JP2023524230A5 - - Google Patents

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Publication number
JP2023524230A5
JP2023524230A5 JP2022565835A JP2022565835A JP2023524230A5 JP 2023524230 A5 JP2023524230 A5 JP 2023524230A5 JP 2022565835 A JP2022565835 A JP 2022565835A JP 2022565835 A JP2022565835 A JP 2022565835A JP 2023524230 A5 JP2023524230 A5 JP 2023524230A5
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JP
Japan
Prior art keywords
pharmaceutically acceptable
pharmaceutical composition
stereoisomer
solvate
hydrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022565835A
Other languages
English (en)
Japanese (ja)
Other versions
JP7748392B2 (ja
JP2023524230A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2021/090718 external-priority patent/WO2021219040A1/en
Publication of JP2023524230A publication Critical patent/JP2023524230A/ja
Publication of JP2023524230A5 publication Critical patent/JP2023524230A5/ja
Application granted granted Critical
Publication of JP7748392B2 publication Critical patent/JP7748392B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022565835A 2020-04-30 2021-04-28 腫瘍微小環境における免疫調節のためのヒストンデアセチラーゼ阻害剤 Active JP7748392B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063018427P 2020-04-30 2020-04-30
US63/018,427 2020-04-30
PCT/CN2021/090718 WO2021219040A1 (en) 2020-04-30 2021-04-28 Histone deacetylase inhibitors for immunomodulation in tumor microenvironment

Publications (3)

Publication Number Publication Date
JP2023524230A JP2023524230A (ja) 2023-06-09
JP2023524230A5 true JP2023524230A5 (https=) 2023-11-07
JP7748392B2 JP7748392B2 (ja) 2025-10-02

Family

ID=78373345

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022565835A Active JP7748392B2 (ja) 2020-04-30 2021-04-28 腫瘍微小環境における免疫調節のためのヒストンデアセチラーゼ阻害剤

Country Status (16)

Country Link
US (2) US11672788B2 (https=)
EP (1) EP4142733B1 (https=)
JP (1) JP7748392B2 (https=)
KR (1) KR20230005939A (https=)
CN (1) CN116033904A (https=)
AU (1) AU2021265994B2 (https=)
BR (1) BR112022022015A2 (https=)
ES (1) ES3051512T3 (https=)
HR (1) HRP20251279T1 (https=)
IL (1) IL297687A (https=)
MX (1) MX2022013634A (https=)
NZ (1) NZ794355A (https=)
PL (1) PL4142733T3 (https=)
TW (1) TWI849310B (https=)
WO (1) WO2021219040A1 (https=)
ZA (1) ZA202212650B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115322171B (zh) * 2022-08-30 2023-03-17 深圳微芯生物科技股份有限公司 一种trka(g667c)和flt3靶点抑制剂及其与西达本胺的组合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6174905B1 (en) 1996-09-30 2001-01-16 Mitsui Chemicals, Inc. Cell differentiation inducer
EP1738752A1 (en) * 2002-12-27 2007-01-03 Schering Aktiengesellschaft Pharmaceutical combinations comprising cis-retine acid
DK1696898T3 (en) 2003-12-02 2016-02-22 Univ Ohio State Res Found ZN2 + -CHELATING DESIGN-BASED SHORT-CHAIN FAT ACIDS AS AN UNKNOWN CLASS OF HISTONDEACETYLASE INHIBITORS
CA2702536A1 (en) * 2007-10-10 2009-04-16 Orchid Research Laboratories Limited Novel histone deacetylase inhibitors
CN103880736B (zh) * 2014-04-04 2017-05-17 深圳微芯生物科技有限责任公司 一种e构型苯甲酰胺类化合物及其药用制剂与应用
CN106916101B (zh) 2017-02-15 2020-05-01 聚缘(上海)生物科技有限公司 Nampt/hdac双靶点抑制剂及其制备方法
IL264068B2 (en) * 2018-01-05 2023-07-01 Great Novel Therapeutics Biotech & Medicals Corp Aggregate and pharmaceutical preparation containing an hdac inhibitor and an nsaid aggregate together with an immune checkpoint inhibitor for use in a method for removing immunosuppression in the microenvironment of a tumor or stimulating an immune system against cancer cells

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