JP2023506118A - 皮膚エリテマトーデス及び扁平苔癬(lp)の治療のためのjak1阻害剤の使用 - Google Patents
皮膚エリテマトーデス及び扁平苔癬(lp)の治療のためのjak1阻害剤の使用 Download PDFInfo
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- JP2023506118A JP2023506118A JP2022523053A JP2022523053A JP2023506118A JP 2023506118 A JP2023506118 A JP 2023506118A JP 2022523053 A JP2022523053 A JP 2022523053A JP 2022523053 A JP2022523053 A JP 2022523053A JP 2023506118 A JP2023506118 A JP 2023506118A
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- pyrrolo
- pyrimidin
- jak1
- pyrazol
- acetonitrile
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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PCT/US2019/056533 WO2021076124A1 (fr) | 2019-10-16 | 2019-10-16 | Utilisation d'inhibiteurs de jak1 pour le traitement du lupus érythémateux cutané et du lichen plan (l.p.) |
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EP4221711A1 (fr) * | 2020-10-02 | 2023-08-09 | Incyte Corporation | Ruxolitinib topique pour le traitement de lichen plan |
CA3219092A1 (fr) * | 2021-05-03 | 2022-11-10 | Incyte Corporation | Inhibiteurs de la voie jak1 pour le traitement du prurigo nodulaire |
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