JP2023534636A5 - - Google Patents
Info
- Publication number
- JP2023534636A5 JP2023534636A5 JP2023501003A JP2023501003A JP2023534636A5 JP 2023534636 A5 JP2023534636 A5 JP 2023534636A5 JP 2023501003 A JP2023501003 A JP 2023501003A JP 2023501003 A JP2023501003 A JP 2023501003A JP 2023534636 A5 JP2023534636 A5 JP 2023534636A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- wild
- acid substitution
- position corresponding
- type cat
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2026064109A JP2026126235A (ja) | 2020-07-10 | 2026-04-09 | 治療薬のネコにおける半減期を増加させるための組成物及びその使用方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063050535P | 2020-07-10 | 2020-07-10 | |
| US63/050,535 | 2020-07-10 | ||
| US202163143720P | 2021-01-29 | 2021-01-29 | |
| US63/143,720 | 2021-01-29 | ||
| PCT/US2021/038714 WO2022010652A1 (en) | 2020-07-10 | 2021-06-23 | Compositions for increasing half-life of a therapeutic agent in felines and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2026064109A Division JP2026126235A (ja) | 2020-07-10 | 2026-04-09 | 治療薬のネコにおける半減期を増加させるための組成物及びその使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023534636A JP2023534636A (ja) | 2023-08-10 |
| JP2023534636A5 true JP2023534636A5 (enExample) | 2024-07-01 |
| JP7881538B2 JP7881538B2 (ja) | 2026-06-29 |
Family
ID=77043030
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023501003A Active JP7881538B2 (ja) | 2020-07-10 | 2021-06-23 | 治療薬のネコにおける半減期を増加させるための組成物及びその使用方法 |
| JP2026064109A Pending JP2026126235A (ja) | 2020-07-10 | 2026-04-09 | 治療薬のネコにおける半減期を増加させるための組成物及びその使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2026064109A Pending JP2026126235A (ja) | 2020-07-10 | 2026-04-09 | 治療薬のネコにおける半減期を増加させるための組成物及びその使用方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US11498953B2 (enExample) |
| EP (1) | EP4178977A1 (enExample) |
| JP (2) | JP7881538B2 (enExample) |
| KR (1) | KR20230038522A (enExample) |
| CN (2) | CN116096741B (enExample) |
| AU (1) | AU2021306179A1 (enExample) |
| BR (1) | BR112022027028A2 (enExample) |
| CA (1) | CA3188448A1 (enExample) |
| MX (1) | MX2023000500A (enExample) |
| TW (1) | TW202216749A (enExample) |
| WO (1) | WO2022010652A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10093731B2 (en) | 2017-02-24 | 2018-10-09 | Kindred Biosciences, Inc. | Anti-IL31 antibodies for veterinary use |
| AU2018318440A1 (en) | 2017-08-15 | 2020-02-13 | Kindred Biosciences, Inc. | IgG Fc variants for veterinary use |
| CN120005022A (zh) | 2019-01-03 | 2025-05-16 | 因外泰克斯公司 | 用于增加治疗剂在犬中的半衰期的组合物及使用方法 |
| JP7671275B2 (ja) | 2019-08-29 | 2025-05-01 | エランコ・ユーエス・インコーポレイテッド | 動物用の抗il31抗体 |
| JP7832123B2 (ja) | 2020-05-11 | 2026-03-17 | インベテックス インコーポレイテッド | 治療薬のイヌにおける半減期を増加させるための組成物及びその使用方法 |
| EP4166574A4 (en) * | 2020-06-10 | 2025-01-15 | Bica Therapeutics Inc. | FUSION PROTEIN WITH ERYTHROPOIETIN POLYPEPTIDE |
| CN116096741B (zh) | 2020-07-10 | 2024-10-18 | 因外泰克斯公司 | 用于延长治疗剂在猫科动物中的半衰期的组合物和使用方法 |
| EP4255933A4 (en) * | 2020-12-07 | 2025-07-23 | Invetx Inc | COMPOSITIONS FOR INCREASING THE HALF-LIFE OF A THERAPEUTIC AGENT IN LIVESTOCK ANIMALS AND METHODS OF USE |
| US20240400708A1 (en) * | 2020-12-18 | 2024-12-05 | Zoetis Services Llc | Mutations in feline antibody constant regions |
| AU2023415535A1 (en) | 2022-12-27 | 2025-07-10 | Invetx, Inc. | Polypeptides with altered binding to neonatal fc receptor (fcrn) and methods of use |
