AU2021244763A1 - Cyclophilin inhibitors and uses thereof - Google Patents
Cyclophilin inhibitors and uses thereof Download PDFInfo
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- AU2021244763A1 AU2021244763A1 AU2021244763A AU2021244763A AU2021244763A1 AU 2021244763 A1 AU2021244763 A1 AU 2021244763A1 AU 2021244763 A AU2021244763 A AU 2021244763A AU 2021244763 A AU2021244763 A AU 2021244763A AU 2021244763 A1 AU2021244763 A1 AU 2021244763A1
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2020/081296 | 2020-03-26 | ||
| CN2020081296 | 2020-03-26 | ||
| PCT/CN2021/083015 WO2021190603A1 (en) | 2020-03-26 | 2021-03-25 | Cyclophilin inhibitors and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2021244763A1 true AU2021244763A1 (en) | 2022-10-06 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2021244763A Abandoned AU2021244763A1 (en) | 2020-03-26 | 2021-03-25 | Cyclophilin inhibitors and uses thereof |
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| Country | Link |
|---|---|
| US (1) | US20230203099A1 (https=) |
| EP (1) | EP4126903A4 (https=) |
| JP (1) | JP2023518775A (https=) |
| KR (1) | KR20220158759A (https=) |
| CN (1) | CN115315432A (https=) |
| AU (1) | AU2021244763A1 (https=) |
| CA (1) | CA3172689A1 (https=) |
| TW (1) | TW202144378A (https=) |
| WO (1) | WO2021190603A1 (https=) |
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| CN111449050A (zh) * | 2019-01-20 | 2020-07-28 | 睿诺医疗科技（上海）有限公司 | 环孢菌素类似物及其用途 |
| AU2020363688A1 (en) | 2019-10-12 | 2022-04-21 | Farsight Medical Technology (Shanghai) Co., Ltd. | Treatment and prevention of nephrotoxin-induced kidney injuries |
| AU2021256222A1 (en) | 2020-04-15 | 2022-10-06 | Farsight Medical Technology (Shanghai) Co., Ltd. | Prevention and treatment of organ injuries |
| CN115028679B (zh) * | 2022-08-11 | 2022-11-15 | 深圳湾实验室 | 一种具有Cyclophilin A降解活性的PROTAC化合物及其制备方法与应用 |
| CN115028681B (zh) * | 2022-08-11 | 2022-11-15 | 中国科学院微生物研究所 | 一种降解亲环素a的嵌合体化合物及其制备方法与应用 |
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| US6809077B2 (en) * | 2001-10-12 | 2004-10-26 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogs for the treatment of autoimmune diseases |
| US7538084B2 (en) * | 2003-03-17 | 2009-05-26 | Amr Technology, Inc. | Cyclosporins |
| AU2009276241A1 (en) * | 2008-07-30 | 2010-02-04 | Ciclofilin Pharmaceuticals Corp. | Nonimmunosuppressive cyclosporine analogue molecules |
| BR112013014890B1 (pt) * | 2010-12-15 | 2023-10-24 | Contravir Pharmaceuticals, Inc | Composto análogo de moléculas pertencentes à família ciclosporina, composição farmacêutica compreendendo o mesmo, uso terapêutico ou profilático do referido composto e processos para a preparação dos mesmos |
| GB201414806D0 (en) * | 2014-08-20 | 2014-10-01 | Ucl Business Plc | Cyclosporin conjugates |
| CN118324867A (zh) * | 2016-05-17 | 2024-07-12 | 美国科技环球有限公司 | 新型环孢菌素衍生物及其用途 |
| GB201711749D0 (en) * | 2017-07-21 | 2017-09-06 | Cypralis Ltd | Cyclosporin analogues and uses thereof |
| AU2020363688A1 (en) * | 2019-10-12 | 2022-04-21 | Farsight Medical Technology (Shanghai) Co., Ltd. | Treatment and prevention of nephrotoxin-induced kidney injuries |
-
2021
- 2021-03-25 TW TW110110798A patent/TW202144378A/zh unknown
- 2021-03-25 CN CN202180023173.3A patent/CN115315432A/zh active Pending
- 2021-03-25 US US17/906,978 patent/US20230203099A1/en not_active Abandoned
- 2021-03-25 WO PCT/CN2021/083015 patent/WO2021190603A1/en not_active Ceased
- 2021-03-25 AU AU2021244763A patent/AU2021244763A1/en not_active Abandoned
- 2021-03-25 CA CA3172689A patent/CA3172689A1/en active Pending
- 2021-03-25 KR KR1020227036425A patent/KR20220158759A/ko not_active Withdrawn
- 2021-03-25 JP JP2022556473A patent/JP2023518775A/ja active Pending
- 2021-03-25 EP EP21774048.9A patent/EP4126903A4/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP4126903A1 (en) | 2023-02-08 |
| KR20220158759A (ko) | 2022-12-01 |
| WO2021190603A1 (en) | 2021-09-30 |
| CA3172689A1 (en) | 2021-09-30 |
| JP2023518775A (ja) | 2023-05-08 |
| US20230203099A1 (en) | 2023-06-29 |
| CN115315432A (zh) | 2022-11-08 |
| EP4126903A4 (en) | 2024-05-08 |
| TW202144378A (zh) | 2021-12-01 |
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| MK1 | Application lapsed section 142(2)(a) - no request for examination in relevant period |