JP2023509421A5 - - Google Patents
Info
- Publication number
- JP2023509421A5 JP2023509421A5 JP2022540327A JP2022540327A JP2023509421A5 JP 2023509421 A5 JP2023509421 A5 JP 2023509421A5 JP 2022540327 A JP2022540327 A JP 2022540327A JP 2022540327 A JP2022540327 A JP 2022540327A JP 2023509421 A5 JP2023509421 A5 JP 2023509421A5
- Authority
- JP
- Japan
- Prior art keywords
- independently selected
- group
- alkyl
- substituted
- ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Revoked
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962955853P | 2019-12-31 | 2019-12-31 | |
| US62/955,853 | 2019-12-31 | ||
| US202063090547P | 2020-10-12 | 2020-10-12 | |
| US63/090,547 | 2020-10-12 | ||
| PCT/US2020/067463 WO2021138419A1 (en) | 2019-12-31 | 2020-12-30 | Compounds and compositions for treating conditions associated with sting activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023509421A JP2023509421A (ja) | 2023-03-08 |
| JP2023509421A5 true JP2023509421A5 (https=) | 2025-06-25 |
Family
ID=74550729
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022540327A Revoked JP2023509421A (ja) | 2019-12-31 | 2020-12-30 | Ｓｔｉｎｇ活性に関連する状態を治療するための化合物および組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230115274A1 (https=) |
| EP (1) | EP4085061A1 (https=) |
| JP (1) | JP2023509421A (https=) |
| CN (1) | CN115279770A (https=) |
| PY (1) | PY2089151A (https=) |
| TW (1) | TW202136255A (https=) |
| UY (1) | UY39005A (https=) |
| WO (1) | WO2021138419A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120004785A (zh) | 2018-07-03 | 2025-05-16 | 诺华制药股份有限公司 | 用于治疗与sting活性有关的疾病的化合物和组合物 |
| JP2024500874A (ja) | 2020-12-22 | 2024-01-10 | アイエフエム デュー インコーポレイテッド | がんを処置する方法 |
| US20240060982A1 (en) | 2020-12-22 | 2024-02-22 | Ifm Due, Inc. | Methods of treating cancer |
| EP4267129A1 (en) | 2020-12-22 | 2023-11-01 | IFM Due, Inc. | Methods of treating cancer |
| EP4267128A1 (en) | 2020-12-22 | 2023-11-01 | IFM Due, Inc. | Methods of treating cancer |
| JP2024502470A (ja) * | 2021-01-08 | 2024-01-19 | アイエフエム デュー インコーポレイテッド | Ｓｔｉｎｇ活性に関連する状態を治療するための化合物および組成物 |
| EP4274824A1 (en) | 2021-01-08 | 2023-11-15 | IFM Due, Inc. | Heterobicyclic compounds having an urea or analogue and their compositions for treating conditions associated with sting activity |
| IL310724A (en) | 2021-08-10 | 2024-04-01 | Ifm Due Inc | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH STING ACTIVITY |
| CN119677718A (zh) * | 2022-08-11 | 2025-03-21 | 杭州中美华东制药有限公司 | 具有sting抑制作用的酰胺类化合物及其药物组合物和用途 |
| WO2024064358A1 (en) | 2022-09-23 | 2024-03-28 | Ifm Due, Inc. | Compounds and compositions for treating conditions associated with sting activity |
| WO2024089155A1 (en) * | 2022-10-28 | 2024-05-02 | Boehringer Ingelheim International Gmbh | Heterocyclic compounds as sting antagonists |
| CN117756698A (zh) * | 2022-12-16 | 2024-03-26 | 中国药科大学 | 脲类化合物及其作为sting抑制剂的医药用途 |
| CN116023321B (zh) * | 2022-12-30 | 2024-11-29 | 中国药科大学 | Sting抑制剂前药及其医药用途 |
| WO2025228899A1 (en) | 2024-04-30 | 2025-11-06 | Boehringer Ingelheim International Gmbh | Further heterocyclic compounds as sting antagonists and the use thereof as medicament |
| US20250333414A1 (en) | 2024-04-30 | 2025-10-30 | Boehringer Ingelheim International Gmbh | Hetaryl substituted indazoles and benzimidazoles as sting antagonists and the use thereof as medicament |
| WO2025228900A1 (en) | 2024-04-30 | 2025-11-06 | Boehringer Ingelheim International Gmbh | Arylamide substituted indazoles and the use thereof as medicament |
| US20250333398A1 (en) | 2024-04-30 | 2025-10-30 | Boehringer Ingelheim International Gmbh | Monoaryl and hetaryl substituted indazoles and benzimidazoles as sting antagonists and the use thereof as medicament |
| WO2025228902A1 (en) | 2024-04-30 | 2025-11-06 | Boehringer Ingelheim International Gmbh | Heterocyclic acids as sting antagonists and the use thereof as medicament |
| WO2025228889A1 (en) | 2024-04-30 | 2025-11-06 | Boehringer Ingelheim International Gmbh | Monoarylic heterocyclic compounds as sting antagonists and the use thereof as medicament |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7927613B2 (en) | 2002-02-15 | 2011-04-19 | University Of South Florida | Pharmaceutical co-crystal compositions |
| EP1847541A4 (en) * | 2005-02-03 | 2009-12-30 | Takeda Pharmaceutical | CONDENSED PYRIMIDINE DERIVATIVE AND USE THEREOF |
| JP2013545740A (ja) * | 2010-11-10 | 2013-12-26 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | バニロイド受容体リガンドとしての置換された複素芳香族カルボキサミド誘導体および尿素誘導体 |
| US8497285B2 (en) | 2010-12-03 | 2013-07-30 | The Trustees Of The University Of Pennsylvania | Therapy of autoimmune colitis using a TIP60 inhibitor |
| FR2970967B1 (fr) * | 2011-01-27 | 2013-02-15 | Pf Medicament | Derives de type azaindazole ou diazaindazole comme medicament |
| CA2927009C (en) | 2013-10-21 | 2019-04-23 | Drexel University | Use of sting agonists to treat chronic hepatitis b virus infection |
| EP3556362A1 (en) * | 2018-04-16 | 2019-10-23 | Ecole Polytechnique Federale De Lausanne (Epfl) | Sting inhibitors |
| CN120004785A (zh) | 2018-07-03 | 2025-05-16 | 诺华制药股份有限公司 | 用于治疗与sting活性有关的疾病的化合物和组合物 |
-
2020
- 2020-12-30 JP JP2022540327A patent/JP2023509421A/ja not_active Revoked
- 2020-12-30 PY PY202002089151A patent/PY2089151A/es unknown
- 2020-12-30 WO PCT/US2020/067463 patent/WO2021138419A1/en not_active Ceased
- 2020-12-30 US US17/789,623 patent/US20230115274A1/en active Pending
- 2020-12-30 TW TW109146786A patent/TW202136255A/zh unknown
- 2020-12-30 CN CN202080097812.6A patent/CN115279770A/zh active Pending
- 2020-12-30 UY UY0001039005A patent/UY39005A/es unknown
- 2020-12-30 EP EP20849007.8A patent/EP4085061A1/en active Pending
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