JP2023524039A5 - - Google Patents

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Publication number
JP2023524039A5
JP2023524039A5 JP2022566066A JP2022566066A JP2023524039A5 JP 2023524039 A5 JP2023524039 A5 JP 2023524039A5 JP 2022566066 A JP2022566066 A JP 2022566066A JP 2022566066 A JP2022566066 A JP 2022566066A JP 2023524039 A5 JP2023524039 A5 JP 2023524039A5
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JP
Japan
Prior art keywords
approximately
dose
compound
subject
formula
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022566066A
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English (en)
Japanese (ja)
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JP2023524039A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/029539 external-priority patent/WO2021222342A1/en
Publication of JP2023524039A publication Critical patent/JP2023524039A/ja
Publication of JP2023524039A5 publication Critical patent/JP2023524039A5/ja
Pending legal-status Critical Current

Links

JP2022566066A 2020-04-29 2021-04-28 T型カルシウムチャネルモジュレーターを使用する方法 Pending JP2023524039A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202063017140P 2020-04-29 2020-04-29
US63/017,140 2020-04-29
US202063050410P 2020-07-10 2020-07-10
US63/050,410 2020-07-10
US202063082946P 2020-09-24 2020-09-24
US63/082,946 2020-09-24
PCT/US2021/029539 WO2021222342A1 (en) 2020-04-29 2021-04-28 Methods of use of t-type calcium channel modulators

Publications (2)

Publication Number Publication Date
JP2023524039A JP2023524039A (ja) 2023-06-08
JP2023524039A5 true JP2023524039A5 (https=) 2024-05-09

Family

ID=78373913

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022566066A Pending JP2023524039A (ja) 2020-04-29 2021-04-28 T型カルシウムチャネルモジュレーターを使用する方法

Country Status (11)

Country Link
US (1) US20230165847A1 (https=)
EP (1) EP4142764A4 (https=)
JP (1) JP2023524039A (https=)
KR (1) KR20230018384A (https=)
CN (1) CN115776894A (https=)
AU (1) AU2021263804A1 (https=)
BR (1) BR112022021946A2 (https=)
CA (1) CA3177277A1 (https=)
IL (1) IL297642A (https=)
MX (1) MX2022013595A (https=)
WO (1) WO2021222342A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3996746A4 (en) 2019-07-11 2023-08-23 Praxis Precision Medicines, Inc. T-TYPE CALCIUM CHANNEL MODULATOR FORMULATIONS AND METHODS OF USE THEREOF
US20250170114A1 (en) * 2022-02-03 2025-05-29 Praxis Precision Medicines, Inc. Methods of treatment using t-type calcium channel modulators
WO2023192885A2 (en) * 2022-03-28 2023-10-05 Praxis Precision Medicines, Inc. Methods of using oligomeric compounds to treat scn2a-related disorders
US20250295646A1 (en) * 2022-05-09 2025-09-25 Praxis Precision Medicines, Inc. Methods of use of t-type calcium channel modulators
AU2024229946A1 (en) * 2023-03-02 2025-09-11 Praxis Precision Medicines, Inc. Crystalline salts of a t-type calcium channel modulator and methods of use thereof
CN121127456A (zh) * 2023-03-02 2025-12-12 普拉西斯精密医药公司 N-((1-(2-(叔丁基氨基)-2-氧代乙基)哌啶-4-基)甲基)-3-氯-5-氟苯甲酰胺的结晶盐形式和其使用方法
WO2025188619A1 (en) * 2024-03-04 2025-09-12 Praxis Precision Medicines, Inc. Methods of treating parkinson's disease with t-type calcium channel modulators

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8377968B2 (en) * 2008-06-02 2013-02-19 Zalicus Pharmaceuticals, Ltd. N-piperidinyl acetamide derivatives as calcium channel blockers
DK3364993T3 (da) * 2015-10-22 2023-01-09 Cavion Inc Fremgangsmåder til behandling af angelman syndrom
EP3340988B1 (en) * 2015-11-12 2025-04-09 Afasci, Inc. Ion channel inhibitory compounds, pharmaceutical formulations and uses
MX388586B (es) * 2016-12-16 2025-03-20 Idorsia Pharmaceuticals Ltd Combinacion farmaceutica que comprende un bloqueador del canal de calcio de tipo t.
WO2018118101A1 (en) * 2016-12-21 2018-06-28 Praxis Precision Medicines, Inc. T-type calcium channel modulators and methods of use thereof
MY204493A (en) * 2017-11-10 2024-08-30 Marinus Pharmaceuticals Inc Ganaxolone for use in treating genetic epileptic disorders
TWI879741B (zh) * 2018-10-03 2025-04-11 美商卡凡恩公司 以(r)-2-(4-異丙基苯基)-n-(1-(5-(2,2,2-三氟乙氧基)吡啶-2-基)乙基)乙醯胺治療自發性震顫
EP3996746A4 (en) * 2019-07-11 2023-08-23 Praxis Precision Medicines, Inc. T-TYPE CALCIUM CHANNEL MODULATOR FORMULATIONS AND METHODS OF USE THEREOF
US20250295646A1 (en) * 2022-05-09 2025-09-25 Praxis Precision Medicines, Inc. Methods of use of t-type calcium channel modulators

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