JP2023526234A5 - - Google Patents
Info
- Publication number
- JP2023526234A5 JP2023526234A5 JP2022568746A JP2022568746A JP2023526234A5 JP 2023526234 A5 JP2023526234 A5 JP 2023526234A5 JP 2022568746 A JP2022568746 A JP 2022568746A JP 2022568746 A JP2022568746 A JP 2022568746A JP 2023526234 A5 JP2023526234 A5 JP 2023526234A5
- Authority
- JP
- Japan
- Prior art keywords
- approximately
- spacer
- acid sequence
- amino acid
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063023751P | 2020-05-12 | 2020-05-12 | |
| US63/023,751 | 2020-05-12 | ||
| PCT/US2021/032098 WO2021231655A1 (en) | 2020-05-12 | 2021-05-12 | Chimeric antigen receptor spacers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023526234A JP2023526234A (ja) | 2023-06-21 |
| JP2023526234A5 true JP2023526234A5 (https=) | 2024-07-31 |
Family
ID=76250478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022568746A Pending JP2023526234A (ja) | 2020-05-12 | 2021-05-12 | キメラ抗原受容体スペーサー |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20210380658A1 (https=) |
| EP (1) | EP4149968A1 (https=) |
| JP (1) | JP2023526234A (https=) |
| KR (1) | KR20230022411A (https=) |
| CN (1) | CN116096739A (https=) |
| AU (1) | AU2021270299A1 (https=) |
| BR (1) | BR112022022953A2 (https=) |
| CA (1) | CA3157427A1 (https=) |
| IL (1) | IL298114A (https=) |
| MX (1) | MX2022014203A (https=) |
| WO (1) | WO2021231655A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021189008A1 (en) | 2020-03-20 | 2021-09-23 | Lyell Immunopharma, Inc. | Novel recombinant cell surface markers |
| US12144827B2 (en) | 2021-02-25 | 2024-11-19 | Lyell Immunopharma, Inc. | ROR1 targeting chimeric antigen receptor |
| EP4430068A4 (en) * | 2021-11-10 | 2025-11-19 | Outpace Bio Inc | CHIMER ANTIGEN RECEPTORS |
| CN115724986B (zh) * | 2022-07-11 | 2024-07-19 | 惠和生物技术(上海)有限公司 | 三特异性抗体及其用途 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| EP1958962A3 (en) | 1997-06-12 | 2013-05-01 | Novartis International Pharmaceutical Ltd. | Artificial antibody polypeptides |
| CN1294148C (zh) | 2001-04-11 | 2007-01-10 | 中国科学院遗传与发育生物学研究所 | 环状单链三特异抗体 |
| KR20060041205A (ko) | 2003-07-01 | 2006-05-11 | 이뮤노메딕스, 인코오포레이티드 | 양특이성 항체들의 다가 담체들 |
| EP1786918A4 (en) | 2004-07-17 | 2009-02-11 | Imclone Systems Inc | NEW BISPECIFIC ANTIBODY TETRAVALENT |
| NZ612578A (en) | 2005-08-19 | 2014-11-28 | Abbvie Inc | Dual variable domain immunoglobin and uses thereof |
| US20100047171A1 (en) * | 2006-01-24 | 2010-02-25 | Roland Beckmann | Fusion Proteins That Contain Natural Junctions |
| CA2759733C (en) | 2009-04-23 | 2019-09-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-human ror1 antibodies |
| ES2657970T3 (es) | 2010-12-01 | 2018-03-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anticuerpos contra ROR1 de conejo/ser humano quiméricos |
| GB201203071D0 (en) * | 2012-02-22 | 2012-04-04 | Ucb Pharma Sa | Biological products |
| BR122020002986A8 (pt) * | 2012-08-20 | 2023-04-18 | Seattle Childrens Hospital Dba Seattle Childrens Res Inst | Método e composições para imunoterapia celular |
| CN113307880B (zh) * | 2014-01-13 | 2025-07-04 | 希望之城公司 | 在Fc间隔物区中具有突变的嵌合抗原受体(CAR)及其使用方法 |
| WO2016016344A1 (en) * | 2014-07-29 | 2016-02-04 | Cellectis | Ror1(ntrkr1)specific chimeric antigen receptors for cancer immunotherapy |
