JP2023530936A - 真菌感染症を処置するための化合物および方法 - Google Patents

真菌感染症を処置するための化合物および方法 Download PDF

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Publication number
JP2023530936A
JP2023530936A JP2022577084A JP2022577084A JP2023530936A JP 2023530936 A JP2023530936 A JP 2023530936A JP 2022577084 A JP2022577084 A JP 2022577084A JP 2022577084 A JP2022577084 A JP 2022577084A JP 2023530936 A JP2023530936 A JP 2023530936A
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JP
Japan
Prior art keywords
compound
spp
acceptable salt
pharmaceutically acceptable
solvate
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JP2022577084A
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English (en)
Japanese (ja)
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JP2023530936A5 (https=
Inventor
ジョイ ショー カレン
シュラム ハラン
アール．ホッジス マイケル
Original Assignee
アンプリックス ファーマシューティカルズ，インク．
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Publication of JP2023530936A publication Critical patent/JP2023530936A/ja
Publication of JP2023530936A5 publication Critical patent/JP2023530936A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2022577084A 2020-06-17 2021-06-16 真菌感染症を処置するための化合物および方法 Pending JP2023530936A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063040450P 2020-06-17 2020-06-17
US63/040,450 2020-06-17
PCT/US2021/037578 WO2021257670A1 (en) 2020-06-17 2021-06-16 Compounds and methods for treating fungal infections

Publications (2)

Publication Number Publication Date
JP2023530936A true JP2023530936A (ja) 2023-07-20
JP2023530936A5 JP2023530936A5 (https=) 2024-06-21

Family

ID=79268375

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022577084A Pending JP2023530936A (ja) 2020-06-17 2021-06-16 真菌感染症を処置するための化合物および方法

Country Status (12)

Country Link
US (1) US20230233586A1 (https=)
EP (1) EP4167998A4 (https=)
JP (1) JP2023530936A (https=)
KR (1) KR20230024375A (https=)
CN (1) CN115884775A (https=)
AU (1) AU2021293911B2 (https=)
BR (1) BR112022024988A2 (https=)
CA (1) CA3187268A1 (https=)
IL (1) IL299057A (https=)
MX (1) MX2022016179A (https=)
TW (1) TWI888580B (https=)
WO (1) WO2021257670A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2022010804A (es) 2020-03-04 2023-01-16 Amplyx Pharmaceuticals Inc Uso de compuestos en el tratamiento de infecciones fungicas.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020047510A1 (en) * 2018-08-31 2020-03-05 Amplyx Pharmaceuticals, Inc. Compounds and methods for treating fungal infections
JP2023516648A (ja) * 2020-03-04 2023-04-20 アンプリックス ファーマシューティカルズ，インク． 真菌感染症の処置における化合物の使用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI385169B (zh) * 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd 經雜環取代之吡啶衍生物及含有彼之抗真菌劑
US8513287B2 (en) * 2007-12-27 2013-08-20 Eisai R&D Management Co., Ltd. Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same
EP2636409A1 (en) * 2010-11-05 2013-09-11 Eisai R&D Management Co., Ltd. Combined pharmaceutical composition as antifungal agent
US11819503B2 (en) * 2019-04-23 2023-11-21 F2G Ltd Method of treating coccidioides infection

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020047510A1 (en) * 2018-08-31 2020-03-05 Amplyx Pharmaceuticals, Inc. Compounds and methods for treating fungal infections
JP2023516648A (ja) * 2020-03-04 2023-04-20 アンプリックス ファーマシューティカルズ，インク． 真菌感染症の処置における化合物の使用

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J POSTGRAD MED, vol. Vol.51, Suppl.1, JPN6025023813, 2005, pages 30 - 36, ISSN: 0005759941 *

Also Published As

Publication number Publication date
CA3187268A1 (en) 2021-12-23
EP4167998A1 (en) 2023-04-26
AU2021293911A1 (en) 2023-01-19
AU2021293911B2 (en) 2024-11-14
US20230233586A1 (en) 2023-07-27
KR20230024375A (ko) 2023-02-20
BR112022024988A2 (pt) 2022-12-27
WO2021257670A1 (en) 2021-12-23
MX2022016179A (es) 2023-04-20
EP4167998A4 (en) 2024-07-17
CN115884775A (zh) 2023-03-31
TW202214258A (zh) 2022-04-16
TWI888580B (zh) 2025-07-01
IL299057A (en) 2023-02-01

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