JP2023532021A5 - - Google Patents
Info
- Publication number
- JP2023532021A5 JP2023532021A5 JP2022580142A JP2022580142A JP2023532021A5 JP 2023532021 A5 JP2023532021 A5 JP 2023532021A5 JP 2022580142 A JP2022580142 A JP 2022580142A JP 2022580142 A JP2022580142 A JP 2022580142A JP 2023532021 A5 JP2023532021 A5 JP 2023532021A5
- Authority
- JP
- Japan
- Prior art keywords
- substitution
- wild
- residue
- type human
- human neu2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063047989P | 2020-07-03 | 2020-07-03 | |
| US63/047,989 | 2020-07-03 | ||
| US202163134411P | 2021-01-06 | 2021-01-06 | |
| US63/134,411 | 2021-01-06 | ||
| PCT/US2021/040240 WO2022006492A2 (en) | 2020-07-03 | 2021-07-02 | Recombinant sialidases with reduced protease sensitivity, sialidase fusion proteins, and methods of using the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023532021A JP2023532021A (ja) | 2023-07-26 |
| JP2023532021A5 true JP2023532021A5 (https=) | 2024-07-09 |
Family
ID=79317685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022580142A Pending JP2023532021A (ja) | 2020-07-03 | 2021-07-02 | プロテアーゼ感受性が低減された組換えシアリダーゼ、シアリダーゼ融合タンパク質、及びその使用方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230265406A1 (https=) |
| EP (1) | EP4176056A4 (https=) |
| JP (1) | JP2023532021A (https=) |
| KR (1) | KR20230034320A (https=) |
| CN (1) | CN115803047A (https=) |
| AU (1) | AU2021299565A1 (https=) |
| BR (1) | BR112022026720A2 (https=) |
| CA (1) | CA3173145A1 (https=) |
| IL (1) | IL299559A (https=) |
| MX (1) | MX2023000243A (https=) |
| WO (1) | WO2022006492A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3735458A4 (en) | 2018-01-03 | 2022-04-27 | Palleon Pharmaceuticals Inc. | RECOMBINANT HUMAN SIALIDASES, SIALIDASE FUSION PROTEINS AND METHODS OF USE THEREOF |
| AU2022206263A1 (en) * | 2021-01-06 | 2023-07-20 | Palleon Pharmaceuticals Inc. | Sialidase-her2-antibody fusion proteins and methods of use thereof |
| JP2026509243A (ja) * | 2023-03-10 | 2026-03-17 | ジェネンテック， インコーポレイテッド | プロテアーゼとの融合およびその使用 |
| WO2025217138A1 (en) * | 2024-04-09 | 2025-10-16 | Palleon Pharmaceuticals Inc. | Recombinant human sialidases, sialidase fusion proteins, and methods of using the same |
| WO2026037175A1 (zh) | 2024-08-16 | 2026-02-19 | 上海宝济药业股份有限公司 | 靶向靶细胞的复合物及其应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2014141617A (ru) * | 2012-03-16 | 2016-05-10 | Дженентек, Инк. | Сконструированные конформационно-стабилизированные белки |
| US10138268B2 (en) * | 2014-10-10 | 2018-11-27 | Enzypep B.V. | Peptide fragment condensation and cyclisation using a subtilisin variant with improved synthesis over hydrolysis ratio |
| EP3463447A4 (en) * | 2016-06-03 | 2020-05-27 | Icahn School of Medicine at Mount Sinai | INFLUENZA VIRUS PROTECTION Vaccines |
| EP3735458A4 (en) * | 2018-01-03 | 2022-04-27 | Palleon Pharmaceuticals Inc. | RECOMBINANT HUMAN SIALIDASES, SIALIDASE FUSION PROTEINS AND METHODS OF USE THEREOF |
| AU2022206263A1 (en) * | 2021-01-06 | 2023-07-20 | Palleon Pharmaceuticals Inc. | Sialidase-her2-antibody fusion proteins and methods of use thereof |
| CN116829188A (zh) * | 2021-01-06 | 2023-09-29 | 帕利昂制药有限公司 | 抗pd-l1抗体及其融合蛋白 |
-
2021
- 2021-07-02 CA CA3173145A patent/CA3173145A1/en active Pending
- 2021-07-02 US US18/003,234 patent/US20230265406A1/en active Pending
- 2021-07-02 WO PCT/US2021/040240 patent/WO2022006492A2/en not_active Ceased
- 2021-07-02 JP JP2022580142A patent/JP2023532021A/ja active Pending
- 2021-07-02 BR BR112022026720A patent/BR112022026720A2/pt unknown
- 2021-07-02 MX MX2023000243A patent/MX2023000243A/es unknown
- 2021-07-02 CN CN202180047881.0A patent/CN115803047A/zh active Pending
- 2021-07-02 KR KR1020237003002A patent/KR20230034320A/ko active Pending
- 2021-07-02 AU AU2021299565A patent/AU2021299565A1/en active Pending
- 2021-07-02 IL IL299559A patent/IL299559A/en unknown
- 2021-07-02 EP EP21833741.8A patent/EP4176056A4/en active Pending
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