JP2023512654A - Ｐｄ－１軸結合アンタゴニストおよびｒｎａワクチンを用いてネオエピトープ特異的ｔ細胞を誘導する方法 - Google Patents

Ｐｄ－１軸結合アンタゴニストおよびｒｎａワクチンを用いてネオエピトープ特異的ｔ細胞を誘導する方法 Download PDF

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JP2023512654A
JP2023512654A JP2022545335A JP2022545335A JP2023512654A JP 2023512654 A JP2023512654 A JP 2023512654A JP 2022545335 A JP2022545335 A JP 2022545335A JP 2022545335 A JP2022545335 A JP 2022545335A JP 2023512654 A JP2023512654 A JP 2023512654A
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individual
rna vaccine
tumor
specific
cells
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JP2023512654A5 (https=
Inventor
ラルス ミューラー，
レイチェル ルボン サバド，
マヘーシュ ヤーダヴ，
チンピン チャン，
ウグル シャヒン，
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Biontech SE
Genentech Inc
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Biontech SE
Genentech Inc
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K40/00—Cellular immunotherapy
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
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JP2022545335A 2020-01-31 2021-01-29 Ｐｄ－１軸結合アンタゴニストおよびｒｎａワクチンを用いてネオエピトープ特異的ｔ細胞を誘導する方法 Pending JP2023512654A (ja)

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Application Number Priority Date Filing Date Title
US202062968818P 2020-01-31 2020-01-31
US62/968,818 2020-01-31
US202063041707P 2020-06-19 2020-06-19
US63/041,707 2020-06-19
PCT/US2021/015710 WO2021155149A1 (en) 2020-01-31 2021-01-29 Methods of inducing neoepitope-specific t cells with a pd-1 axis binding antagonist and an rna vaccine

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JP2023512654A true JP2023512654A (ja) 2023-03-28
JP2023512654A5 JP2023512654A5 (https=) 2024-02-06

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US (1) US20220378910A1 (https=)
EP (1) EP4096708A1 (https=)
JP (1) JP2023512654A (https=)
KR (1) KR20220136378A (https=)
CN (2) CN115397459A (https=)
AU (1) AU2021212197A1 (https=)
BR (1) BR112022015077A2 (https=)
CA (1) CA3164559A1 (https=)
IL (1) IL294859A (https=)
MX (1) MX2022009391A (https=)
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WO (1) WO2021155149A1 (https=)

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AU2016341309A1 (en) 2015-10-22 2018-06-07 Modernatx, Inc. Cancer vaccines
WO2023196232A1 (en) * 2022-04-04 2023-10-12 University Of Florida Research Foundation, Inc. Method of characterizing tumors
WO2023237726A1 (en) 2022-06-10 2023-12-14 Pantarhei Oncology B.V. An intracellular tumor-specific variant of human zona pellucida glycoprotein 3 and nucleic acids coding therefor for use in the treatment of cancer

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