| CN121002059A (zh) | 2023-01-20 | 2025-11-21 | 因外泰克斯公司 | 用于伴侣动物的双特异性结合剂 |
| IL322604A (en) * | 2023-02-08 | 2025-10-01 | Levicept Ltd | Fusion protein |
| EP4669757A1 (en) | 2024-03-21 | 2025-12-31 | Akston Biosciences Corporation | PD-L1 ANALOGUE FUSION PROTEINS FOR ANTIGEN-SPECIFIC IMMUNOTHERAPY AND METHODS OF USE |
| CN121779581B (zh) * | 2026-03-09 | 2026-06-16 | 华中农业大学 | 长效猫粒细胞巨噬细胞集落刺激因子重组蛋白、及其cho细胞表达方法和应用 |
Family Cites Families (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4447233A (en) | 1981-04-10 | 1984-05-08 | Parker-Hannifin Corporation | Medication infusion pump |
| US4439196A (en) | 1982-03-18 | 1984-03-27 | Merck & Co., Inc. | Osmotic drug delivery system |
| US4447224A (en) | 1982-09-20 | 1984-05-08 | Infusaid Corporation | Variable flow implantable infusion apparatus |
| US4487603A (en) | 1982-11-26 | 1984-12-11 | Cordis Corporation | Implantable microinfusion pump system |
| US5683888A (en) | 1989-07-22 | 1997-11-04 | University Of Wales College Of Medicine | Modified bioluminescent proteins and their use |
| US5292658A (en) | 1989-12-29 | 1994-03-08 | University Of Georgia Research Foundation, Inc. Boyd Graduate Studies Research Center | Cloning and expressions of Renilla luciferase |
| DK0575319T3 (da) | 1991-03-11 | 2000-07-10 | Univ Georgia Res Found | Kloning og ekspression af Renilla-luciferase |
| CA2169298A1 (en) | 1993-09-10 | 1995-03-16 | Martin Chalfie | Uses of green fluorescent protein |
| WO1995021191A1 (en) | 1994-02-04 | 1995-08-10 | William Ward | Bioluminescent indicator based upon the expression of a gene for a modified green-fluorescent protein |
| US5777079A (en) | 1994-11-10 | 1998-07-07 | The Regents Of The University Of California | Modified green fluorescent proteins |
| US5874304A (en) | 1996-01-18 | 1999-02-23 | University Of Florida Research Foundation, Inc. | Humanized green fluorescent protein genes and methods |
| US5804387A (en) | 1996-02-01 | 1998-09-08 | The Board Of Trustees Of The Leland Stanford Junior University | FACS-optimized mutants of the green fluorescent protein (GFP) |
| US5876995A (en) | 1996-02-06 | 1999-03-02 | Bryan; Bruce | Bioluminescent novelty items |
| US5925558A (en) | 1996-07-16 | 1999-07-20 | The Regents Of The University Of California | Assays for protein kinases using fluorescent protein substrates |
| US5976796A (en) | 1996-10-04 | 1999-11-02 | Loma Linda University | Construction and expression of renilla luciferase and green fluorescent protein fusion genes |
| ATE290205T1 (de) | 1996-12-12 | 2005-03-15 | Prolume Ltd | Vorrichtung und verfahren zum nachweis und identifizieren von infektiösen wirkstoffen |
| AU765703B2 (en) | 1998-03-27 | 2003-09-25 | Bruce J. Bryan | Luciferases, fluorescent proteins, nucleic acids encoding the luciferases and fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items |
| US7658921B2 (en) | 2000-12-12 | 2010-02-09 | Medimmune, Llc | Molecules with extended half-lives, compositions and uses thereof |
| WO2005047327A2 (en) | 2003-11-12 | 2005-05-26 | Biogen Idec Ma Inc. | NEONATAL Fc RECEPTOR (FcRn)-BINDING POLYPEPTIDE VARIANTS, DIMERIC Fc BINDING PROTEINS AND METHODS RELATED THERETO |
