JP2023525263A5 - - Google Patents

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Publication number
JP2023525263A5
JP2023525263A5 JP2022567585A JP2022567585A JP2023525263A5 JP 2023525263 A5 JP2023525263 A5 JP 2023525263A5 JP 2022567585 A JP2022567585 A JP 2022567585A JP 2022567585 A JP2022567585 A JP 2022567585A JP 2023525263 A5 JP2023525263 A5 JP 2023525263A5
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Japan
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sequence
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JP2022567585A
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Japanese (ja)
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JP2023525263A (ja
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Priority claimed from PCT/GB2021/051060 external-priority patent/WO2021224599A1/en
Publication of JP2023525263A publication Critical patent/JP2023525263A/ja
Publication of JP2023525263A5 publication Critical patent/JP2023525263A5/ja
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JP2022567585A 2020-05-05 2021-05-04 Cd163不活化のターゲティングにより、ブタ種の健康状態を改善するための方法 Pending JP2023525263A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063020128P 2020-05-05 2020-05-05
US63/020,128 2020-05-05
US202063021370P 2020-05-07 2020-05-07
US63/021,370 2020-05-07
PCT/GB2021/051060 WO2021224599A1 (en) 2020-05-05 2021-05-04 Methods for improving the health of porcine species by targeted inactivation of cd163

Publications (2)

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JP2023525263A JP2023525263A (ja) 2023-06-15
JP2023525263A5 true JP2023525263A5 (https=) 2024-04-25

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JP2022567585A Pending JP2023525263A (ja) 2020-05-05 2021-05-04 Cd163不活化のターゲティングにより、ブタ種の健康状態を改善するための方法

Country Status (10)

Country Link
US (5) US11208659B2 (https=)
EP (1) EP4145991A1 (https=)
JP (1) JP2023525263A (https=)
KR (1) KR20230006827A (https=)
CN (5) CN118773199A (https=)
AU (1) AU2021268263A1 (https=)
BR (1) BR112022020072A2 (https=)
CA (1) CA3179710A1 (https=)
MX (1) MX2022013704A (https=)
WO (1) WO2021224599A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3179710A1 (en) * 2020-05-05 2021-11-11 Andrew Mark CIGAN Methods for improving the health of porcine species by targeted inactivation of cd163
US20250064032A1 (en) 2021-12-10 2025-02-27 Pig Improvement Company Uk Limited Editing tmprss2/4 for disease resistance in livestock
WO2024097603A2 (en) * 2022-11-02 2024-05-10 Abs Global, Inc. Method of creating gene edited animals comprising a wild type allele

Family Cites Families (19)

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Publication number Priority date Publication date Assignee Title
US4873191A (en) 1981-06-12 1989-10-10 Ohio University Genetic transformation of zygotes
PT2709445T (pt) 2011-05-16 2018-11-27 Univ Missouri Animais resistentes ao vírus da síntese reprodutiva e respiratória porcino
AU2013266968B2 (en) 2012-05-25 2017-06-29 Emmanuelle CHARPENTIER Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription
US20140068727A1 (en) 2012-09-05 2014-03-06 Apple Inc. Wi-fi credential sharing using images
GB201313235D0 (en) * 2013-07-24 2013-09-04 Univ Edinburgh Antiviral Compositions Methods and Animals
CN104593422A (zh) * 2015-01-08 2015-05-06 中国农业大学 一种抗蓝耳病克隆猪的制备方法
CA3255239A1 (en) 2015-08-06 2026-03-02 The Curators Of The University Of Missouri Pathogen-resistant animals having modified cd163 genes
RS65691B1 (sr) * 2015-08-06 2024-07-31 Univ Missouri Svinja i ćelije rezistentne na virus reproduktivnog i respiratornog sindroma svinja (prrsv) koje imaju modifikovane cd163 gene
GB201617559D0 (en) * 2016-10-17 2016-11-30 University Court Of The University Of Edinburgh The Swine comprising modified cd163 and associated methods
CN107177595A (zh) * 2017-06-07 2017-09-19 浙江大学 用于猪CD163基因编辑的靶向sgRNA、修饰载体及其制备方法和应用
CN107354170A (zh) * 2017-08-24 2017-11-17 中国农业科学院北京畜牧兽医研究所 一种基因敲除载体以及制备cd163基因敲除猪成纤维细胞的方法
CN108103099B (zh) * 2017-12-18 2022-03-04 中山大学 一种抗蓝耳病Marc-145细胞系及其制备方法和应用
KR102680060B1 (ko) 2018-04-17 2024-07-02 더 큐레이터스 오브 더 유니버시티 오브 미주리 바이러스에 의한 감염으로부터 돼지 태아를 보호하는 방법
CN108823248A (zh) * 2018-04-20 2018-11-16 中山大学 一种利用CRISPR/Cas9编辑陆川猪CD163基因的方法
CN108753832A (zh) * 2018-04-20 2018-11-06 中山大学 一种利用CRISPR/Cas9编辑大白猪CD163基因的方法
CN109055385B (zh) * 2018-08-21 2021-08-27 吉林大学 一种有效抑制ⅱ型prrsv感染的基因序列及其应用
CN109666646A (zh) * 2018-11-15 2019-04-23 广东省农业科学院农业生物基因研究中心 一种cd163基因编辑的猪胚胎成纤维细胞系的制备及应用
CN110951745A (zh) * 2019-10-30 2020-04-03 内蒙古大学 Cd163突变基因及其在抑制或阻断猪产生抗体的方法和应用
CA3179710A1 (en) * 2020-05-05 2021-11-11 Andrew Mark CIGAN Methods for improving the health of porcine species by targeted inactivation of cd163

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