JP2023513373A5 - - Google Patents

Info

Publication number
JP2023513373A5
JP2023513373A5 JP2022548875A JP2022548875A JP2023513373A5 JP 2023513373 A5 JP2023513373 A5 JP 2023513373A5 JP 2022548875 A JP2022548875 A JP 2022548875A JP 2022548875 A JP2022548875 A JP 2022548875A JP 2023513373 A5 JP2023513373 A5 JP 2023513373A5
Authority
JP
Japan
Prior art keywords
pharmaceutically acceptable
compound according
solvate
acceptable salt
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2022548875A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023513373A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2021/000091 external-priority patent/WO2021161105A1/en
Publication of JP2023513373A publication Critical patent/JP2023513373A/ja
Publication of JP2023513373A5 publication Critical patent/JP2023513373A5/ja
Ceased legal-status Critical Current

Links

JP2022548875A 2020-02-14 2021-02-12 P2x3修飾薬 Ceased JP2023513373A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062977008P 2020-02-14 2020-02-14
US62/977,008 2020-02-14
PCT/IB2021/000091 WO2021161105A1 (en) 2020-02-14 2021-02-12 P2x3 modulators

Publications (2)

Publication Number Publication Date
JP2023513373A JP2023513373A (ja) 2023-03-30
JP2023513373A5 true JP2023513373A5 (enExample) 2024-02-20

Family

ID=77292083

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022548875A Ceased JP2023513373A (ja) 2020-02-14 2021-02-12 P2x3修飾薬

Country Status (11)

Country Link
US (1) US20230312557A1 (enExample)
EP (1) EP4103564A4 (enExample)
JP (1) JP2023513373A (enExample)
KR (1) KR20220141331A (enExample)
CN (2) CN119039290A (enExample)
AU (1) AU2021219097A1 (enExample)
BR (1) BR112022015858A2 (enExample)
CA (1) CA3170664A1 (enExample)
IL (1) IL295393A (enExample)
MX (1) MX2022009762A (enExample)
WO (1) WO2021161105A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7578602B2 (ja) 2019-02-25 2024-11-06 グラクソスミスクライン、インテレクチュアル、プロパティー、(ナンバー3)、リミテッド P2x3修飾薬での治療
CN115427419B (zh) * 2020-02-14 2026-04-21 葛兰素史密斯克莱知识产权(第3号)有限公司 P2x3拮抗剂的制备
WO2021244634A1 (zh) * 2020-06-05 2021-12-09 武汉人福创新药物研发中心有限公司 咪唑并吡啶类化合物及其用途
WO2022156783A1 (zh) * 2021-01-22 2022-07-28 武汉人福创新药物研发中心有限公司 咪唑并吡啶类化合物的制备方法及其中间体
CN114805237B (zh) * 2021-01-22 2026-04-21 武汉人福创新药物研发中心有限公司 杂环类化合物的制备方法及其中间体
WO2022161462A1 (zh) * 2021-01-29 2022-08-04 上海海雁医药科技有限公司 吗啉衍生物及其药物组合物和用途
CN115043836B (zh) * 2021-08-20 2023-07-18 苏州璞正医药有限公司 一种咪唑并吡啶衍生物的p2x3受体选择性调节剂及其药物用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2012DN03391A (enExample) * 2009-11-18 2015-10-23 Astrazeneca Ab
DK3381917T3 (da) * 2013-01-31 2021-10-18 Bellus Health Cough Inc Imidazopyridinforbindelser og anvendelser deraf
US9907795B2 (en) * 2016-01-08 2018-03-06 Nerre Therapeutics Limited Method of treatment of chronic cough administering orvepitant in combination with other therapeutic agents
US10111883B1 (en) * 2017-09-18 2018-10-30 Bellus Health Cough Inc. Selective P2X3 modulators
IL282087B2 (en) * 2018-10-10 2025-11-01 Bellus Health Cough Inc 4-(imidazo[1,2-a]pyridin-3-yl)-benzamide derivatives for treating pruritus
KR102797127B1 (ko) * 2018-12-29 2025-04-21 우한 크리에이터나 사이언스 앤드 테크놀로지 컴퍼니, 리미티드 헤테로고리계 화합물, 중간체, 이의 제조 방법 및 용도
JP7578602B2 (ja) * 2019-02-25 2024-11-06 グラクソスミスクライン、インテレクチュアル、プロパティー、(ナンバー3)、リミテッド P2x3修飾薬での治療
CN112409331B (zh) * 2019-08-21 2024-02-20 上海翰森生物医药科技有限公司 杂环类衍生物抑制剂、其制备方法和应用

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