JP2023503722A5 - - Google Patents
Info
- Publication number
- JP2023503722A5 JP2023503722A5 JP2022556456A JP2022556456A JP2023503722A5 JP 2023503722 A5 JP2023503722 A5 JP 2023503722A5 JP 2022556456 A JP2022556456 A JP 2022556456A JP 2022556456 A JP2022556456 A JP 2022556456A JP 2023503722 A5 JP2023503722 A5 JP 2023503722A5
- Authority
- JP
- Japan
- Prior art keywords
- unsubstituted
- independently
- substituted
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962940835P | 2019-11-26 | 2019-11-26 | |
| US62/940,835 | 2019-11-26 | ||
| PCT/US2020/062358 WO2021108662A1 (en) | 2019-11-26 | 2020-11-25 | Compound comprising a nucleic acid and a half-life extension motif |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023503722A JP2023503722A (ja) | 2023-01-31 |
| JP2023503722A5 true JP2023503722A5 (https=) | 2023-12-04 |
| JP7821737B2 JP7821737B2 (ja) | 2026-02-27 |
Family
ID=74046141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022556456A Active JP7821737B2 (ja) | 2019-11-26 | 2020-11-25 | 核酸および半減期モチーフを含む化合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230158150A1 (https=) |
| EP (1) | EP4065172A1 (https=) |
| JP (1) | JP7821737B2 (https=) |
| KR (1) | KR20220150881A (https=) |
| CN (1) | CN115397471B (https=) |
| AU (1) | AU2020391218A1 (https=) |
| BR (1) | BR112022009976A2 (https=) |
| CA (1) | CA3161669A1 (https=) |
| IL (1) | IL293341B1 (https=) |
| MX (1) | MX2022006097A (https=) |
| WO (1) | WO2021108662A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023039522A1 (en) * | 2021-09-10 | 2023-03-16 | Guardian Therapeutics, Llc | Fatty acid conjugates of nucleic acids |
| EP4522742A2 (en) | 2022-05-13 | 2025-03-19 | Alnylam Pharmaceuticals, Inc. | Single-stranded loop oligonucleotides |
| EP4709855A2 (en) | 2023-05-12 | 2026-03-18 | Alnylam Pharmaceuticals, Inc. | Single-stranded loop oligonucleotides |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2586704B1 (fr) * | 1985-09-04 | 1987-12-18 | Centre Nat Rech Scient | Nouveaux composes comportant une sequence d'oligonucleotide liee a un agent d'intercalation et a un groupe chimique activable, leur synthese et leurs applications a titre de nucleases artificielles specifiques de sequences. centre national de la recherche scientifique (cnrs) |
| US4783443A (en) | 1986-03-03 | 1988-11-08 | The University Of Chicago | Amino acyl cephalosporin derivatives |
| WO2015006740A2 (en) * | 2013-07-11 | 2015-01-15 | Alnylam Pharmaceuticals, Inc. | Oligonucleotide-ligand conjugates and process for their preparation |
| US10588980B2 (en) * | 2014-06-23 | 2020-03-17 | Novartis Ag | Fatty acids and their use in conjugation to biomolecules |
| EP3603648B1 (en) * | 2017-03-29 | 2025-09-17 | Shionogi & Co., Ltd | Complex of nucleic acid medicine and multibranched lipid |
| CN120247995A (zh) * | 2018-05-30 | 2025-07-04 | 诺华股份有限公司 | 脂质修饰的核酸化合物和方法 |
-
2020
- 2020-11-24 IL IL293341A patent/IL293341B1/en unknown
- 2020-11-25 MX MX2022006097A patent/MX2022006097A/es unknown
- 2020-11-25 CN CN202080094151.1A patent/CN115397471B/zh active Active
- 2020-11-25 KR KR1020227021677A patent/KR20220150881A/ko active Pending
- 2020-11-25 WO PCT/US2020/062358 patent/WO2021108662A1/en not_active Ceased
- 2020-11-25 EP EP20829416.5A patent/EP4065172A1/en active Pending
- 2020-11-25 AU AU2020391218A patent/AU2020391218A1/en active Pending
- 2020-11-25 BR BR112022009976A patent/BR112022009976A2/pt unknown
- 2020-11-25 CA CA3161669A patent/CA3161669A1/en active Pending
- 2020-11-25 JP JP2022556456A patent/JP7821737B2/ja active Active
- 2020-11-25 US US17/778,372 patent/US20230158150A1/en active Pending
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