JP2023515670A5 - - Google Patents
Info
- Publication number
- JP2023515670A5 JP2023515670A5 JP2022552549A JP2022552549A JP2023515670A5 JP 2023515670 A5 JP2023515670 A5 JP 2023515670A5 JP 2022552549 A JP2022552549 A JP 2022552549A JP 2022552549 A JP2022552549 A JP 2022552549A JP 2023515670 A5 JP2023515670 A5 JP 2023515670A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- protein
- aptamer
- nucleic acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062984618P | 2020-03-03 | 2020-03-03 | |
| US62/984,618 | 2020-03-03 | ||
| US202163146447P | 2021-02-05 | 2021-02-05 | |
| US63/146,447 | 2021-02-05 | ||
| PCT/US2021/020513 WO2021178432A1 (en) | 2020-03-03 | 2021-03-02 | Rna-guided genome recombineering at kilobase scale |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023515670A JP2023515670A (ja) | 2023-04-13 |
| JP2023515670A5 true JP2023515670A5 (OSRAM) | 2024-03-07 |
Family
ID=77614129
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022552549A Pending JP2023515670A (ja) | 2020-03-03 | 2021-03-02 | キロ塩基スケールでのｒｎａガイドゲノムリコンビニアリング |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230091242A1 (OSRAM) |
| EP (1) | EP4114845A4 (OSRAM) |
| JP (1) | JP2023515670A (OSRAM) |
| KR (1) | KR20220151175A (OSRAM) |
| CN (1) | CN115667283A (OSRAM) |
| AU (1) | AU2021231769A1 (OSRAM) |
| BR (1) | BR112022017196A2 (OSRAM) |
| CA (1) | CA3173526A1 (OSRAM) |
| IL (1) | IL296057A (OSRAM) |
| MX (1) | MX2022010835A (OSRAM) |
| WO (1) | WO2021178432A1 (OSRAM) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2024002482A (es) * | 2021-09-01 | 2024-09-19 | Univ Leland Stanford Junior | Recombinacion del genoma guiada por arn en escala de kilobase. |
| WO2023154892A1 (en) * | 2022-02-10 | 2023-08-17 | Possible Medicines Llc | Rna-guided genome recombineering at kilobase scale |
| WO2023154877A2 (en) * | 2022-02-10 | 2023-08-17 | The Board Of Trustees Of The Leland Stanford Junior University | Rna-guided genome recombineering at kilobase scale |
| WO2024168265A1 (en) * | 2023-02-10 | 2024-08-15 | Possible Medicines Llc | Aav delivery of rna guided recombination system |
| WO2024168253A1 (en) * | 2023-02-10 | 2024-08-15 | Possible Medicines Llc | Delivery of an rna guided recombination system |
| CN117025670A (zh) * | 2023-03-13 | 2023-11-10 | 苏州金唯智生物科技有限公司 | 一种检测CRISPR-Cas产生的DNA双链断裂位点的方法 |
| CN120555441B (zh) * | 2025-05-29 | 2026-04-17 | 西北农林科技大学 | 基于CtIP蛋白提高CRISPR/Cas9介导的外源基因整合效率的DNA适配体及其应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69841340D1 (de) * | 1997-12-05 | 2010-01-07 | Europ Lab Molekularbiolog | Neue Methode zur Klonierung DNS unter Anwendung des E. coli RecE/RecT Rekombinationssystems |
| US9388430B2 (en) * | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
| WO2016022363A2 (en) * | 2014-07-30 | 2016-02-11 | President And Fellows Of Harvard College | Cas9 proteins including ligand-dependent inteins |
| JP6817215B2 (ja) * | 2015-03-03 | 2021-01-20 | ザ ジェネラル ホスピタル コーポレイション | 変更ＰＡＭ特異性を有する遺伝子操作ＣＲＩＳＰＲ−Ｃａｓ９ヌクレアーゼ |
