JP2023502752A5 - - Google Patents
Info
- Publication number
- JP2023502752A5 JP2023502752A5 JP2022529847A JP2022529847A JP2023502752A5 JP 2023502752 A5 JP2023502752 A5 JP 2023502752A5 JP 2022529847 A JP2022529847 A JP 2022529847A JP 2022529847 A JP2022529847 A JP 2022529847A JP 2023502752 A5 JP2023502752 A5 JP 2023502752A5
- Authority
- JP
- Japan
- Prior art keywords
- subset
- nucleic acid
- carrier nucleic
- acid molecule
- methylated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025207226A JP2026035733A (ja) | 2019-11-26 | 2025-11-27 | メチル化ポリヌクレオチドの結合を改善するための方法、組成物およびシステム |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962940853P | 2019-11-26 | 2019-11-26 | |
| US62/940,853 | 2019-11-26 | ||
| PCT/US2020/062419 WO2021108708A1 (en) | 2019-11-26 | 2020-11-25 | Methods, compositions and systems for improving the binding of methylated polynucleotides |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025207226A Division JP2026035733A (ja) | 2019-11-26 | 2025-11-27 | メチル化ポリヌクレオチドの結合を改善するための方法、組成物およびシステム |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023502752A JP2023502752A (ja) | 2023-01-25 |
| JP2023502752A5 true JP2023502752A5 (https=) | 2023-12-05 |
| JP7783176B2 JP7783176B2 (ja) | 2025-12-09 |
Family
ID=73855566
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022529847A Active JP7783176B2 (ja) | 2019-11-26 | 2020-11-25 | メチル化ポリヌクレオチドの結合を改善するための方法、組成物およびシステム |
| JP2025207226A Pending JP2026035733A (ja) | 2019-11-26 | 2025-11-27 | メチル化ポリヌクレオチドの結合を改善するための方法、組成物およびシステム |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025207226A Pending JP2026035733A (ja) | 2019-11-26 | 2025-11-27 | メチル化ポリヌクレオチドの結合を改善するための方法、組成物およびシステム |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20210214800A1 (https=) |
| EP (2) | EP4617375A3 (https=) |
| JP (2) | JP7783176B2 (https=) |
| CN (1) | CN114746560A (https=) |
| CA (1) | CA3157560A1 (https=) |
| ES (1) | ES3031713T3 (https=) |
| WO (1) | WO2021108708A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020160414A1 (en) * | 2019-01-31 | 2020-08-06 | Guardant Health, Inc. | Compositions and methods for isolating cell-free dna |
| WO2023107709A1 (en) * | 2021-12-10 | 2023-06-15 | Adela, Inc. | Methods and systems for generating sequencing libraries |
| WO2026060266A1 (en) * | 2024-09-13 | 2026-03-19 | Guardant Health, Inc. | Use of copy number variants for the identification of false positive tumor calls |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6582908B2 (en) | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
| US20030017081A1 (en) | 1994-02-10 | 2003-01-23 | Affymetrix, Inc. | Method and apparatus for imaging a sample on a device |
| DE69528706T2 (de) | 1994-08-19 | 2003-06-12 | Pe Corp. (Ny), Foster City | Gekoppeltes ampflikation- und ligationverfahren |
| GB9620209D0 (en) | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
| GB9626815D0 (en) | 1996-12-23 | 1997-02-12 | Cemu Bioteknik Ab | Method of sequencing DNA |
| US6969488B2 (en) | 1998-05-22 | 2005-11-29 | Solexa, Inc. | System and apparatus for sequential processing of analytes |
| AR021833A1 (es) | 1998-09-30 | 2002-08-07 | Applied Research Systems | Metodos de amplificacion y secuenciacion de acido nucleico |
| US6818395B1 (en) | 1999-06-28 | 2004-11-16 | California Institute Of Technology | Methods and apparatus for analyzing polynucleotide sequences |
| US7501245B2 (en) | 1999-06-28 | 2009-03-10 | Helicos Biosciences Corp. | Methods and apparatuses for analyzing polynucleotide sequences |
| AU7537200A (en) | 1999-09-29 | 2001-04-30 | Solexa Ltd. | Polynucleotide sequencing |
| ATE377093T1 (de) | 2000-07-07 | 2007-11-15 | Visigen Biotechnologies Inc | Sequenzbestimmung in echtzeit |
| WO2003046146A2 (en) | 2001-11-28 | 2003-06-05 | Applera Corporation | Compositions and methods of selective nucleic acid isolation |
