JP2023532985A5 - - Google Patents

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Publication number
JP2023532985A5
JP2023532985A5 JP2023500279A JP2023500279A JP2023532985A5 JP 2023532985 A5 JP2023532985 A5 JP 2023532985A5 JP 2023500279 A JP2023500279 A JP 2023500279A JP 2023500279 A JP2023500279 A JP 2023500279A JP 2023532985 A5 JP2023532985 A5 JP 2023532985A5
Authority
JP
Japan
Prior art keywords
alkyl
group
alkoxy
cycloalkyl
epilepsy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023500279A
Other languages
English (en)
Japanese (ja)
Other versions
JP7824664B2 (ja
JP2023532985A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/040486 external-priority patent/WO2022010880A1/en
Publication of JP2023532985A publication Critical patent/JP2023532985A/ja
Publication of JP2023532985A5 publication Critical patent/JP2023532985A5/ja
Application granted granted Critical
Publication of JP7824664B2 publication Critical patent/JP7824664B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2023500279A 2020-07-06 2021-07-06 Kcnt1阻害剤及び使用方法 Active JP7824664B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063048335P 2020-07-06 2020-07-06
US63/048,335 2020-07-06
PCT/US2021/040486 WO2022010880A1 (en) 2020-07-06 2021-07-06 Kcnt1 inhibitors and methods of use

Publications (3)

Publication Number Publication Date
JP2023532985A JP2023532985A (ja) 2023-08-01
JP2023532985A5 true JP2023532985A5 (enExample) 2024-07-11
JP7824664B2 JP7824664B2 (ja) 2026-03-05

Family

ID=79552679

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023500279A Active JP7824664B2 (ja) 2020-07-06 2021-07-06 Kcnt1阻害剤及び使用方法

Country Status (10)

Country Link
US (1) US20230219921A1 (enExample)
EP (1) EP4175624A4 (enExample)
JP (1) JP7824664B2 (enExample)
KR (1) KR20230035608A (enExample)
CN (1) CN116075297A (enExample)
AU (1) AU2021305058A1 (enExample)
CA (1) CA3188825A1 (enExample)
IL (1) IL299700B1 (enExample)
MX (1) MX2023000360A (enExample)
WO (1) WO2022010880A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3139063A1 (en) * 2019-05-03 2020-11-12 Praxis Precision Medicines, Inc. Kcnt1 inhibitors and methods of use
WO2020227097A1 (en) * 2019-05-03 2020-11-12 Praxis Precision Medicines, Inc. Kcnt1 inhibitors and methods of use
CA3169779A1 (en) 2020-02-28 2021-09-02 Andrew Mark Griffin Kcnt1 inhibitors and methods of use
US11773088B2 (en) 2020-11-02 2023-10-03 Praxis Precision Medicines, Inc. KCNT1 inhibitors and methods of use
KR20250016137A (ko) * 2022-04-25 2025-02-03 프락시스 프리시젼 메디신즈, 인크. 피라졸 코어를 포함하는 kcnt1 억제제 및 사용 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0127547D0 (en) * 2001-11-16 2002-01-09 Astrazeneca Ab Chemical compounds
WO2005007625A2 (en) * 2003-07-14 2005-01-27 The University Of Tennessee Research Foundation Heterocyclic amides with anti-tuberculosis activity
US20080269241A1 (en) * 2007-02-15 2008-10-30 Darin Allen Bicyclic aminopropyl tetrahydro-pyrazolo-pyridine modulators of cathepsin s
HRP20151052T1 (xx) * 2007-07-19 2015-11-06 H. Lundbeck A/S Peteroäślani heterocikliäśki amidi i srodne tvari
WO2019018119A1 (en) * 2017-07-18 2019-01-24 Pairnomix, Llc METHODS FOR TREATING EPILEPSY AND DISORDERS ASSOCIATED WITH KCNTI
WO2020216919A1 (en) * 2019-04-26 2020-10-29 H. Lundbeck A/S ARYLSULFONYLTHIOPHENECARBOXAMIDES AND ARYLSULFONYLFURANCARBOXAMIDES AS Kν3 POTASSIUM CHANNEL ACTIVATORS
WO2020227097A1 (en) * 2019-05-03 2020-11-12 Praxis Precision Medicines, Inc. Kcnt1 inhibitors and methods of use

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