| ES2818103T3 (es) * | 2015-01-16 | 2021-04-09 | Juno Therapeutics Inc | Anticuerpos y receptores de antígenos quiméricos específicos para ROR1 |
| GB201803079D0 (en) * | 2018-02-26 | 2018-04-11 | Autolus Ltd | Cell |
| EP3765041A4 (en) * | 2018-03-14 | 2021-12-22 | Seattle Children's Hospital (DBA Seattle Children's Research Institute) | IL-13 CHIMERIC RECEPTOR ALPHA 2 (IL13RA2) ANTIGEN RECEPTOR FOR T-CELL T-CELL IMMUNOTHERAPY |
| EP3774866A1 (en) * | 2018-04-13 | 2021-02-17 | Ludwig Institute for Cancer Research Ltd | Heterodimeric inactivatable chimeric antigen receptors |
| KR20210044736A (ko) * | 2018-05-03 | 2021-04-23 | 주노 쎄러퓨티크스 인코퍼레이티드 | 키메라 항원 수용체(car) t세포 요법과 키나제 억제제의 조합요법 |
| WO2019241557A1 (en) * | 2018-06-15 | 2019-12-19 | The Regents Of The University Of California | Fusion fragment chimeric antigen receptors and uses thereof |
| US20220144916A1 (en) * | 2019-02-12 | 2022-05-12 | Board Of Regents, The University Of Texas System | High affinity engineered t-cell receptors targeting cmv infected cells |
| WO2020254591A1 (en) * | 2019-06-19 | 2020-12-24 | Julius-Maximilians-Universität Würzburg | Ultramodular igg3-based spacer domain and multi-function site for implementation in chimeric antigen receptor design |
-
2021
- 2021-05-12 BR BR112022022953A patent/BR112022022953A2/pt unknown
- 2021-05-12 CN CN202180048789.6A patent/CN116096739A/zh active Pending
- 2021-05-12 IL IL298114A patent/IL298114A/en unknown
- 2021-05-12 MX MX2022014203A patent/MX2022014203A/es unknown
- 2021-05-12 US US17/318,996 patent/US20210380658A1/en not_active Abandoned
- 2021-05-12 KR KR1020227043445A patent/KR20230022411A/ko active Pending
- 2021-05-12 JP JP2022568746A patent/JP2023526234A/ja active Pending
- 2021-05-12 EP EP21729739.9A patent/EP4149968A1/en active Pending
- 2021-05-12 AU AU2021270299A patent/AU2021270299A1/en active Pending
- 2021-05-12 CA CA3157427A patent/CA3157427A1/en active Pending
- 2021-05-12 WO PCT/US2021/032098 patent/WO2021231655A1/en not_active Ceased
-
2025
- 2025-09-08 US US19/322,325 patent/US20260098075A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023526234A5 (https=) | ||
| US11180553B2 (en) | Chimeric antigen receptor | |
| JP7579795B2 (ja) | NKp30に結合する抗体分子およびその使用 | |
| CN112771167B (zh) | 表达有趋化因子的细胞及用途 | |
| CN110616191B (zh) | 共刺激配体联合的car t疗法 | |
| US11332513B2 (en) | Chimeric antigen receptors having GITR intracellular domain as co-stimulatory domain | |
| KR20180057720A (ko) | 다가 Fv 항체 | |
| IL294518A (en) | Bcma-directed cellular immunotherapy compositions and methods | |
| TW201841944A (zh) | 4-1bbl變異體及包含其之融合蛋白 | |
| JP2024525727A5 (https=) | ||
| US20220133792A1 (en) | Signaling platforms for chimeric antigen receptor t cells | |
| JP2024510900A5 (https=) | ||
| CN110423757B (zh) | 一种工程化核酸、t细胞及其应用和产生方法 | |
| JP2025536940A (ja) | 新規cd19バインダー、それを含むcar-t構造体、およびその使用方法 | |
| WO2021057906A1 (zh) | 表达il-15的免疫效应细胞 | |
| WO2022057941A1 (zh) | 表达il-7r结合蛋白的免疫效应细胞 | |
| EP3749688A1 (en) | Chimeric receptor | |
| JP2025535365A (ja) | Il18と結合した新規cd19結合体を含むcar-t構築物およびその使用方法 | |
| WO2023051361A1 (zh) | 工程化免疫细胞及其用途 | |
| CN115073606A (zh) | 一种靶向表达cldn 18.2的细胞的人源化嵌合抗原受体 | |
| WO2020162452A1 (ja) | CARライブラリおよびscFvの製造方法 | |
| CN110540997A (zh) | 靶向bcma嵌合抗原受体、核酸序列、载体及应用 | |
| CN120322459A (zh) | 多特异性蛋白及相关方法 | |
| JP2025506515A5 (https=) | ||
| WO2023035947A1 (zh) | 工程化免疫细胞及其用途 |