| BRPI0514068B8 (pt) * | 2004-08-04 | 2021-05-25 | Applied Molecular Evolution Inc | anticorpo anti-cd20, e, composição farmacêutica |
| CA2577133A1 (en) | 2004-08-19 | 2006-03-23 | Genentech, Inc. | Polypeptide variants with altered effector function |
| US8546543B2 (en) * | 2004-11-12 | 2013-10-01 | Xencor, Inc. | Fc variants that extend antibody half-life |
| CN101098890B (zh) * | 2004-11-12 | 2012-07-18 | 赞科股份有限公司 | 对FcRn的结合被改变的Fc变体 |
| US8802820B2 (en) * | 2004-11-12 | 2014-08-12 | Xencor, Inc. | Fc variants with altered binding to FcRn |
| WO2010110838A2 (en) | 2009-03-25 | 2010-09-30 | Vet Therapeutics Inc. | Antibody constant domain regions and uses thereof |
| WO2010117448A2 (en) | 2009-04-05 | 2010-10-14 | Provenance Biopharmaceuticals Corp. | Chimeric immunocytokines and methods of use thereof |
| AU2012252152B2 (en) | 2011-05-06 | 2016-07-07 | Zoetis Services Llc | Anti-nerve growth factor antibodies and methods of preparing and using the same |
| US8790651B2 (en) | 2011-07-21 | 2014-07-29 | Zoetis Llc | Interleukin-31 monoclonal antibody |
| US20130129727A1 (en) | 2011-11-17 | 2013-05-23 | Nanjingjinsirui Science & Technology Biology Corporation | Methods and systems for increasing protein stability |
| US20140294812A1 (en) * | 2013-03-15 | 2014-10-02 | Xencor, Inc. | Fc variants that improve fcrn binding and/or increase antibody half-life |
| WO2016044676A2 (en) * | 2014-09-18 | 2016-03-24 | AskGene Pharma, Inc. | Novel feline erythropoietin receptor agonists |
| US11596699B2 (en) | 2016-04-29 | 2023-03-07 | CureVac SE | RNA encoding an antibody |
| EP3481413A4 (en) | 2016-07-08 | 2020-01-08 | Askgene Pharma, Inc. | FUSION PROTEIN WITH LEPTIN AND METHOD FOR THE PRODUCTION AND USE THEREOF |
| EP3526246A1 (en) * | 2016-10-17 | 2019-08-21 | Vetoquinol SA | Modified antibody constant region |
| US10093731B2 (en) | 2017-02-24 | 2018-10-09 | Kindred Biosciences, Inc. | Anti-IL31 antibodies for veterinary use |
| AU2018318440A1 (en) | 2017-08-15 | 2020-02-13 | Kindred Biosciences, Inc. | IgG Fc variants for veterinary use |
| BR112020017701A2 (pt) | 2018-03-12 | 2020-12-29 | Zoetis Services Llc | Anticorpos anti-ngf e métodos dos mesmos |
| JP7449234B2 (ja) | 2018-03-16 | 2024-03-13 | ゾエティス・サービシーズ・エルエルシー | 獣医学使用のためのインターロイキン31モノクローナル抗体 |
| JP2022500037A (ja) | 2018-09-14 | 2022-01-04 | キンドレッド バイオサイエンシズ インコーポレイテッド | 獣医学的使用のための抗il4受容体抗体 |
| EP3866842A4 (en) | 2018-10-18 | 2022-07-13 | Kindred Biosciences, Inc. | FC VARIANTS WITH MODIFIED BINDING TO THE NEONATAL FC RECEPTOR (FCRN) FOR VETERINARY USE |
| WO2020116560A1 (ja) * | 2018-12-05 | 2020-06-11 | 株式会社バイカ・セラピュティクス | 抗体のFc領域改変体 |
| WO2020139984A1 (en) | 2018-12-27 | 2020-07-02 | Kindred Biosciences, Inc. | Igg fc variants for veterinary use |
| CN120005022A (zh) * | 2019-01-03 | 2025-05-16 | 因外泰克斯公司 | 用于增加治疗剂在犬中的半衰期的组合物及使用方法 |
| CN115135669B (zh) | 2020-02-19 | 2026-05-19 | 硕腾服务有限责任公司 | 修饰的Fc区 |
| IL297287A (en) | 2020-04-17 | 2022-12-01 | Zoetis Services Llc | Canine antibody variants |
| EP4136109A1 (en) | 2020-04-17 | 2023-02-22 | Zoetis Services LLC | Feline antibody variants |
| JP7832123B2 (ja) | 2020-05-11 | 2026-03-17 | インベテックス インコーポレイテッド | 治療薬のイヌにおける半減期を増加させるための組成物及びその使用方法 |
| US20220119513A1 (en) | 2020-06-08 | 2022-04-21 | Zoetis Services Llc | Anti-tgfb antibodies and therapeutic uses thereof |
