1360632A
(zh)
|
1999-05-04 |
2002-07-24 |
孟山都技术有限公司 |
鞘翅目毒性多肽组合物和抗虫转基因植物
|
|
BR0014516A
(pt)
|
1999-09-15 |
2002-07-02 |
Monsanto Technology Llc |
Composições e métodos de uso de delta-endotoxina do bacilo thuringiensis ativo de lepidopteran
|
|
US20050183161A1
(en)
|
2003-10-14 |
2005-08-18 |
Athenix Corporation |
AXMI-010, a delta-endotoxin gene and methods for its use
|
|
US7629504B2
(en)
|
2003-12-22 |
2009-12-08 |
Pioneer Hi-Bred International, Inc. |
Bacillus thuringiensis cry9 nucleic acids
|
|
ES2397118T3
(es)
|
2006-06-14 |
2013-03-04 |
Athenix Corporation |
AXMI-031, AXMI-039 ,AXMI-040 y AXMI-049, una familia de genes de endotoxina delta y métodos para su uso
|
|
CN102648281B
(zh)
|
2009-07-02 |
2017-04-05 |
阿森尼克斯公司 |
Axmi‑205杀虫基因和它的使用方法
|
|
US8586832B2
(en)
|
2009-12-21 |
2013-11-19 |
Pioneer Hi Bred International Inc |
Bacillus thuringiensis gene with Lepidopteran activity
|
|
CN103154247A
(zh)
|
2010-08-19 |
2013-06-12 |
先锋国际良种公司 |
对鳞翅目昆虫具有活性的新苏云金杆菌基因
|
|
US9405700B2
(en)
|
2010-11-04 |
2016-08-02 |
Sonics, Inc. |
Methods and apparatus for virtualization in an integrated circuit
|
|
ES2728782T3
(es)
|
2012-05-25 |
2019-10-28 |
Univ California |
Métodos y composiciones para la modificación de ADN objetivo dirigida por ARN y para la modulación de la transcripción dirigida por ARN
|
|
US10450584B2
(en)
|
2014-08-28 |
2019-10-22 |
North Carolina State University |
Cas9 proteins and guiding features for DNA targeting and genome editing
|
|
US9790490B2
(en)
|
2015-06-18 |
2017-10-17 |
The Broad Institute Inc. |
CRISPR enzymes and systems
|
|
EP3676376B1
(en)
*
|
2017-08-30 |
2025-01-15 |
President and Fellows of Harvard College |
High efficiency base editors comprising gam
|
|
AU2019282149B2
(en)
|
2018-06-05 |
2025-08-21 |
Life Edit Therapeutics, Inc. |
RNA-guided nucleases and active fragments and variants thereof and methods of use
|
|
CN113631704A
(zh)
|
2018-12-27 |
2021-11-09 |
生命编辑制药股份有限公司 |
可用于基因编辑的多肽及使用方法
|
|
CN118813654A
(zh)
|
2019-08-12 |
2024-10-22 |
生命编辑制药股份有限公司 |
Rna指导的核酸酶及其活性片段及变体以及使用方法
|
|
EP4085133A1
(en)
|
2019-12-30 |
2022-11-09 |
Lifeedit Therapeutics, Inc. |
Rna-guided nucleases and active fragments and variants thereof and methods of use
|