JP2023525263A5 - - Google Patents
Info
- Publication number
- JP2023525263A5 JP2023525263A5 JP2022567585A JP2022567585A JP2023525263A5 JP 2023525263 A5 JP2023525263 A5 JP 2023525263A5 JP 2022567585 A JP2022567585 A JP 2022567585A JP 2022567585 A JP2022567585 A JP 2022567585A JP 2023525263 A5 JP2023525263 A5 JP 2023525263A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nos
- sequence
- ids
- sequence ids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063020128P | 2020-05-05 | 2020-05-05 | |
| US63/020,128 | 2020-05-05 | ||
| US202063021370P | 2020-05-07 | 2020-05-07 | |
| US63/021,370 | 2020-05-07 | ||
| PCT/GB2021/051060 WO2021224599A1 (en) | 2020-05-05 | 2021-05-04 | Methods for improving the health of porcine species by targeted inactivation of cd163 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023525263A JP2023525263A (ja) | 2023-06-15 |
| JP2023525263A5 true JP2023525263A5 (https=) | 2024-04-25 |
Family
ID=75954141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022567585A Pending JP2023525263A (ja) | 2020-05-05 | 2021-05-04 | Cd163不活化のターゲティングにより、ブタ種の健康状態を改善するための方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US11208659B2 (https=) |
| EP (1) | EP4145991A1 (https=) |
| JP (1) | JP2023525263A (https=) |
| KR (1) | KR20230006827A (https=) |
| CN (5) | CN118773199A (https=) |
| AU (1) | AU2021268263A1 (https=) |
| BR (1) | BR112022020072A2 (https=) |
| CA (1) | CA3179710A1 (https=) |
| MX (1) | MX2022013704A (https=) |
| WO (1) | WO2021224599A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3179710A1 (en) * | 2020-05-05 | 2021-11-11 | Andrew Mark CIGAN | Methods for improving the health of porcine species by targeted inactivation of cd163 |
| US20250064032A1 (en) | 2021-12-10 | 2025-02-27 | Pig Improvement Company Uk Limited | Editing tmprss2/4 for disease resistance in livestock |
| WO2024097603A2 (en) * | 2022-11-02 | 2024-05-10 | Abs Global, Inc. | Method of creating gene edited animals comprising a wild type allele |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4873191A (en) | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
| PT2709445T (pt) | 2011-05-16 | 2018-11-27 | Univ Missouri | Animais resistentes ao vírus da síntese reprodutiva e respiratória porcino |
| AU2013266968B2 (en) | 2012-05-25 | 2017-06-29 | Emmanuelle CHARPENTIER | Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription |
| US20140068727A1 (en) | 2012-09-05 | 2014-03-06 | Apple Inc. | Wi-fi credential sharing using images |
| GB201313235D0 (en) * | 2013-07-24 | 2013-09-04 | Univ Edinburgh | Antiviral Compositions Methods and Animals |
| CN104593422A (zh) * | 2015-01-08 | 2015-05-06 | 中国农业大学 | 一种抗蓝耳病克隆猪的制备方法 |
| CA3255239A1 (en) | 2015-08-06 | 2026-03-02 | The Curators Of The University Of Missouri | Pathogen-resistant animals having modified cd163 genes |
| RS65691B1 (sr) * | 2015-08-06 | 2024-07-31 | Univ Missouri | Svinja i ćelije rezistentne na virus reproduktivnog i respiratornog sindroma svinja (prrsv) koje imaju modifikovane cd163 gene |
| GB201617559D0 (en) * | 2016-10-17 | 2016-11-30 | University Court Of The University Of Edinburgh The | Swine comprising modified cd163 and associated methods |
| CN107177595A (zh) * | 2017-06-07 | 2017-09-19 | 浙江大学 | 用于猪CD163基因编辑的靶向sgRNA、修饰载体及其制备方法和应用 |
| CN107354170A (zh) * | 2017-08-24 | 2017-11-17 | 中国农业科学院北京畜牧兽医研究所 | 一种基因敲除载体以及制备cd163基因敲除猪成纤维细胞的方法 |
| CN108103099B (zh) * | 2017-12-18 | 2022-03-04 | 中山大学 | 一种抗蓝耳病Marc-145细胞系及其制备方法和应用 |
| KR102680060B1 (ko) | 2018-04-17 | 2024-07-02 | 더 큐레이터스 오브 더 유니버시티 오브 미주리 | 바이러스에 의한 감염으로부터 돼지 태아를 보호하는 방법 |
