JP2023510870A5 - - Google Patents

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Publication number
JP2023510870A5
JP2023510870A5 JP2022542896A JP2022542896A JP2023510870A5 JP 2023510870 A5 JP2023510870 A5 JP 2023510870A5 JP 2022542896 A JP2022542896 A JP 2022542896A JP 2022542896 A JP2022542896 A JP 2022542896A JP 2023510870 A5 JP2023510870 A5 JP 2023510870A5
Authority
JP
Japan
Prior art keywords
human
seq
stat3
polypeptide
modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022542896A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023510870A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/013519 external-priority patent/WO2021146485A2/en
Publication of JP2023510870A publication Critical patent/JP2023510870A/ja
Publication of JP2023510870A5 publication Critical patent/JP2023510870A5/ja
Priority to JP2025277551A priority Critical patent/JP2026053539A/ja
Pending legal-status Critical Current

Links

JP2022542896A 2020-01-14 2021-01-14 Ｉｃｄ ｓｔａｔシグナル伝達が改変されたｃｄ１２２ Pending JP2023510870A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025277551A JP2026053539A (ja) 2020-01-14 2025-12-23 Ｉｃｄ ｓｔａｔシグナル伝達が改変されたｃｄ１２２

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062961157P 2020-01-14 2020-01-14
US62/961,157 2020-01-14
PCT/US2021/013519 WO2021146485A2 (en) 2020-01-14 2021-01-14 Cd122 with altered icd stat signaling

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025277551A Division JP2026053539A (ja) 2020-01-14 2025-12-23 Ｉｃｄ ｓｔａｔシグナル伝達が改変されたｃｄ１２２

Publications (2)

Publication Number Publication Date
JP2023510870A JP2023510870A (ja) 2023-03-15
JP2023510870A5 true JP2023510870A5 (https=) 2024-01-22

Family

ID=76863264

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022542896A Pending JP2023510870A (ja) 2020-01-14 2021-01-14 Ｉｃｄ ｓｔａｔシグナル伝達が改変されたｃｄ１２２
JP2025277551A Pending JP2026053539A (ja) 2020-01-14 2025-12-23 Ｉｃｄ ｓｔａｔシグナル伝達が改変されたｃｄ１２２

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025277551A Pending JP2026053539A (ja) 2020-01-14 2025-12-23 Ｉｃｄ ｓｔａｔシグナル伝達が改変されたｃｄ１２２

Country Status (10)

Country Link
US (1) US20230027899A1 (https=)
EP (1) EP4090339A4 (https=)
JP (2) JP2023510870A (https=)
KR (1) KR20220131529A (https=)
CN (1) CN115038453A (https=)
AU (1) AU2021208559A1 (https=)
CA (1) CA3165753A1 (https=)
IL (1) IL293822A (https=)
MX (1) MX2022008769A (https=)
WO (1) WO2021146485A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102777151B1 (ko) 2017-11-21 2025-03-05 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 인터루킨-2의 부분 효능제
WO2021146436A2 (en) 2020-01-14 2021-07-22 Synthekine, Inc. Biased il2 muteins methods and compositions
CA3179414A1 (en) * 2020-04-06 2021-10-14 Synthekine, Inc. Human immune cells genomically modified to express orthogonal receptors
WO2024235281A1 (zh) * 2023-05-17 2024-11-21 北京晶泰科技有限公司 白细胞介素-2变体及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2869459T3 (es) * 2014-05-16 2021-10-25 Medimmune Llc Moléculas con unión a receptor de fc de neonato alterada que tiene propiedades terapéuticas y de diagnóstico potenciadas
WO2016127257A1 (en) * 2015-02-12 2016-08-18 University Health Network Chimeric antigen receptors
US11655452B2 (en) * 2015-06-25 2023-05-23 Icell Gene Therapeutics Inc. Chimeric antigen receptors (CARs), compositions and methods of use thereof
CN117659160A (zh) * 2015-09-11 2024-03-08 小利兰·斯坦福大学托管委员会 生物相关正交细胞因子/受体对
WO2018035387A1 (en) * 2016-08-17 2018-02-22 The Broad Institute, Inc. Novel crispr enzymes and systems
CN121517534A (zh) * 2019-12-13 2026-02-13 辛德凯因股份有限公司 Il-2直向同源物及其使用方法
KR20220141299A (ko) * 2020-01-14 2022-10-19 신테카인, 인크. Il2 오르토로그 및 사용 방법
US20230159892A1 (en) * 2020-04-06 2023-05-25 Synthekine, Inc. Engineered immune cells
KR20240154656A (ko) * 2022-03-08 2024-10-25 신테카인, 인크. 직교 gpc3 키메라 항원 수용체 t 세포

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