JP2023502473A5 - - Google Patents

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Publication number
JP2023502473A5
JP2023502473A5 JP2022529540A JP2022529540A JP2023502473A5 JP 2023502473 A5 JP2023502473 A5 JP 2023502473A5 JP 2022529540 A JP2022529540 A JP 2022529540A JP 2022529540 A JP2022529540 A JP 2022529540A JP 2023502473 A5 JP2023502473 A5 JP 2023502473A5
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JP
Japan
Prior art keywords
sequence
parapalindromic
recombinase polypeptide
sequences
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022529540A
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English (en)
Japanese (ja)
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JP2023502473A (ja
JP7762148B2 (ja
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Priority claimed from PCT/US2020/061705 external-priority patent/WO2021102390A1/en
Publication of JP2023502473A publication Critical patent/JP2023502473A/ja
Publication of JP2023502473A5 publication Critical patent/JP2023502473A5/ja
Priority to JP2025175403A priority Critical patent/JP2026012799A/ja
Application granted granted Critical
Publication of JP7762148B2 publication Critical patent/JP7762148B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2022529540A 2019-11-22 2020-11-22 リコンビナーゼ組成物及び使用方法 Active JP7762148B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025175403A JP2026012799A (ja) 2019-11-22 2025-10-17 リコンビナーゼ組成物及び使用方法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962939525P 2019-11-22 2019-11-22
US62/939,525 2019-11-22
US202063039309P 2020-06-15 2020-06-15
US63/039,309 2020-06-15
US202063068402P 2020-08-21 2020-08-21
US63/068,402 2020-08-21
PCT/US2020/061705 WO2021102390A1 (en) 2019-11-22 2020-11-22 Recombinase compositions and methods of use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025175403A Division JP2026012799A (ja) 2019-11-22 2025-10-17 リコンビナーゼ組成物及び使用方法

Publications (3)

Publication Number Publication Date
JP2023502473A JP2023502473A (ja) 2023-01-24
JP2023502473A5 true JP2023502473A5 (https=) 2023-12-18
JP7762148B2 JP7762148B2 (ja) 2025-10-29

Family

ID=75980912

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022529540A Active JP7762148B2 (ja) 2019-11-22 2020-11-22 リコンビナーゼ組成物及び使用方法
JP2025175403A Pending JP2026012799A (ja) 2019-11-22 2025-10-17 リコンビナーゼ組成物及び使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025175403A Pending JP2026012799A (ja) 2019-11-22 2025-10-17 リコンビナーゼ組成物及び使用方法

Country Status (6)

Country Link
US (1) US20230131847A1 (https=)
EP (1) EP4061940A4 (https=)
JP (2) JP7762148B2 (https=)
CN (1) CN115397984A (https=)
CA (1) CA3162499A1 (https=)
WO (1) WO2021102390A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3844272A1 (en) 2018-08-28 2021-07-07 Flagship Pioneering Innovations VI, LLC Methods and compositions for modulating a genome
EP3847254A4 (en) 2018-09-07 2022-08-10 Beam Therapeutics Inc. COMPOSITIONS AND METHODS FOR DELIVERING A NUCLEOBASE EDITING SYSTEM
WO2021119225A1 (en) * 2019-12-10 2021-06-17 Homodeus, Inc. Recombinase discovery
KR20230053735A (ko) 2020-03-04 2023-04-21 플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 게놈의 조정을 위한 개선된 방법 및 조성물
CN116209756A (zh) 2020-03-04 2023-06-02 旗舰先锋创新Vi有限责任公司 调控基因组的方法和组合物
JP2023535632A (ja) 2020-07-27 2023-08-18 アンジャリウム バイオサイエンシズ エージー Dna分子の組成物、その作製方法、及びその使用方法
AU2022343268A1 (en) 2021-09-08 2024-03-28 Flagship Pioneering Innovations Vi, Llc Methods and compositions for modulating a genome
CA3231712A1 (en) 2021-09-08 2023-03-16 Flagship Pioneering Innovations Vi, Llc Pah-modulating compositions and methods
JP2024535618A (ja) * 2021-10-14 2024-09-30 アシモフ,インコーポレーテッド インテグラーゼ、ランディングパッド構造、およびそれを含む操作された細胞
WO2023081762A2 (en) * 2021-11-03 2023-05-11 The Regents Of The University Of California Serine recombinases
WO2023108153A2 (en) 2021-12-10 2023-06-15 Flagship Pioneering Innovations Vi, Llc Cftr-modulating compositions and methods
EP4448742A1 (en) * 2021-12-17 2024-10-23 Massachusetts Institute Of Technology Programmable insertion approaches via reverse transcriptase recruitment
EP4602156A2 (en) * 2022-10-11 2025-08-20 The Trustees of Columbia University in the City of New York Compositions, methods, and systems for dna modification
EP4652288A2 (en) * 2023-01-18 2025-11-26 Fred Hutchinson Cancer Center Viral particle producer cells with landing pad-integrated viral vectors
EP4704920A1 (en) * 2023-05-04 2026-03-11 Abeona Therapeutics Inc. Recombinant adeno-associated viral vectors for multipartite gene delivery and stargardt disease treatment
CN121693564A (zh) * 2023-06-26 2026-03-17 夏威夷大学 进化的整合酶和其用于基因组编辑的方法
WO2025153769A1 (en) * 2024-01-17 2025-07-24 Orion Corporation Method

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8304233B2 (en) * 2002-06-04 2012-11-06 Poetic Genetics, Llc Methods of unidirectional, site-specific integration into a genome, compositions and kits for practicing the same
FR2850668B1 (fr) * 2003-01-31 2005-04-08 Centre Nat Rech Scient Elements genetiques mobiles appartenant a la famille mariner chez les eucaryotes hydrothermaux
US9034650B2 (en) * 2005-02-02 2015-05-19 Intrexon Corporation Site-specific serine recombinases and methods of their use
WO2008100424A2 (en) * 2007-02-09 2008-08-21 University Of Hawaii Animals and cells with genomic target sites for transposase-mediated transgenesis
EP2527448A1 (en) * 2011-05-23 2012-11-28 Novozymes A/S Simultaneous site-specific integrations of multiple gene-copies in filamentous fungi
JP7759311B2 (ja) * 2019-07-19 2025-10-23 フラッグシップ パイオニアリング イノベーションズ シックス,エルエルシー リコンビナーゼ組成物及び使用方法

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