JP2023524692A5 - - Google Patents
Info
- Publication number
- JP2023524692A5 JP2023524692A5 JP2022566135A JP2022566135A JP2023524692A5 JP 2023524692 A5 JP2023524692 A5 JP 2023524692A5 JP 2022566135 A JP2022566135 A JP 2022566135A JP 2022566135 A JP2022566135 A JP 2022566135A JP 2023524692 A5 JP2023524692 A5 JP 2023524692A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- process according
- solvent
- reaction mixture
- item
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025104881A JP2025128388A (ja) | 2020-04-30 | 2025-06-20 | キナーゼ阻害剤を調製するためのプロセス |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063017739P | 2020-04-30 | 2020-04-30 | |
| US63/017,739 | 2020-04-30 | ||
| PCT/US2021/030035 WO2021222673A1 (en) | 2020-04-30 | 2021-04-30 | Processes for the preparation of a kinase inhibitor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025104881A Division JP2025128388A (ja) | 2020-04-30 | 2025-06-20 | キナーゼ阻害剤を調製するためのプロセス |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023524692A JP2023524692A (ja) | 2023-06-13 |
| JP2023524692A5 true JP2023524692A5 (https=) | 2024-04-30 |
| JP7728795B2 JP7728795B2 (ja) | 2025-08-25 |
Family
ID=76076455
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022566135A Active JP7728795B2 (ja) | 2020-04-30 | 2021-04-30 | キナーゼ阻害剤を調製するためのプロセス |
| JP2025104881A Pending JP2025128388A (ja) | 2020-04-30 | 2025-06-20 | キナーゼ阻害剤を調製するためのプロセス |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025104881A Pending JP2025128388A (ja) | 2020-04-30 | 2025-06-20 | キナーゼ阻害剤を調製するためのプロセス |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US12497367B2 (https=) |
| EP (1) | EP4143169B1 (https=) |
| JP (2) | JP7728795B2 (https=) |
| KR (1) | KR20230005190A (https=) |
| CN (2) | CN115461328B (https=) |
| AU (1) | AU2021263474A1 (https=) |
| BR (1) | BR112022021712A2 (https=) |
| CA (1) | CA3176042A1 (https=) |
| CL (1) | CL2022003008A1 (https=) |
| CO (1) | CO2022015205A2 (https=) |
| CR (1) | CR20220551A (https=) |
| GE (1) | GEP20267875B (https=) |
| IL (2) | IL297684B1 (https=) |
| MX (1) | MX2022013528A (https=) |
| PE (1) | PE20230110A1 (https=) |
| PH (1) | PH12022552821A1 (https=) |
| TW (1) | TWI887405B (https=) |
| WO (1) | WO2021222673A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117402114A (zh) * | 2018-01-26 | 2024-01-16 | 埃克塞里艾克西斯公司 | 用于治疗激酶依赖性病症的化合物 |
| TW202334090A (zh) * | 2021-11-03 | 2023-09-01 | 美商艾克塞里克斯公司 | 用於治療激酶依賴性病症之化合物 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1154105A (zh) * | 1994-06-08 | 1997-07-09 | H·隆德贝克有限公司 | 4-芳基-1-(二氢化茚甲基、二氢苯并呋喃甲基或二氢苯并噻吩甲基)哌啶、-四氢吡啶或哌嗪类化合物 |
| ZA954689B (en) | 1994-06-08 | 1996-01-29 | Lundbeck & Co As H | 4-Aryl-1-(indanmethyl dihydrobenzofuranmethyl or dihydrobenzothiophenemethyl) piperidines tetrahydropyridines or piperazines |
| CN101466672B (zh) * | 2006-06-12 | 2012-05-16 | 诺瓦提斯公司 | N-羟基-3-[4-[[[2-(2-甲基-1h-吲哚-3-基)乙基]氨基]甲基]苯基]-2e-2-丙烯酰胺的盐 |
