JP2023508327A5 - - Google Patents

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Publication number
JP2023508327A5
JP2023508327A5 JP2022538216A JP2022538216A JP2023508327A5 JP 2023508327 A5 JP2023508327 A5 JP 2023508327A5 JP 2022538216 A JP2022538216 A JP 2022538216A JP 2022538216 A JP2022538216 A JP 2022538216A JP 2023508327 A5 JP2023508327 A5 JP 2023508327A5
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JP
Japan
Prior art keywords
cancer
unsubstituted
substituted
product according
pharmaceutical product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022538216A
Other languages
English (en)
Japanese (ja)
Other versions
JP7794448B2 (ja
JP2023508327A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/065401 external-priority patent/WO2021127039A1/en
Publication of JP2023508327A publication Critical patent/JP2023508327A/ja
Publication of JP2023508327A5 publication Critical patent/JP2023508327A5/ja
Application granted granted Critical
Publication of JP7794448B2 publication Critical patent/JP7794448B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2022538216A 2019-12-20 2020-12-16 組み合わせ Active JP7794448B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962951991P 2019-12-20 2019-12-20
US62/951,991 2019-12-20
PCT/US2020/065401 WO2021127039A1 (en) 2019-12-20 2020-12-16 Combinations

Publications (3)

Publication Number Publication Date
JP2023508327A JP2023508327A (ja) 2023-03-02
JP2023508327A5 true JP2023508327A5 (enExample) 2023-12-25
JP7794448B2 JP7794448B2 (ja) 2026-01-06

Family

ID=76478158

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022538216A Active JP7794448B2 (ja) 2019-12-20 2020-12-16 組み合わせ

Country Status (12)

Country Link
US (1) US20230068370A1 (enExample)
EP (1) EP4069241A4 (enExample)
JP (1) JP7794448B2 (enExample)
KR (1) KR20220119658A (enExample)
CN (1) CN115087447A (enExample)
AU (1) AU2020407514A1 (enExample)
BR (1) BR112022012278A2 (enExample)
CA (1) CA3165350A1 (enExample)
IL (1) IL294074A (enExample)
MX (1) MX2022007629A (enExample)
TW (1) TWI895318B (enExample)
WO (1) WO2021127039A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020384291A1 (en) 2019-11-15 2022-05-26 Recurium Ip Holdings, Llc Chiral synthesis of a tertiary alcohol
WO2022011391A1 (en) 2020-07-09 2022-01-13 Recurium Ip Holdings, Llc Salts and forms of a wee1 inhibitor
CN116462687B (zh) * 2022-01-18 2025-01-07 江苏天士力帝益药业有限公司 Wee1抑制剂及其制备和用途
WO2023147297A2 (en) * 2022-01-25 2023-08-03 Verastem, Inc. Combination therapy for treating abnormal cell growth
TW202543650A (zh) 2024-03-08 2025-11-16 美商海爾達醫療運營公司 異雙官能化合物及其在治療疾病中之用途
WO2025193930A1 (en) * 2024-03-14 2025-09-18 Zeno Management, Inc. Wee1 inhibitor combination therapy

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015095250A1 (en) * 2013-12-20 2015-06-25 Merck Sharp & Dohme Corp. Combination cancer therapy of wee1 and mtor inhibitors
TWI874834B (zh) 2014-12-18 2025-03-01 瑞士商赫孚孟拉羅股份公司 四氫-吡啶并[3,4-b]吲哚雌激素受體調節劑及其用途
CN109843882A (zh) * 2016-06-16 2019-06-04 豪夫迈·罗氏有限公司 四氢-吡啶并[3,4-b]吲哚雌激素受体调节剂及其用途
EP3640251B1 (en) * 2016-10-24 2021-12-08 Astrazeneca AB 6,7,8,9-tetrahydro-3h-pyrazolo[4,3-f]isoquinoline derivatives useful in the treatment of cancer
CN109422754A (zh) * 2017-08-24 2019-03-05 上海迪诺医药科技有限公司 吡唑并[3,4-d]嘧啶-3-酮衍生物、其药物组合物及应用
WO2019165204A1 (en) * 2018-02-23 2019-08-29 Newave Pharmaceutical Inc. 1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidine-3-one compounds as inhibitors of wee-1 kinase
EP4566612A3 (en) * 2018-03-09 2025-08-20 Recurium IP Holdings, LLC Substituted 1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-ones

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