JP2023532985A5 - - Google Patents
Info
- Publication number
- JP2023532985A5 JP2023532985A5 JP2023500279A JP2023500279A JP2023532985A5 JP 2023532985 A5 JP2023532985 A5 JP 2023532985A5 JP 2023500279 A JP2023500279 A JP 2023500279A JP 2023500279 A JP2023500279 A JP 2023500279A JP 2023532985 A5 JP2023532985 A5 JP 2023532985A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- alkoxy
- cycloalkyl
- epilepsy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063048335P | 2020-07-06 | 2020-07-06 | |
| US63/048,335 | 2020-07-06 | ||
| PCT/US2021/040486 WO2022010880A1 (en) | 2020-07-06 | 2021-07-06 | Kcnt1 inhibitors and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023532985A JP2023532985A (ja) | 2023-08-01 |
| JP2023532985A5 true JP2023532985A5 (enExample) | 2024-07-11 |
| JP7824664B2 JP7824664B2 (ja) | 2026-03-05 |
Family
ID=79552679
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023500279A Active JP7824664B2 (ja) | 2020-07-06 | 2021-07-06 | Kcnt1阻害剤及び使用方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230219921A1 (enExample) |
| EP (1) | EP4175624A4 (enExample) |
| JP (1) | JP7824664B2 (enExample) |
| KR (1) | KR20230035608A (enExample) |
| CN (1) | CN116075297A (enExample) |
| AU (1) | AU2021305058A1 (enExample) |
| CA (1) | CA3188825A1 (enExample) |
| IL (1) | IL299700B1 (enExample) |
| MX (1) | MX2023000360A (enExample) |
| WO (1) | WO2022010880A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3139063A1 (en) * | 2019-05-03 | 2020-11-12 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors and methods of use |
| WO2020227097A1 (en) * | 2019-05-03 | 2020-11-12 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors and methods of use |
| CA3169779A1 (en) | 2020-02-28 | 2021-09-02 | Andrew Mark Griffin | Kcnt1 inhibitors and methods of use |
| US11773088B2 (en) | 2020-11-02 | 2023-10-03 | Praxis Precision Medicines, Inc. | KCNT1 inhibitors and methods of use |
| KR20250016137A (ko) * | 2022-04-25 | 2025-02-03 | 프락시스 프리시젼 메디신즈, 인크. | 피라졸 코어를 포함하는 kcnt1 억제제 및 사용 방법 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0127547D0 (en) * | 2001-11-16 | 2002-01-09 | Astrazeneca Ab | Chemical compounds |
| WO2005007625A2 (en) * | 2003-07-14 | 2005-01-27 | The University Of Tennessee Research Foundation | Heterocyclic amides with anti-tuberculosis activity |
| US20080269241A1 (en) * | 2007-02-15 | 2008-10-30 | Darin Allen | Bicyclic aminopropyl tetrahydro-pyrazolo-pyridine modulators of cathepsin s |
| HRP20151052T1 (xx) * | 2007-07-19 | 2015-11-06 | H. Lundbeck A/S | Peteroäślani heterocikliäśki amidi i srodne tvari |
| WO2019018119A1 (en) * | 2017-07-18 | 2019-01-24 | Pairnomix, Llc | METHODS FOR TREATING EPILEPSY AND DISORDERS ASSOCIATED WITH KCNTI |
| WO2020216919A1 (en) * | 2019-04-26 | 2020-10-29 | H. Lundbeck A/S | ARYLSULFONYLTHIOPHENECARBOXAMIDES AND ARYLSULFONYLFURANCARBOXAMIDES AS Kν3 POTASSIUM CHANNEL ACTIVATORS |
| WO2020227097A1 (en) * | 2019-05-03 | 2020-11-12 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors and methods of use |
-
2021
- 2021-07-06 KR KR1020237004094A patent/KR20230035608A/ko active Pending
- 2021-07-06 MX MX2023000360A patent/MX2023000360A/es unknown
- 2021-07-06 IL IL299700A patent/IL299700B1/en unknown
- 2021-07-06 JP JP2023500279A patent/JP7824664B2/ja active Active
- 2021-07-06 EP EP21838577.1A patent/EP4175624A4/en active Pending
- 2021-07-06 CA CA3188825A patent/CA3188825A1/en active Pending
- 2021-07-06 WO PCT/US2021/040486 patent/WO2022010880A1/en not_active Ceased
- 2021-07-06 CN CN202180053935.4A patent/CN116075297A/zh active Pending
- 2021-07-06 US US18/004,417 patent/US20230219921A1/en active Pending
- 2021-07-06 AU AU2021305058A patent/AU2021305058A1/en active Pending
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