| CN116096741B (zh) | 2020-07-10 | 2024-10-18 | 因外泰克斯公司 | 用于延长治疗剂在猫科动物中的半衰期的组合物和使用方法 |
| KR20230104157A (ko) | 2020-10-07 | 2023-07-07 | 조에티스 서비시즈 엘엘씨 | 항-ngf 항체 및 그의 사용 방법 |
| TW202607038A (zh) | 2020-10-19 | 2026-02-16 | 美商碩騰服務公司 | 犬及貓抑瘤素M受體β之抗體及其用途 |
| US20240400708A1 (en) | 2020-12-18 | 2024-12-05 | Zoetis Services Llc | Mutations in feline antibody constant regions |
| US20250011410A1 (en) | 2021-11-23 | 2025-01-09 | Invetx, Inc. | Anti-ngf antibodies and uses thereof |
-
2021
- 2021-06-23 CN CN202180056036.XA patent/CN116096741B/zh active Active
- 2021-06-23 EP EP21745871.0A patent/EP4178977A1/en active Pending
- 2021-06-23 KR KR1020237004652A patent/KR20230038522A/ko active Pending
- 2021-06-23 WO PCT/US2021/038714 patent/WO2022010652A1/en not_active Ceased
- 2021-06-23 US US17/355,839 patent/US11498953B2/en active Active
- 2021-06-23 AU AU2021306179A patent/AU2021306179A1/en active Pending
- 2021-06-23 BR BR112022027028A patent/BR112022027028A2/pt unknown
- 2021-06-23 CA CA3188448A patent/CA3188448A1/en active Pending
- 2021-06-23 CN CN202411349658.3A patent/CN119899259A/zh active Pending
- 2021-06-23 JP JP2023501003A patent/JP7881538B2/ja active Active
- 2021-06-23 MX MX2023000500A patent/MX2023000500A/es unknown
- 2021-07-02 TW TW110124393A patent/TW202216749A/zh unknown
-
2022
- 2022-04-29 US US17/733,479 patent/US11739135B2/en active Active
- 2022-10-12 US US18/046,082 patent/US12344650B2/en active Active
-
2025
- 2025-06-09 US US19/232,626 patent/US20250304650A1/en active Pending
-
2026
- 2026-04-09 JP JP2026064109A patent/JP2026126235A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023526225A5 (enExample) | ||
| AU2022218544B2 (en) | Hetero-dimeric multi-specific antibody format | |
| WO2020142625A4 (en) | Compositions for increasing half-life of a therapeutic agent in canines and methods of use | |
| JP7264383B2 (ja) | 血中半減期の向上のための抗体Fc変異体 | |
| JP6385357B2 (ja) | 抗体重鎖不変部位の異種二量体、高効率の形成を誘導するch3ドメイン変異体対、その作製方法および用途 | |
| Bringman et al. | Monoclonal antibodies to human tumor necrosis factors alpha and beta: application for affinity purification, immunoassays, and as structural probes | |
| WO2005040217B1 (en) | Antibodies having a mutated amino acid residue at position 268 (ch2 region) in constant regions | |
| CN118063619A (zh) | 工程化的异源二聚体蛋白质 | |
| US11401299B2 (en) | Generating multispecific antibody mixtures and methods of uses thereof | |
| WO2020209318A1 (ja) | Fc領域改変抗体の精製方法 | |
| KR102382593B1 (ko) | pH-감응성 Fc 변이체 | |
| JP7634545B2 (ja) | pH感応性FC変異体 | |
| JP2023553694A5 (enExample) | ||
| JP2024531346A5 (enExample) | ||
| CN119487073A (zh) | 一种抗体及其用途 | |
| Abraha et al. | The preparation and characterization of monoclonal antibodies to human complement component C8 and their use in purification of C8 and C8 subunits | |
| JP2023552456A5 (enExample) | ||
| AU674523B2 (en) | An interferon-alpha/beta binding protein its preparation and pharmaceutical compositions containing it | |
| CN117264054B (zh) | 靶向il-6的纳米抗体、组合物、方法及用途 | |
| AU2020270242B2 (en) | Anti-TNF-α humanized monoclonal antibody TCX060 having low immunogenicity and low ADCC/CDC function, and use thereof | |
| JP2024522092A5 (enExample) | ||
| CN115246885B (zh) | 一种双特异性抗体及其应用 | |
| JP2019172702A (ja) | 目的とする含量で不純物を含むTNFR−Fc融合タンパク質の製造方法 | |
| JP2024546916A5 (enExample) | ||
| JP2023525555A5 (enExample) |