| US7169560B2 (en) | 2003-11-12 | 2007-01-30 | Helicos Biosciences Corporation | Short cycle methods for sequencing polynucleotides |
| CA2579150C (en) | 2004-09-17 | 2014-11-25 | Pacific Biosciences Of California, Inc. | Apparatus and method for analysis of molecules |
| US7170050B2 (en) | 2004-09-17 | 2007-01-30 | Pacific Biosciences Of California, Inc. | Apparatus and methods for optical analysis of molecules |
| JP5149013B2 (ja) * | 2004-11-29 | 2013-02-20 | セクエノム，インコーポレイティド | メチル化ｄｎａを検出する手段、及び方法 |
| US7482120B2 (en) | 2005-01-28 | 2009-01-27 | Helicos Biosciences Corporation | Methods and compositions for improving fidelity in a nucleic acid synthesis reaction |
| US7282337B1 (en) | 2006-04-14 | 2007-10-16 | Helicos Biosciences Corporation | Methods for increasing accuracy of nucleic acid sequencing |
| US20080102452A1 (en) * | 2006-10-31 | 2008-05-01 | Roberts Douglas N | Control nucleic acid constructs for use in analysis of methylation status |
| US20120252015A1 (en) * | 2011-02-18 | 2012-10-04 | Bio-Rad Laboratories | Methods and compositions for detecting genetic material |
| US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| US20140093873A1 (en) * | 2012-07-13 | 2014-04-03 | Sequenom, Inc. | Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
| US20150005199A1 (en) * | 2012-08-14 | 2015-01-01 | 10X Technologies, Inc. | Compositions and methods for sample processing |
| CN104781421B (zh) | 2012-09-04 | 2020-06-05 | 夸登特健康公司 | 检测稀有突变和拷贝数变异的系统和方法 |
| US20160040229A1 (en) | 2013-08-16 | 2016-02-11 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| DE102012219142B4 (de) * | 2012-10-19 | 2016-02-25 | Analytik Jena Ag | Verfahren zum Trennen, Erfassen oder Anreichern von unterschiedlichen DNA-Spezies |
| US10087481B2 (en) * | 2013-03-19 | 2018-10-02 | New England Biolabs, Inc. | Enrichment of target sequences |
| EP4358097A1 (en) | 2014-07-25 | 2024-04-24 | University of Washington | Methods of determining tissues and/or cell types giving rise to cell-free dna, and methods of identifying a disease or disorder using same |
| KR102522067B1 (ko) * | 2016-05-03 | 2023-04-13 | 유니버시티 헬스 네트워크 | 무-세포 메틸화된 dna의 포획 방법 및 이의 이용 |
| WO2018009723A1 (en) | 2016-07-06 | 2018-01-11 | Guardant Health, Inc. | Methods for fragmentome profiling of cell-free nucleic acids |
| MX2019007444A (es) * | 2016-12-22 | 2019-08-16 | Guardant Health Inc | Metodos y sistemas para analisis de moleculas de acido nucleico. |
| CA3055817A1 (en) * | 2017-03-08 | 2018-09-13 | President And Fellows Of Harvard College | Methods of amplifying dna to maintain methylation status |
| JP2020527340A (ja) * | 2017-06-30 | 2020-09-10 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | セルフリーｄｎａ中のｄｎａメチル化を評価するための方法およびシステム |
| BR112020000681A2 (pt) * | 2017-07-12 | 2020-07-14 | University Health Network | detecção e classificação de cancro utilizando análise de metilome |
| CN107475409A (zh) * | 2017-09-19 | 2017-12-15 | 上海兰卫医学检验所股份有限公司 | 一种提高液体样品核酸检测灵敏度的样品预处理方法 |
| CA3276585A1 (en) * | 2017-12-11 | 2026-03-02 | Umc Utrecht Holding B.V. | Methods for preparing nucleic acid molecules for sequencing |
-
2020
- 2020-11-25 EP EP25177558.1A patent/EP4617375A3/en active Pending
- 2020-11-25 ES ES20828204T patent/ES3031713T3/es active Active
- 2020-11-25 US US17/105,407 patent/US20210214800A1/en active Pending
- 2020-11-25 CA CA3157560A patent/CA3157560A1/en active Pending
- 2020-11-25 CN CN202080082559.7A patent/CN114746560A/zh active Pending
- 2020-11-25 WO PCT/US2020/062419 patent/WO2021108708A1/en not_active Ceased
- 2020-11-25 JP JP2022529847A patent/JP7783176B2/ja active Active
- 2020-11-25 EP EP20828204.6A patent/EP4065725B1/en active Active
-
2025
- 2025-11-27 JP JP2025207226A patent/JP2026035733A/ja active Pending
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