JP2023507033A5 - - Google Patents

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Publication number
JP2023507033A5
JP2023507033A5 JP2022538373A JP2022538373A JP2023507033A5 JP 2023507033 A5 JP2023507033 A5 JP 2023507033A5 JP 2022538373 A JP2022538373 A JP 2022538373A JP 2022538373 A JP2022538373 A JP 2022538373A JP 2023507033 A5 JP2023507033 A5 JP 2023507033A5
Authority
JP
Japan
Prior art keywords
mutations
domain
polypeptide
protein complex
numbering
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022538373A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023507033A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CA2020/051753 external-priority patent/WO2021119832A1/en
Publication of JP2023507033A publication Critical patent/JP2023507033A/ja
Publication of JP2023507033A5 publication Critical patent/JP2023507033A5/ja
Pending legal-status Critical Current

Links

JP2022538373A 2019-12-20 2020-12-18 ポリペプチド、タンパク質複合体及びそれを作製する方法 Pending JP2023507033A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962951701P 2019-12-20 2019-12-20
US62/951,701 2019-12-20
PCT/CA2020/051753 WO2021119832A1 (en) 2019-12-20 2020-12-18 Polypeptides, protein complexes and method for making same

Publications (2)

Publication Number Publication Date
JP2023507033A JP2023507033A (ja) 2023-02-20
JP2023507033A5 true JP2023507033A5 (enExample) 2023-12-27

Family

ID=76476896

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022538373A Pending JP2023507033A (ja) 2019-12-20 2020-12-18 ポリペプチド、タンパク質複合体及びそれを作製する方法

Country Status (8)

Country Link
US (1) US20230242676A1 (enExample)
EP (1) EP4077374A4 (enExample)
JP (1) JP2023507033A (enExample)
CN (1) CN115003693A (enExample)
AR (1) AR120870A1 (enExample)
CA (1) CA3171363A1 (enExample)
TW (1) TWI907375B (enExample)
WO (1) WO2021119832A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3231417A1 (en) * 2021-09-10 2023-03-16 Jian Shi Anti-ang2 antibody, preparation method therefor, and application thereof
EP4408893A4 (en) 2021-09-29 2026-02-18 Kisoji Biotechnology Inc Binding agents targeting tumor cells expressing too much 2
TWI876227B (zh) * 2021-11-17 2025-03-11 大陸商南京再明醫藥有限公司 多特異性抗體及其藥物用途
EP4599066A1 (en) * 2022-10-03 2025-08-13 Kisoji Biotechnology Inc. Multispecific binding agents targeting dopamine receptor d2 and methods of use thereof
EP4608867A1 (en) * 2022-10-25 2025-09-03 Kisoji Biotechnology Inc. Binding agents targeting cd36-expressing tumor cells
PE20252392A1 (es) 2022-12-12 2025-10-10 Lanova Medicines Ltd Anticuerpos biespecificos que se dirigen a pd1 y vegf
CN121419995A (zh) * 2023-04-04 2026-01-27 加拿大商木曾路生物科技公司 靶向表达trop2的肿瘤细胞的结合剂
EP4520768A1 (en) 2023-09-06 2025-03-12 BioNTech SE Vhh-ch3 fusion proteins

Family Cites Families (13)

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Publication number Priority date Publication date Assignee Title
WO2013012733A1 (en) * 2011-07-15 2013-01-24 Biogen Idec Ma Inc. Heterodimeric fc regions, binding molecules comprising same, and methods relating thereto
RS60499B1 (sr) * 2011-12-20 2020-08-31 Medimmune Llc Modifikovani polipeptidi za bispecifične skelete antitela
US20160257748A1 (en) * 2013-09-25 2016-09-08 Amgen Inc. V-c-fc-v-c antibody
MX380658B (es) * 2014-01-15 2025-03-11 Hoffmann La Roche Variantes de region fc con union mejorada de la proteina a.
EP4299595A3 (en) * 2014-05-02 2024-03-13 Momenta Pharmaceuticals, Inc. Compositions and methods related to engineered fc constructs
ES2846881T3 (es) * 2015-05-01 2021-07-30 Inhibrx Inc Moléculas que se dirigen al sistema de secreción de tipo III
WO2016192613A1 (zh) * 2015-06-01 2016-12-08 中山大学 具有融合至常规Fab片段的单域抗原结合片段的二价抗体
KR20180098671A (ko) * 2016-01-11 2018-09-04 인히브릭스, 인크. 다가 및 다중특이적 ox40-결합 융합 단백질
KR20180096789A (ko) * 2016-01-11 2018-08-29 인히브릭스, 인크. 다가 및 다중특이적 41bb-결합 융합 단백질
CN110177805B (zh) * 2016-10-19 2024-04-02 英温拉公司 抗体构建体
JP7543134B2 (ja) * 2017-10-03 2024-09-02 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング システイン操作された抗原結合分子
KR20200118423A (ko) * 2018-01-08 2020-10-15 난징 레전드 바이오테크 씨오., 엘티디. 다중특이성 항원 결합 단백질 및 이의 사용 방법
SG11202008474QA (en) * 2018-03-27 2020-10-29 Systimmune Inc Guidance and navigation control proteins and method of making and using thereof

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