JP2023519101A5 - - Google Patents
Info
- Publication number
- JP2023519101A5 JP2023519101A5 JP2022548612A JP2022548612A JP2023519101A5 JP 2023519101 A5 JP2023519101 A5 JP 2023519101A5 JP 2022548612 A JP2022548612 A JP 2022548612A JP 2022548612 A JP2022548612 A JP 2022548612A JP 2023519101 A5 JP2023519101 A5 JP 2023519101A5
- Authority
- JP
- Japan
- Prior art keywords
- grna
- nucleic acid
- sequence
- exon
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062975636P | 2020-02-12 | 2020-02-12 | |
| US62/975,636 | 2020-02-12 | ||
| PCT/US2021/017942 WO2021163550A1 (en) | 2020-02-12 | 2021-02-12 | Haplotype-based treatment of rp1 associated retinal degenerations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023519101A JP2023519101A (ja) | 2023-05-10 |
| JP2023519101A5 true JP2023519101A5 (enExample) | 2024-02-21 |
Family
ID=77292955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022548612A Pending JP2023519101A (ja) | 2020-02-12 | 2021-02-12 | Ｒｐ１関連網膜変性症のハプロタイプに基づく処置 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US12129496B2 (enExample) |
| EP (1) | EP4103238A4 (enExample) |
| JP (1) | JP2023519101A (enExample) |
| CN (1) | CN115427568A (enExample) |
| AU (1) | AU2021219795A1 (enExample) |
| WO (1) | WO2021163550A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12171813B2 (en) | 2021-02-05 | 2024-12-24 | Christiana Care Gene Editing Institute, Inc. | Methods of and compositions for reducing gene expression and/or activity |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3023787A1 (de) | 1980-06-25 | 1982-01-21 | Studiengesellschaft Kohle mbH, 4330 Mülheim | Verfahren zur erhoehung der inkorporation und der expression von genetischem material in die kerne von intakten zellen mit hilfe von liposomen |
| JPS57124055A (en) | 1981-01-27 | 1982-08-02 | Toyota Motor Corp | Air-fuel ratio control device for engine |
| AU6131086A (en) | 1985-07-05 | 1987-01-30 | Whitehead Institute For Biomedical Research | Epithelial cells expressing foreign genetic material |
| US4980286A (en) | 1985-07-05 | 1990-12-25 | Whitehead Institute For Biomedical Research | In vivo introduction and expression of foreign genetic material in epithelial cells |
| DE3852823T2 (de) | 1987-09-11 | 1995-05-24 | Hughes Howard Med Inst | Transduktionsveränderte fibroblasten und ihre anwendung. |
| JP2914692B2 (ja) | 1987-12-11 | 1999-07-05 | ホワイトヘツド・インスチチユート・フオー・バイオメデイカル・リサーチ | 内皮細胞の遺伝子修飾 |
| EP0400047B1 (en) | 1988-02-05 | 1997-04-23 | Whitehead Institute For Biomedical Research | Modified hepatocytes and uses therefor |
| EP0452457B1 (en) | 1989-11-03 | 1997-08-20 | Vanderbilt University | Method of in vivo delivery of functioning foreign genes |
| EP0556345B2 (en) | 1990-10-31 | 2005-10-12 | Cell Genesys, Inc. | Retroviral vectors useful for gene therapy |
| US10378027B2 (en) | 2013-03-15 | 2019-08-13 | The General Hospital Corporation | RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci |
| NZ718926A (en) | 2013-10-11 | 2021-12-24 | Massachusetts Eye & Ear Infirmary | Methods of predicting ancestral virus sequences and uses thereof |
| JP6817215B2 (ja) | 2015-03-03 | 2021-01-20 | ザ ジェネラル ホスピタル コーポレイション | 変更ＰＡＭ特異性を有する遺伝子操作ＣＲＩＳＰＲ−Ｃａｓ９ヌクレアーゼ |
| AU2016316845B2 (en) | 2015-08-28 | 2022-03-10 | The General Hospital Corporation | Engineered CRISPR-Cas9 nucleases |
| CA3032822A1 (en) * | 2016-08-02 | 2018-02-08 | Editas Medicine, Inc. | Compositions and methods for treating cep290 associated disease |
| WO2019165322A1 (en) | 2018-02-22 | 2019-08-29 | Moore Tara | Crispr/cas9 systems, and methods of use thereof |
| WO2018148246A1 (en) * | 2017-02-07 | 2018-08-16 | Massachusetts Institute Of Technology | Methods and compositions for rna-guided genetic circuits |
| ES2992912T3 (en) | 2017-04-21 | 2024-12-19 | Massachusetts Gen Hospital | Variants of cpf1 (cas12a) with altered pam specificity |
| US20210017509A1 (en) * | 2018-03-23 | 2021-01-21 | The Trustees Of Columbia University In The City Of New York | Gene Editing for Autosomal Dominant Diseases |
| AU2019237541B2 (en) | 2018-03-23 | 2025-02-13 | Editas Medicine, Inc. | CRISPR/Cas9-mediated exon-skipping approach for USH2A-associated Usher syndrome |
-
2021
- 2021-02-12 US US17/175,234 patent/US12129496B2/en active Active
- 2021-02-12 EP EP21753483.3A patent/EP4103238A4/en active Pending
- 2021-02-12 WO PCT/US2021/017942 patent/WO2021163550A1/en not_active Ceased
- 2021-02-12 AU AU2021219795A patent/AU2021219795A1/en active Pending
- 2021-02-12 CN CN202180027183.4A patent/CN115427568A/zh active Pending
- 2021-02-12 JP JP2022548612A patent/JP2023519101A/ja active Pending
-
2024
- 2024-09-19 US US18/890,708 patent/US20250115887A1/en active Pending
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