JP2023503472A5 - - Google Patents
Info
- Publication number
- JP2023503472A5 JP2023503472A5 JP2022530716A JP2022530716A JP2023503472A5 JP 2023503472 A5 JP2023503472 A5 JP 2023503472A5 JP 2022530716 A JP2022530716 A JP 2022530716A JP 2022530716 A JP2022530716 A JP 2022530716A JP 2023503472 A5 JP2023503472 A5 JP 2023503472A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- seq
- gdf15
- acid sequence
- variant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2019-0153680 | 2019-11-26 | ||
| KR20190153680 | 2019-11-26 | ||
| PCT/KR2020/016842 WO2021107603A2 (en) | 2019-11-26 | 2020-11-25 | Long-acting gdf15 fusion protein and pharmaceutical composition comprising same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023503472A JP2023503472A (ja) | 2023-01-30 |
| JP2023503472A5 true JP2023503472A5 (https=) | 2023-12-04 |
Family
ID=76130664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022530716A Pending JP2023503472A (ja) | 2019-11-26 | 2020-11-25 | 長時間作用型ｇｄｆ１５融合タンパク質およびそれを含む医薬組成物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230002460A1 (https=) |
| EP (1) | EP4065597A4 (https=) |
| JP (1) | JP2023503472A (https=) |
| KR (1) | KR20210065057A (https=) |
| CN (1) | CN114729020A (https=) |
| AU (1) | AU2020394255A1 (https=) |
| BR (1) | BR112022010227A2 (https=) |
| CA (1) | CA3161302A1 (https=) |
| MX (1) | MX2022006173A (https=) |
| WO (1) | WO2021107603A2 (https=) |
| ZA (1) | ZA202204624B (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117750968A (zh) * | 2021-05-21 | 2024-03-22 | 株式会社柳韩洋行 | 用于预防或治疗非酒精性脂肪性肝病或非酒精性脂肪性肝炎的包括生长分化因子-15变体的组合物 |
| CA3219645A1 (en) * | 2021-05-21 | 2022-11-24 | Yuhan Corporation | Composition for combination therapy comprising growth differentiation factor-15 variant and glucagon-like peptide-1 receptor agonist |
| US20240391971A1 (en) * | 2021-08-24 | 2024-11-28 | Sunshine Lake Pharma Co., Ltd. | Gdf15 fusion proteins and uses thereof |
| CN120530128A (zh) * | 2022-11-18 | 2025-08-22 | 株式会社柳韩洋行 | 双功能蛋白及其用途 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5288931A (en) * | 1991-12-06 | 1994-02-22 | Genentech, Inc. | Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation |
| GB9912350D0 (en) * | 1999-05-26 | 1999-07-28 | European Molecular Biology Lab Embl | Modified cytokine |
| FI117667B (fi) * | 2001-07-05 | 2007-01-15 | Univ Zuerich | Farmaseuttinen koostumus, joka soveltuu käytettäväksi ortopediassa ja hammaslääketieteessä |
| EP2441466B1 (en) | 2004-04-13 | 2014-07-23 | St Vincent's Hospital Sydney Limited | MIC-1 inhibiting agent |
| AU2012212047A1 (en) * | 2011-02-03 | 2013-08-22 | Xoma Technology Ltd. | Methods and materials for enhancing functional protein expression in bacteria |
| EP3683228A3 (en) * | 2012-01-26 | 2020-07-29 | Amgen Inc. | Growth differentiation factor 15 (gdf-15) polypeptides |
| US9161966B2 (en) * | 2013-01-30 | 2015-10-20 | Ngm Biopharmaceuticals, Inc. | GDF15 mutein polypeptides |
| KR101993714B1 (ko) * | 2013-01-30 | 2019-06-28 | 엔지엠 바이오파마슈티컬스, 아이엔씨. | 대사 장애를 치료하는데 이용하기 위한 조성물과 방법 |
| US9862752B2 (en) * | 2013-07-31 | 2018-01-09 | Amgen Inc. | Growth differentiation factor 15 (GDF-15) constructs |
| RU2017101436A (ru) * | 2014-06-24 | 2018-07-24 | Ново Нордиск А/С | Mic-1 слитные белки и их применение |
| AU2015296640B2 (en) * | 2014-07-30 | 2020-05-21 | Ngm Biopharmaceuticals, Inc. | Compositions and methods of use for treating metabolic disorders |
| US10603359B2 (en) * | 2014-10-30 | 2020-03-31 | Acceleron Pharma Inc. | Methods and compositions using GDF15 polypeptides for increasing red blood cells |
| EP3701969A1 (en) * | 2014-10-31 | 2020-09-02 | NGM Biopharmaceuticals, Inc. | Compositions and methods of use for treating metabolic disorders |
| US10336812B2 (en) * | 2016-05-10 | 2019-07-02 | Janssen Biotech, Inc. | GDF15 fusion proteins and uses thereof |
| KR101727506B1 (ko) * | 2016-07-14 | 2017-05-04 | 충남대학교 산학협력단 | Gdf15 단백질 또는 이를 암호화하는 폴리뉴클레오티드를 유효성분으로 함유하는 지방간의 예방 또는 치료용 약학적 조성물 |
-
2020
- 2020-11-25 CA CA3161302A patent/CA3161302A1/en active Pending
- 2020-11-25 BR BR112022010227A patent/BR112022010227A2/pt unknown
- 2020-11-25 JP JP2022530716A patent/JP2023503472A/ja active Pending
- 2020-11-25 CN CN202080081137.8A patent/CN114729020A/zh active Pending
- 2020-11-25 US US17/779,932 patent/US20230002460A1/en active Pending
- 2020-11-25 MX MX2022006173A patent/MX2022006173A/es unknown
- 2020-11-25 KR KR1020200160013A patent/KR20210065057A/ko active Pending
- 2020-11-25 AU AU2020394255A patent/AU2020394255A1/en active Pending
- 2020-11-25 EP EP20892374.8A patent/EP4065597A4/en active Pending
- 2020-11-25 WO PCT/KR2020/016842 patent/WO2021107603A2/en not_active Ceased
-
2022
- 2022-04-25 ZA ZA2022/04624A patent/ZA202204624B/en unknown
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