| NZ572547A (en) | 2006-06-12 | 2011-06-30 | Novartis Ag | SALTS OF N-HYDROXY-3-[4-[[[2-(2-METHYL-1H-INDOL-3-yl)ETHYL]AMINO]METHYL]PHENYL]-2E-2-PROPENAMIDE |
| JP5486606B2 (ja) * | 2008-11-13 | 2014-05-07 | エクセリクシス， インク． | キノリン誘導体の調製方法 |
| NZ779754A (en) * | 2009-01-16 | 2023-04-28 | Exelixis Inc | Malate salt of n-(4-{ [6,7-bis(methyloxy)quinolin-4-yl] oxy} phenyl)-n’-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, and crystalline forms thereof for the treatment of cancer |
| EA030435B1 (ru) | 2010-07-16 | 2018-08-31 | Экселиксис, Инк. | ТАБЛЕТКА, СОДЕРЖАЩАЯ МОДУЛЯТОР c-MET В ФОРМЕ КРИСТАЛЛИЧЕСКОЙ L-МАЛАТНОЙ СОЛИ (ВАРИАНТЫ), СПОСОБ ЕЕ ПРОИЗВОДСТВА И СПОСОБ ЛЕЧЕНИЯ ОНКОЛОГИЧЕСКОГО ЗАБОЛЕВАНИЯ С ЕЕ ИСПОЛЬЗОВАНИЕМ |
| CN104395284A (zh) | 2011-10-20 | 2015-03-04 | 埃克塞里艾克西斯公司 | 制备喹啉衍生物的方法 |
| EP3174854B1 (en) | 2014-07-31 | 2022-08-24 | Exelixis, Inc. | Method of preparing fluorine-18 labeled cabozantinib and its analogs |
| CR20250117A (es) | 2018-01-26 | 2025-05-09 | Exelixis Inc | COMPUESTOS PARA EL TRATAMIENTO DE TRASTORNOS DEPENDIENTES DE CINASAS (Divisional 2020-0355) |
| CN117402114A (zh) * | 2018-01-26 | 2024-01-16 | 埃克塞里艾克西斯公司 | 用于治疗激酶依赖性病症的化合物 |
| CA3088198A1 (en) | 2018-01-26 | 2019-08-01 | Exelixis, Inc. | Compounds for the treatment of kinase-dependent disorders |
| KR102828472B1 (ko) * | 2018-12-13 | 2025-07-03 | 엑셀리시스, 인코포레이티드 | 키나아제 억제제의 결정질 형태 및 염 형태 |
| CN109761899B (zh) | 2019-02-14 | 2022-11-15 | 广州六顺生物科技股份有限公司 | 喹啉衍生物、其药学上可接受的盐或其溶剂合物、其应用、药物及药物组合物 |
-
2021
- 2021-04-30 CN CN202180031136.7A patent/CN115461328B/zh active Active
- 2021-04-30 MX MX2022013528A patent/MX2022013528A/es unknown
- 2021-04-30 KR KR1020227037607A patent/KR20230005190A/ko active Pending
- 2021-04-30 EP EP21727657.5A patent/EP4143169B1/en active Active
- 2021-04-30 CN CN202511511945.4A patent/CN121591655A/zh active Pending
- 2021-04-30 CA CA3176042A patent/CA3176042A1/en active Pending
- 2021-04-30 JP JP2022566135A patent/JP7728795B2/ja active Active
- 2021-04-30 AU AU2021263474A patent/AU2021263474A1/en active Pending
- 2021-04-30 US US17/922,208 patent/US12497367B2/en active Active
- 2021-04-30 PH PH1/2022/552821A patent/PH12022552821A1/en unknown
- 2021-04-30 CR CR20220551A patent/CR20220551A/es unknown
- 2021-04-30 PE PE2022002513A patent/PE20230110A1/es unknown
- 2021-04-30 WO PCT/US2021/030035 patent/WO2021222673A1/en not_active Ceased
- 2021-04-30 TW TW110115786A patent/TWI887405B/zh active
- 2021-04-30 GE GEAP202516101A patent/GEP20267875B/en unknown
- 2021-04-30 BR BR112022021712A patent/BR112022021712A2/pt unknown
-
2022
- 2022-10-26 IL IL297684A patent/IL297684B1/en unknown
- 2022-10-26 CO CONC2022/0015205A patent/CO2022015205A2/es unknown
- 2022-10-28 CL CL2022003008A patent/CL2022003008A1/es unknown
-
2025
- 2025-06-20 JP JP2025104881A patent/JP2025128388A/ja active Pending
- 2025-10-21 IL IL324105A patent/IL324105A/en unknown
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