JP2023534009A5 - - Google Patents
Info
- Publication number
- JP2023534009A5 JP2023534009A5 JP2023501802A JP2023501802A JP2023534009A5 JP 2023534009 A5 JP2023534009 A5 JP 2023534009A5 JP 2023501802 A JP2023501802 A JP 2023501802A JP 2023501802 A JP2023501802 A JP 2023501802A JP 2023534009 A5 JP2023534009 A5 JP 2023534009A5
- Authority
- JP
- Japan
- Prior art keywords
- agent according
- raf
- administered
- antibody
- approximately
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063051320P | 2020-07-13 | 2020-07-13 | |
| US63/051,320 | 2020-07-13 | ||
| PCT/US2021/041439 WO2022015736A1 (en) | 2020-07-13 | 2021-07-13 | Combination therapy for treating abnormal cell growth |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023534009A JP2023534009A (ja) | 2023-08-07 |
| JP2023534009A5 true JP2023534009A5 (enExample) | 2024-07-23 |
Family
ID=79554253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023501802A Pending JP2023534009A (ja) | 2020-07-13 | 2021-07-13 | 異常な細胞成長を処置するための併用療法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230330088A1 (enExample) |
| EP (1) | EP4178573A4 (enExample) |
| JP (1) | JP2023534009A (enExample) |
| KR (1) | KR20230039684A (enExample) |
| CN (1) | CN116056699A (enExample) |
| AU (1) | AU2021307410A1 (enExample) |
| BR (1) | BR112023000675A2 (enExample) |
| CA (1) | CA3189383A1 (enExample) |
| IL (1) | IL299789A (enExample) |
| MX (1) | MX2023000589A (enExample) |
| WO (1) | WO2022015736A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2021206684B2 (en) | 2020-01-10 | 2024-01-18 | Immuneering Corporation | MEK inhibitors and therapeutic uses thereof |
| WO2023138630A1 (zh) * | 2022-01-21 | 2023-07-27 | 应世生物科技(南京)有限公司 | 治疗肿瘤的药物组合及用途 |
| CN116120461B (zh) * | 2022-04-29 | 2023-09-29 | 德琪(杭州)生物有限公司 | 新型抗药抗体以及其用途 |
| US11873296B2 (en) | 2022-06-07 | 2024-01-16 | Verastem, Inc. | Solid forms of a dual RAF/MEK inhibitor |
| CN119947725A (zh) * | 2022-09-30 | 2025-05-06 | 应世生物科技(南京)有限公司 | Fak抑制剂及诱导免疫原性细胞死亡的物质的药物组合及用途 |
| WO2024178274A2 (en) * | 2023-02-24 | 2024-08-29 | Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center | Methods of degrading raf(raf) protein in cells using mitogen-activated protein kinase kinase 1/2 (mek1/2) protein degraders |
| TW202508595A (zh) | 2023-05-04 | 2025-03-01 | 美商銳新醫藥公司 | 用於ｒａｓ相關疾病或病症之組合療法 |
| US20250049810A1 (en) | 2023-08-07 | 2025-02-13 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| AU2024360465A1 (en) | 2023-10-12 | 2026-04-09 | Revolution Medicines, Inc. | Macrocyclic ras inhibitors |
| WO2025079712A1 (ja) * | 2023-10-12 | 2025-04-17 | 中外製薬株式会社 | ドライバー変異を有するがん患者における分子標的薬併用療法 |
| WO2025171296A1 (en) | 2024-02-09 | 2025-08-14 | Revolution Medicines, Inc. | Ras inhibitors |
| TW202547461A (zh) | 2024-05-17 | 2025-12-16 | 美商銳新醫藥公司 | Ｒａｓ抑制劑 |
| WO2025255438A1 (en) | 2024-06-07 | 2025-12-11 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2025265060A1 (en) | 2024-06-21 | 2025-12-26 | Revolution Medicines, Inc. | Therapeutic compositions and methods for managing treatment-related effects |
| WO2026006747A1 (en) | 2024-06-28 | 2026-01-02 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026015801A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015790A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015796A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015825A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Use of ras inhibitor for treating pancreatic cancer |
| WO2026050446A1 (en) | 2024-08-29 | 2026-03-05 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026072904A2 (en) | 2024-09-26 | 2026-04-02 | Revolution Medicines, Inc. | Compositions and methods for treating lung cancer |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX368257B (es) * | 2011-08-01 | 2019-09-26 | Genentech Inc | Antagonistas de unión al eje pd-1e inhibidores de mek y sus usos en el tratamiento de cáncer. |
| WO2015120289A1 (en) * | 2014-02-07 | 2015-08-13 | Verastem, Inc. | Methods and compositions for treating abnormal cell growth |
| US20170112865A1 (en) * | 2014-05-21 | 2017-04-27 | The Board Of Regents Of The University Of Texas System | Treatment for melanoma |
| EP3563870A1 (en) * | 2014-07-15 | 2019-11-06 | F. Hoffmann-La Roche AG | Methods of treating cancer using pd-1 axis binding antagonists and mek inhibitors |
| US10532056B2 (en) * | 2015-06-29 | 2020-01-14 | Verastem, Inc. | Therapeutic compositions, combinations, and methods of use |
| CN109663130B (zh) * | 2017-10-13 | 2021-06-29 | 江苏恒瑞医药股份有限公司 | Pd-1抗体和mek抑制剂联合在制备治疗肿瘤的药物中的用途 |
| JP2022547358A (ja) * | 2019-09-13 | 2022-11-14 | ジ インスティテュート オブ キャンサー リサーチ：ロイヤル キャンサー ホスピタル | 治療組成物、組み合わせ、及び使用方法 |
-
2021
- 2021-07-13 BR BR112023000675A patent/BR112023000675A2/pt unknown
- 2021-07-13 KR KR1020237004543A patent/KR20230039684A/ko active Pending
- 2021-07-13 AU AU2021307410A patent/AU2021307410A1/en active Pending
- 2021-07-13 MX MX2023000589A patent/MX2023000589A/es unknown
- 2021-07-13 CA CA3189383A patent/CA3189383A1/en active Pending
- 2021-07-13 CN CN202180049487.0A patent/CN116056699A/zh active Pending
- 2021-07-13 IL IL299789A patent/IL299789A/en unknown
- 2021-07-13 US US18/005,012 patent/US20230330088A1/en active Pending
- 2021-07-13 EP EP21841921.6A patent/EP4178573A4/en active Pending
- 2021-07-13 WO PCT/US2021/041439 patent/WO2022015736A1/en not_active Ceased
- 2021-07-13 JP JP2023501802A patent/JP2023534009A/ja active Pending
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