JP2023516380A5 - - Google Patents

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Publication number
JP2023516380A5
JP2023516380A5 JP2022552781A JP2022552781A JP2023516380A5 JP 2023516380 A5 JP2023516380 A5 JP 2023516380A5 JP 2022552781 A JP2022552781 A JP 2022552781A JP 2022552781 A JP2022552781 A JP 2022552781A JP 2023516380 A5 JP2023516380 A5 JP 2023516380A5
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JP
Japan
Prior art keywords
immunoglobulin
constant region
region
protease
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022552781A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023516380A (ja
JP7766608B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/055673 external-priority patent/WO2021176090A1/en
Publication of JP2023516380A publication Critical patent/JP2023516380A/ja
Publication of JP2023516380A5 publication Critical patent/JP2023516380A5/ja
Application granted granted Critical
Publication of JP7766608B2 publication Critical patent/JP7766608B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2022552781A 2020-03-05 2021-03-05 プロテアーゼプロセシングした分子 Active JP7766608B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20305233.7 2020-03-05
EP20305233 2020-03-05
PCT/EP2021/055673 WO2021176090A1 (en) 2020-03-05 2021-03-05 Protease-processed molecules

Publications (3)

Publication Number Publication Date
JP2023516380A JP2023516380A (ja) 2023-04-19
JP2023516380A5 true JP2023516380A5 (enExample) 2024-03-11
JP7766608B2 JP7766608B2 (ja) 2025-11-10

Family

ID=71096648

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022552781A Active JP7766608B2 (ja) 2020-03-05 2021-03-05 プロテアーゼプロセシングした分子

Country Status (15)

Country Link
US (1) US20230279151A1 (enExample)
EP (1) EP4114865B1 (enExample)
JP (1) JP7766608B2 (enExample)
KR (1) KR20220150345A (enExample)
CN (1) CN115210265A (enExample)
AU (1) AU2021231327A1 (enExample)
BR (1) BR112022017542A2 (enExample)
CA (1) CA3170452A1 (enExample)
DK (1) DK4114865T3 (enExample)
ES (1) ES3068539T3 (enExample)
IL (1) IL295958A (enExample)
MX (1) MX2022010958A (enExample)
PL (1) PL4114865T3 (enExample)
TW (1) TW202146463A (enExample)
WO (1) WO2021176090A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025199278A2 (en) * 2024-03-20 2025-09-25 Regeneron Pharmaceuticals, Inc. Masked multispecific antigen-binding molecules with cleavable linkers

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060252096A1 (en) * 2005-04-26 2006-11-09 Glycofi, Inc. Single chain antibody with cleavable linker
EP2050764A1 (en) 2007-10-15 2009-04-22 sanofi-aventis Novel polyvalent bispecific antibody format and uses thereof
CN103068846B9 (zh) * 2010-08-24 2016-09-28 弗·哈夫曼-拉罗切有限公司 包含二硫键稳定性Fv片段的双特异性抗体
CN112225798B (zh) * 2011-05-17 2023-07-18 洛克菲勒大学 人类免疫缺陷病毒中和抗体及其使用方法
EP2729488A4 (en) * 2011-07-06 2015-01-14 Medimmune Llc PROCESS FOR PREPARING MULTIMANT POLYPEPTIDES
KR101963230B1 (ko) * 2011-12-26 2019-03-29 삼성전자주식회사 복수개의 단일 항체를 포함하는 단백질 복합체
EP3197916A2 (en) * 2014-09-25 2017-08-02 Amgen Inc. Protease-activatable bispecific proteins
EP3443006B1 (en) 2016-04-13 2023-08-02 Sanofi Trispecific and/or trivalent binding proteins

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