| WO2016205759A1 (en) * | 2015-06-18 | 2016-12-22 | The Broad Institute Inc. | Engineering and optimization of systems, methods, enzymes and guide scaffolds of cas9 orthologs and variants for sequence manipulation |
| JP7044373B2 (ja) * | 2015-07-15 | 2022-03-30 | ラトガース，ザ ステート ユニバーシティ オブ ニュージャージー | ヌクレアーゼ非依存的な標的化遺伝子編集プラットフォームおよびその用途 |
| WO2019089910A1 (en) * | 2017-11-01 | 2019-05-09 | Ohio State Innovation Foundation | Highly compact cas9-based transcriptional regulators for in vivo gene regulation |
| KR102098915B1 (ko) * | 2017-12-22 | 2020-04-09 | (주)지플러스 생명과학 | 키메라 게놈 조작 분자 및 방법 |
| MX2024002482A (es) * | 2021-09-01 | 2024-09-19 | Univ Leland Stanford Junior | Recombinacion del genoma guiada por arn en escala de kilobase. |
-
2021
- 2021-03-02 EP EP21764351.9A patent/EP4114845A4/en active Pending
- 2021-03-02 BR BR112022017196A patent/BR112022017196A2/pt unknown
- 2021-03-02 AU AU2021231769A patent/AU2021231769A1/en active Pending
- 2021-03-02 CA CA3173526A patent/CA3173526A1/en active Pending
- 2021-03-02 US US17/905,457 patent/US20230091242A1/en active Pending
- 2021-03-02 JP JP2022552549A patent/JP2023515670A/ja active Pending
- 2021-03-02 WO PCT/US2021/020513 patent/WO2021178432A1/en not_active Ceased
- 2021-03-02 CN CN202180033011.8A patent/CN115667283A/zh active Pending
- 2021-03-02 KR KR1020227033540A patent/KR20220151175A/ko active Pending
- 2021-03-02 MX MX2022010835A patent/MX2022010835A/es unknown
- 2021-03-02 IL IL296057A patent/IL296057A/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Wolffe | Structural and functional properties of the evolutionarily ancient Y‐box family of nucleic acid binding proteins | |
| JP2023126956A (ja) | 望ましくないオフターゲット塩基エディター脱アミノ化を制限するためのスプリットデアミナーゼの使用 | |
| US20190382775A1 (en) | Truncated crispr-cas proteins for dna targeting | |
| JP2024028863A (ja) | エピジェネティックに調節される部位特異的ヌクレアーゼ | |
| JP2023541400A5 (OSRAM) | ||
| JP2022519507A5 (OSRAM) | ||
| JP2024083479A5 (OSRAM) | ||
| IL309801B2 (en) | Using nucleosome interacting protein domains to enhance targeted genome modification | |
| JP2023520504A5 (OSRAM) | ||
| JP2025505732A5 (OSRAM) | ||
| JP2023516226A5 (OSRAM) | ||
| JP2025510586A5 (OSRAM) | ||
| JP2022539338A5 (OSRAM) | ||
| JP2024511163A5 (OSRAM) | ||
| US20240254464A1 (en) | Cleavage-inactive cas12f1, cleavage-inactive cas12f1-based fusion protein, crispr gene-editing system comprising same, and preparation method and use thereof | |
| JP2018528237A5 (OSRAM) | ||
| JP2022513141A5 (OSRAM) | ||
| WO2003091429A1 (en) | Antimicrobial polypeptide and utizliation thereof | |
| Han et al. | Nanobiomotors of archaeal DNA repair machineries: current research status and application potential | |
| WO2026011782A1 (zh) | 抑制FXI基因表达的siRNA的制备方法 | |
| US20100184949A1 (en) | Method for the mass expression of an antimicrobial peptide by using a translational coupling system | |
| CN103764820A (zh) | 序列特异性工程改造的核糖核酸酶h和用于确定dna-rna杂交物结合蛋白序列偏好的方法 | |
| JP2025535373A5 (OSRAM) | ||
| CN112029741B (zh) | 银杏中生长素n糖基转移酶蛋白及其编码基因与应用 | |
| KR101286733B1 (ko) | 세포표면에서 발현되는 항균 펩타이드 다중합체 |