KR20230024375A - 진균 감염을 치료하기 위한 화합물 및 방법 - Google Patents

진균 감염을 치료하기 위한 화합물 및 방법 Download PDF

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Publication number
KR20230024375A
KR20230024375A KR1020237001328A KR20237001328A KR20230024375A KR 20230024375 A KR20230024375 A KR 20230024375A KR 1020237001328 A KR1020237001328 A KR 1020237001328A KR 20237001328 A KR20237001328 A KR 20237001328A KR 20230024375 A KR20230024375 A KR 20230024375A
Authority
KR
South Korea
Prior art keywords
compound
pharmaceutically acceptable
solvate
hydrate
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020237001328A
Other languages
English (en)
Korean (ko)
Inventor
캐런 조이 쇼
하란 쉬람
마이클 알. 호지스
Original Assignee
앰플릭스 파마슈티컬스, 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 앰플릭스 파마슈티컬스, 인크. filed Critical 앰플릭스 파마슈티컬스, 인크.
Publication of KR20230024375A publication Critical patent/KR20230024375A/ko
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020237001328A 2020-06-17 2021-06-16 진균 감염을 치료하기 위한 화합물 및 방법 Ceased KR20230024375A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063040450P 2020-06-17 2020-06-17
US63/040,450 2020-06-17
PCT/US2021/037578 WO2021257670A1 (en) 2020-06-17 2021-06-16 Compounds and methods for treating fungal infections

Publications (1)

Publication Number Publication Date
KR20230024375A true KR20230024375A (ko) 2023-02-20

Family

ID=79268375

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237001328A Ceased KR20230024375A (ko) 2020-06-17 2021-06-16 진균 감염을 치료하기 위한 화합물 및 방법

Country Status (12)

Country Link
US (1) US20230233586A1 (https=)
EP (1) EP4167998A4 (https=)
JP (1) JP2023530936A (https=)
KR (1) KR20230024375A (https=)
CN (1) CN115884775A (https=)
AU (1) AU2021293911B2 (https=)
BR (1) BR112022024988A2 (https=)
CA (1) CA3187268A1 (https=)
IL (1) IL299057A (https=)
MX (1) MX2022016179A (https=)
TW (1) TWI888580B (https=)
WO (1) WO2021257670A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2022010804A (es) 2020-03-04 2023-01-16 Amplyx Pharmaceuticals Inc Uso de compuestos en el tratamiento de infecciones fungicas.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI385169B (zh) * 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd 經雜環取代之吡啶衍生物及含有彼之抗真菌劑
US8513287B2 (en) * 2007-12-27 2013-08-20 Eisai R&D Management Co., Ltd. Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same
EP2636409A1 (en) * 2010-11-05 2013-09-11 Eisai R&D Management Co., Ltd. Combined pharmaceutical composition as antifungal agent
WO2020047510A1 (en) * 2018-08-31 2020-03-05 Amplyx Pharmaceuticals, Inc. Compounds and methods for treating fungal infections
US11819503B2 (en) * 2019-04-23 2023-11-21 F2G Ltd Method of treating coccidioides infection
MX2022010804A (es) * 2020-03-04 2023-01-16 Amplyx Pharmaceuticals Inc Uso de compuestos en el tratamiento de infecciones fungicas.

Also Published As

Publication number Publication date
CA3187268A1 (en) 2021-12-23
EP4167998A1 (en) 2023-04-26
JP2023530936A (ja) 2023-07-20
AU2021293911A1 (en) 2023-01-19
AU2021293911B2 (en) 2024-11-14
US20230233586A1 (en) 2023-07-27
BR112022024988A2 (pt) 2022-12-27
WO2021257670A1 (en) 2021-12-23
MX2022016179A (es) 2023-04-20
EP4167998A4 (en) 2024-07-17
CN115884775A (zh) 2023-03-31
TW202214258A (zh) 2022-04-16
TWI888580B (zh) 2025-07-01
IL299057A (en) 2023-02-01

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