JP2023518775A5 - - Google Patents

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Publication number
JP2023518775A5
JP2023518775A5 JP2022556473A JP2022556473A JP2023518775A5 JP 2023518775 A5 JP2023518775 A5 JP 2023518775A5 JP 2022556473 A JP2022556473 A JP 2022556473A JP 2022556473 A JP2022556473 A JP 2022556473A JP 2023518775 A5 JP2023518775 A5 JP 2023518775A5
Authority
JP
Japan
Prior art keywords
compound according
heteroaryl
aryl
substituted
injury
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022556473A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023518775A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2021/083015 external-priority patent/WO2021190603A1/en
Publication of JP2023518775A publication Critical patent/JP2023518775A/ja
Publication of JP2023518775A5 publication Critical patent/JP2023518775A5/ja
Pending legal-status Critical Current

Links

JP2022556473A 2020-03-26 2021-03-25 シクロフィリン阻害剤およびその使用 Pending JP2023518775A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2020/081296 2020-03-26
CN2020081296 2020-03-26
PCT/CN2021/083015 WO2021190603A1 (en) 2020-03-26 2021-03-25 Cyclophilin inhibitors and uses thereof

Publications (2)

Publication Number Publication Date
JP2023518775A JP2023518775A (ja) 2023-05-08
JP2023518775A5 true JP2023518775A5 (https=) 2024-04-05

Family

ID=77891508

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022556473A Pending JP2023518775A (ja) 2020-03-26 2021-03-25 シクロフィリン阻害剤およびその使用

Country Status (9)

Country Link
US (1) US20230203099A1 (https=)
EP (1) EP4126903A4 (https=)
JP (1) JP2023518775A (https=)
KR (1) KR20220158759A (https=)
CN (1) CN115315432A (https=)
AU (1) AU2021244763A1 (https=)
CA (1) CA3172689A1 (https=)
TW (1) TW202144378A (https=)
WO (1) WO2021190603A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111449050A (zh) * 2019-01-20 2020-07-28 睿诺医疗科技(上海)有限公司 环孢菌素类似物及其用途
AU2020363688A1 (en) 2019-10-12 2022-04-21 Farsight Medical Technology (Shanghai) Co., Ltd. Treatment and prevention of nephrotoxin-induced kidney injuries
AU2021256222A1 (en) 2020-04-15 2022-10-06 Farsight Medical Technology (Shanghai) Co., Ltd. Prevention and treatment of organ injuries
CN115028679B (zh) * 2022-08-11 2022-11-15 深圳湾实验室 一种具有Cyclophilin A降解活性的PROTAC化合物及其制备方法与应用
CN115028681B (zh) * 2022-08-11 2022-11-15 中国科学院微生物研究所 一种降解亲环素a的嵌合体化合物及其制备方法与应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6809077B2 (en) * 2001-10-12 2004-10-26 Enanta Pharmaceuticals, Inc. Cyclosporin analogs for the treatment of autoimmune diseases
US7538084B2 (en) * 2003-03-17 2009-05-26 Amr Technology, Inc. Cyclosporins
AU2009276241A1 (en) * 2008-07-30 2010-02-04 Ciclofilin Pharmaceuticals Corp. Nonimmunosuppressive cyclosporine analogue molecules
BR112013014890B1 (pt) * 2010-12-15 2023-10-24 Contravir Pharmaceuticals, Inc Composto análogo de moléculas pertencentes à família ciclosporina, composição farmacêutica compreendendo o mesmo, uso terapêutico ou profilático do referido composto e processos para a preparação dos mesmos
GB201414806D0 (en) * 2014-08-20 2014-10-01 Ucl Business Plc Cyclosporin conjugates
CN118324867A (zh) * 2016-05-17 2024-07-12 美国科技环球有限公司 新型环孢菌素衍生物及其用途
GB201711749D0 (en) * 2017-07-21 2017-09-06 Cypralis Ltd Cyclosporin analogues and uses thereof
AU2020363688A1 (en) * 2019-10-12 2022-04-21 Farsight Medical Technology (Shanghai) Co., Ltd. Treatment and prevention of nephrotoxin-induced kidney injuries

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