| CN108823248A (zh) * | 2018-04-20 | 2018-11-16 | 中山大学 | 一种利用CRISPR/Cas9编辑陆川猪CD163基因的方法 |
| CN108753832A (zh) * | 2018-04-20 | 2018-11-06 | 中山大学 | 一种利用CRISPR/Cas9编辑大白猪CD163基因的方法 |
| CN109055385B (zh) * | 2018-08-21 | 2021-08-27 | 吉林大学 | 一种有效抑制ⅱ型prrsv感染的基因序列及其应用 |
| CN109666646A (zh) * | 2018-11-15 | 2019-04-23 | 广东省农业科学院农业生物基因研究中心 | 一种cd163基因编辑的猪胚胎成纤维细胞系的制备及应用 |
| CN110951745A (zh) * | 2019-10-30 | 2020-04-03 | 内蒙古大学 | Cd163突变基因及其在抑制或阻断猪产生抗体的方法和应用 |
| CA3179710A1 (en) * | 2020-05-05 | 2021-11-11 | Andrew Mark CIGAN | Methods for improving the health of porcine species by targeted inactivation of cd163 |
-
2021
- 2021-05-04 CA CA3179710A patent/CA3179710A1/en active Pending
- 2021-05-04 WO PCT/GB2021/051060 patent/WO2021224599A1/en not_active Ceased
- 2021-05-04 MX MX2022013704A patent/MX2022013704A/es unknown
- 2021-05-04 BR BR112022020072A patent/BR112022020072A2/pt unknown
- 2021-05-04 US US17/307,369 patent/US11208659B2/en active Active
- 2021-05-04 KR KR1020227038847A patent/KR20230006827A/ko active Pending
- 2021-05-04 EP EP21726165.0A patent/EP4145991A1/en active Pending
- 2021-05-04 JP JP2022567585A patent/JP2023525263A/ja active Pending
- 2021-05-04 AU AU2021268263A patent/AU2021268263A1/en active Pending
- 2021-05-06 CN CN202410894567.1A patent/CN118773199A/zh active Pending
- 2021-05-06 CN CN202410894582.6A patent/CN118879712A/zh active Pending
- 2021-05-06 CN CN202410894572.2A patent/CN118620905A/zh active Pending
- 2021-05-06 CN CN202110489495.9A patent/CN113151291B/zh active Active
- 2021-05-06 CN CN202311146361.2A patent/CN117487855B/zh active Active
- 2021-10-29 US US17/515,139 patent/US12416005B2/en active Active
-
2022
- 2022-01-21 US US17/581,239 patent/US11535850B2/en active Active
-
2023
- 2023-03-29 US US18/192,492 patent/US12371692B2/en active Active
-
2025
- 2025-08-15 US US19/301,583 patent/US20260092277A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Niu et al. | Efficient generation of goats with defined point mutation (I397V) in GDF9 through CRISPR/Cas9 | |
| CN110551759B (zh) | 一种提高转基因细胞重组效率的组合物及方法 | |
| EP3392337A1 (en) | Genetic modification non-human organism, egg cells, fertilized eggs, and method for modifying target genes | |
| JP2023525263A5 (https=) | ||
| JP6958917B2 (ja) | 遺伝子ノックイン細胞の作製方法 | |
| CN106282231B (zh) | 粘多糖贮积症ii型动物模型的构建方法及应用 | |
| CN105925579B (zh) | 一对特异性识别猪IGF2基因内含子的sgRNA及其编码DNA与应用 | |
| WO2020077930A1 (zh) | 一种应用Cas9技术制备CKO/KI动物模型的方法 | |
| CN117859703B (zh) | Anxa11基因的新突变致病位点C104G的敲入小鼠模型及其构建方法与应用 | |
| CN105950625A (zh) | 一对特异性识别猪MSTN基因启动子的sgRNA及其编码DNA与应用 | |
| CN109280666A (zh) | 一种基因敲除选育bai2基因缺失型斑马鱼的方法 | |
| CN120041455A (zh) | 构建TBX19 p.Thr187Ala点突变小鼠模型的试剂盒及其构建方法和应用 | |
| CN114075566B (zh) | 水牛asip基因插入突变及其分子鉴定方法和应用 | |
| CN117535347A (zh) | 一种斑马鱼gnai2a基因突变体模型建立方法 | |
| CN108531616A (zh) | 一种牦牛体格相关的基因分子标记、检测方法和试剂盒 | |
| Polasik et al. | Analysis of the myostatin gene (MSTN) polymorphism in four breeds of horses | |
| CN105647885B (zh) | Cas9融合蛋白及其编码序列 | |
| CN109468324A (zh) | 一种基因敲除选育pdlim5b基因缺失型斑马鱼的方法 | |
| Li et al. | A CR1 element is embedded in a novel tandem repeat (Hin fI repeat) within the chicken genome | |
| de León et al. | Genómica y producción animal | |
| WO2017055844A1 (en) | Genetically-edited swine | |
| CN111979272A (zh) | 制备视网膜病变的非人哺乳动物模型的方法及其应用 | |
| Buslyk et al. | Sequence analysis of the 3′ UTR region of the myostatin gene in Ukrainian Carpathian Mountain sheep | |
| Pan et al. | Sequencing, tissue distribution and physical mapping of the porcine homologue of cardiomyopathy associated 3 (CMYA3). | |
| CN117660527B (zh) | 一种ABCA7-Floxp小鼠模型的构建方法和应用 |