JP2023523584A5 - - Google Patents

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Publication number
JP2023523584A5
JP2023523584A5 JP2022564276A JP2022564276A JP2023523584A5 JP 2023523584 A5 JP2023523584 A5 JP 2023523584A5 JP 2022564276 A JP2022564276 A JP 2022564276A JP 2022564276 A JP2022564276 A JP 2022564276A JP 2023523584 A5 JP2023523584 A5 JP 2023523584A5
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JP
Japan
Prior art keywords
antigen
antibody
cancer
seq
binding fragment
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JP2022564276A
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English (en)
Japanese (ja)
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JP2023523584A (ja
JP7791836B2 (ja
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Priority claimed from PCT/US2021/028798 external-priority patent/WO2021216972A1/en
Publication of JP2023523584A publication Critical patent/JP2023523584A/ja
Publication of JP2023523584A5 publication Critical patent/JP2023523584A5/ja
Application granted granted Critical
Publication of JP7791836B2 publication Critical patent/JP7791836B2/ja
Active legal-status Critical Current
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JP2022564276A 2020-04-24 2021-04-23 抗cd3抗体及びその使用 Active JP7791836B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063015149P 2020-04-24 2020-04-24
US63/015,149 2020-04-24
PCT/US2021/028798 WO2021216972A1 (en) 2020-04-24 2021-04-23 Anti-cd3 antibodies and uses thereof

Publications (3)

Publication Number Publication Date
JP2023523584A JP2023523584A (ja) 2023-06-06
JP2023523584A5 true JP2023523584A5 (https=) 2024-05-02
JP7791836B2 JP7791836B2 (ja) 2025-12-24

Family

ID=78270196

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022564276A Active JP7791836B2 (ja) 2020-04-24 2021-04-23 抗cd3抗体及びその使用

Country Status (6)

Country Link
US (1) US20230212289A1 (https=)
EP (1) EP4139347A4 (https=)
JP (1) JP7791836B2 (https=)
CN (1) CN115803340A (https=)
CA (1) CA3176391A1 (https=)
WO (1) WO2021216972A1 (https=)

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Publication number Priority date Publication date Assignee Title
WO2020232247A1 (en) 2019-05-14 2020-11-19 Provention Bio, Inc. Methods and compositions for preventing type 1 diabetes
IL298999A (en) 2020-06-11 2023-02-01 Provention Bio Inc Methods and compositions for the prevention of type 1 diabetes
MX2023010541A (es) 2021-03-09 2023-11-24 Cdr Life Ag Proteinas de union al antigeno del peptido del mhc mage-a4.
US12435444B2 (en) 2021-03-09 2025-10-07 Cdr-Life Ag Rabbit-derived antigen binding protein nucleic acid libraries and methods of making the same
JP2024520444A (ja) 2021-05-24 2024-05-24 プロヴェンション・バイオ・インコーポレイテッド 1型糖尿病を治療するための方法
TWI877602B (zh) * 2022-04-21 2025-03-21 中央研究院 用於延長壽命及/或治療癌症的經基因工程化先天淋巴細胞
CA3264030A1 (en) * 2022-08-04 2024-02-08 Memorial Hospital For Cancer And Allied Diseases Anti-CD24 antibodies and their uses
CA3264474A1 (en) 2022-09-14 2024-03-21 Cdr-Life Ag MAGE-A4 DOUBLE T LYMPHOCYTE ENGAGEMENT
EP4688832A1 (en) * 2023-03-29 2026-02-11 Nanjing GenScript Biotech Co., Ltd. Antibodies and variants thereof against human cluster of differentiation 3 protein
CN116574182B (zh) * 2023-06-09 2024-02-06 上海交通大学医学院附属第九人民医院 一种抗人Ki-67抗体及其制备方法和用途
CN121293363B (zh) * 2025-12-09 2026-04-21 上海玄言生物科技有限公司 一种靶向cd14和cd3的双功能t细胞衔接器及其应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2121756A4 (en) * 2006-12-20 2011-08-31 Mmrglobal Inc ANTIBODIES AND PROCESS FOR THEIR PREPARATION AND USE
CN102796199A (zh) * 2011-05-26 2012-11-28 中国医学科学院血液病医院 抗CD3抗体Fv片段与白介素3融合蛋白突变体、制备方法及其用途
EP2892924B1 (en) * 2012-06-14 2020-11-25 Therapix Biosciences Ltd. Humanized antibodies to cluster of differentiation 3 (cd3)
CN103173478B (zh) * 2013-03-04 2015-09-09 西北大学 一种携带ptd的抗人cd3单链抗体的制备方法
CN103467605B (zh) * 2013-09-05 2015-02-04 武汉友芝友生物制药有限公司 一种cd3抗原及其制备方法和用途
RU2016132863A (ru) * 2014-01-15 2018-02-20 Займворкс Инк. БИСПЕЦИФИЧЕСКИЕ CD3 и CD19 АНТИГЕНСВЯЗЫВАЮЩИЕ КОНСТРУКЦИИ
MA40894A (fr) * 2014-11-04 2017-09-12 Glenmark Pharmaceuticals Sa Immunoglobulines hétéro-dimères reciblant des lymphocytes t cd3/cd38 et leurs procédés de production
RU2726446C2 (ru) * 2014-11-24 2020-07-14 Регенерон Фармасьютикалз, Инк. Не относящиеся к человеку животные, экспрессирующие гуманизированный комплекс cd3
US11046768B2 (en) 2017-01-27 2021-06-29 Memorial Sloan Kettering Cancer Center Bispecific HER2 and CD3 binding molecules
EA201992546A1 (ru) * 2017-04-24 2020-03-06 Мемориал Слоан Кеттеринг Кэнсер Сентер Средства на основе антител к cd33
CN111093702A (zh) * 2017-06-22 2020-05-01 财团法人生物技术开发中心 靶细胞依赖性T细胞的接合和活化型不对称异二聚Fc-ScFv融合抗体形式用于癌症治疗
PE20201265A1 (es) * 2018-03-21 2020-11-19 Alx Oncology Inc Anticuerpos contra proteina alfa reguladora de senal y metodos de uso
EP3802595A1 (en) * 2018-06-07 2021-04-14 OncoOne Research & Development GmbH Anti-oxmif/anti-cd3 antibody for cancer treatment
CN110964114B (zh) 2018-09-29 2023-07-04 上海博槿生物科技有限公司 一种双靶点抗原结合分子
JP2022508529A (ja) 2018-09-29 2022-01-19 上海博槿生物科技有限公司 二重標的抗原結合分子

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