JP2023508938A5 - - Google Patents
Info
- Publication number
- JP2023508938A5 JP2023508938A5 JP2022538731A JP2022538731A JP2023508938A5 JP 2023508938 A5 JP2023508938 A5 JP 2023508938A5 JP 2022538731 A JP2022538731 A JP 2022538731A JP 2022538731 A JP2022538731 A JP 2022538731A JP 2023508938 A5 JP2023508938 A5 JP 2023508938A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025136672A JP2025186252A (ja) | 2019-12-26 | 2025-08-20 | 抗ｃｄ３８治療剤と組み合わせたジヒドロオロト酸デヒドロゲナーゼの阻害のための方法および組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962953860P | 2019-12-26 | 2019-12-26 | |
| US62/953,860 | 2019-12-26 | ||
| PCT/US2020/067074 WO2021134045A1 (en) | 2019-12-26 | 2020-12-26 | Methods and compositions for inhibition of dihydroorotate dehydrogenase in combination with an anti-cd38 therapeutic agent |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025136672A Division JP2025186252A (ja) | 2019-12-26 | 2025-08-20 | 抗ｃｄ３８治療剤と組み合わせたジヒドロオロト酸デヒドロゲナーゼの阻害のための方法および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023508938A JP2023508938A (ja) | 2023-03-06 |
| JP2023508938A5 true JP2023508938A5 (enExample) | 2024-01-25 |
| JP7736275B2 JP7736275B2 (ja) | 2025-09-09 |
Family
ID=76575158
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022538731A Active JP7736275B2 (ja) | 2019-12-26 | 2020-12-26 | 抗ｃｄ３８治療剤と組み合わせたジヒドロオロト酸デヒドロゲナーゼの阻害のための方法および組成物 |
| JP2025136672A Pending JP2025186252A (ja) | 2019-12-26 | 2025-08-20 | 抗ｃｄ３８治療剤と組み合わせたジヒドロオロト酸デヒドロゲナーゼの阻害のための方法および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025136672A Pending JP2025186252A (ja) | 2019-12-26 | 2025-08-20 | 抗ｃｄ３８治療剤と組み合わせたジヒドロオロト酸デヒドロゲナーゼの阻害のための方法および組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230303710A1 (enExample) |
| EP (1) | EP4081219A4 (enExample) |
| JP (2) | JP7736275B2 (enExample) |
| KR (1) | KR20220133198A (enExample) |
| CN (1) | CN115335052A (enExample) |
| AU (1) | AU2020412805A1 (enExample) |
| CA (1) | CA3165475A1 (enExample) |
| WO (1) | WO2021134045A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021134042A1 (en) * | 2019-12-26 | 2021-07-01 | Ohio State Innovation Foundation | Methods and compositions for inhibition of dihydroorotate dehydrogenase |
| CN117915938A (zh) * | 2021-06-30 | 2024-04-19 | 俄亥俄州国家创新基金会 | 用于与抗cd47-sirpα治疗剂组合抑制二氢乳清酸脱氢酶的方法和组合物 |
| EP4436579A4 (en) * | 2021-11-22 | 2025-10-22 | Ohio State Innovation Foundation | METHODS AND COMPOSITIONS FOR TARGETING ALTERNATIVE METABOLISM IN CONJUNCTION WITH FLT3 INHIBITOR-MEDIATED ANTILEUKEMIA ACTIONS |
| WO2025202415A1 (en) * | 2024-03-28 | 2025-10-02 | Institut National de la Santé et de la Recherche Médicale | Dhodh inhibitors for use in the chronopharmacoligical treatment and prevention of obesity and obesity-related metabolic disorders |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7405237B2 (en) * | 2004-07-28 | 2008-07-29 | Celgene Corporation | Isoindoline compounds and methods of their use |
| JP5225069B2 (ja) * | 2005-03-23 | 2013-07-03 | ゲンマブ エー／エス | 多発性骨髄腫の治療のためのｃｄ３８に対する抗体 |
| BR112012031727B1 (pt) * | 2010-06-15 | 2022-03-29 | Genmab A/S | Conjugado de droga-anticorpo, composição farmacêutica, e, uso do conjugado de droga- anticorpo |
| US11096934B2 (en) * | 2015-09-01 | 2021-08-24 | The Broad Institute, Inc. | Compounds and methods useful for treating or preventing hematological cancers |
| JP6961879B2 (ja) * | 2015-12-30 | 2021-11-05 | レ ラボラトワール セルヴィエ ソシエテ・パール・アクシオンス・サンプリフィエ | 変異体イソクエン酸デヒドロゲナーゼを包含する腫瘍の処置 |
| WO2018015498A1 (en) * | 2016-07-20 | 2018-01-25 | Hybrigenics Sa | Combinations of inecalcitol with an anti-cd38 agent and their uses for treating cancer |
| US20200121815A1 (en) | 2017-07-31 | 2020-04-23 | Actinium Pharmaceuticals, Inc. | Treatments for a hematological malignancy |
| WO2019246603A1 (en) * | 2018-06-22 | 2019-12-26 | Ohio State Innovation Foundation | Methods and compositions for inhibition of dihydroorotate dehydrogenase |
| US20230089524A1 (en) * | 2019-12-26 | 2023-03-23 | Ohio State Innovation Foundation | Compositions for use in the inhibition of dihydroorotate dehydrogenase |
| WO2021134042A1 (en) * | 2019-12-26 | 2021-07-01 | Ohio State Innovation Foundation | Methods and compositions for inhibition of dihydroorotate dehydrogenase |
| US20230109418A1 (en) * | 2019-12-26 | 2023-04-06 | Ohio State Innovation Foundation | Compositions for use for the inhibition of dihydroorotate dehydrogenase |
-
2020
- 2020-12-26 AU AU2020412805A patent/AU2020412805A1/en active Pending
- 2020-12-26 KR KR1020227025804A patent/KR20220133198A/ko active Pending
- 2020-12-26 US US17/789,187 patent/US20230303710A1/en active Pending
- 2020-12-26 WO PCT/US2020/067074 patent/WO2021134045A1/en not_active Ceased
- 2020-12-26 CA CA3165475A patent/CA3165475A1/en active Pending
- 2020-12-26 EP EP20905006.1A patent/EP4081219A4/en active Pending
- 2020-12-26 CN CN202080095284.0A patent/CN115335052A/zh active Pending
- 2020-12-26 JP JP2022538731A patent/JP7736275B2/ja active Active
-
2025
- 2025-08-20 JP JP2025136672A patent/JP2025186252A/ja active Pending