JP2023500672A5 - - Google Patents
Info
- Publication number
- JP2023500672A5 JP2023500672A5 JP2022525649A JP2022525649A JP2023500672A5 JP 2023500672 A5 JP2023500672 A5 JP 2023500672A5 JP 2022525649 A JP2022525649 A JP 2022525649A JP 2022525649 A JP2022525649 A JP 2022525649A JP 2023500672 A5 JP2023500672 A5 JP 2023500672A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- polynucleotide
- nucleic acid
- acid vector
- vector according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962930486P | 2019-11-04 | 2019-11-04 | |
| US62/930,486 | 2019-11-04 | ||
| PCT/US2020/058780 WO2021091938A1 (en) | 2019-11-04 | 2020-11-04 | Cochlear outer hair cell promoters and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023500672A JP2023500672A (ja) | 2023-01-10 |
| JP2023500672A5 true JP2023500672A5 (https=) | 2023-11-10 |
Family
ID=75848059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022525649A Pending JP2023500672A (ja) | 2019-11-04 | 2020-11-04 | 蝸牛外有毛細胞プロモーター及びその使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20220288236A1 (https=) |
| EP (1) | EP4054653A4 (https=) |
| JP (1) | JP2023500672A (https=) |
| CN (1) | CN115066264A (https=) |
| WO (1) | WO2021091938A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3727468A4 (en) | 2017-12-19 | 2021-09-22 | Akouos, Inc. | AAV-MEDIATED THERAPEUTIC ANTIBODIES DELIVERY TO THE INTERNAL EAR |
| WO2020014625A1 (en) | 2018-07-13 | 2020-01-16 | Akouos, Inc. | Methods of treating non-syndromic sensorineural hearing loss |
| US20220054640A1 (en) * | 2018-12-11 | 2022-02-24 | Decibel Therapeutics, Inc. | Compositions and methods for the delivery of therapeutic agents across the round window membrane |
| IL303317A (en) | 2020-12-01 | 2023-07-01 | Akouos Inc | ANTI-NATURAL ANTIBODY STRUCTURES AND RELATED METHODS FOR THE TREATMENT OF SYMPTOMS ASSOCIATED WITH VESTIBULAR SWANNOMA |
| EP4409009A4 (en) * | 2021-09-30 | 2025-12-17 | Akouos Inc | Compositions for administering gene therapy and methods for treating hearing loss |
| CN116836975A (zh) * | 2022-03-25 | 2023-10-03 | 上海玮美基因科技有限责任公司 | 一种耳蜗和/或前庭细胞特异性启动子及其应用 |
| CN121263526A (zh) * | 2023-05-23 | 2026-01-02 | 苏州星奥拓维生物技术有限公司 | 耳蜗毛细胞特异性启动子及其用途 |
| CN119061007A (zh) * | 2023-06-02 | 2024-12-03 | 苏州星奥拓维生物技术有限公司 | 耳蜗支持细胞基因治疗和再生的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1755400A2 (en) * | 2004-06-18 | 2007-02-28 | The University Of Montana | Aav mediated gene delivery to cochlear cells |
| WO2008073303A2 (en) * | 2006-12-07 | 2008-06-19 | Switchgear Genomics | Transcriptional regulatory elements of biological pathways, tools, and methods |
| CN103119180A (zh) * | 2011-01-12 | 2013-05-22 | 森永乳业株式会社 | 产生具有免疫调节作用的乳的食物的筛选方法 |
| US20190142969A1 (en) * | 2016-04-26 | 2019-05-16 | Massachusetts Eye And Ear Infirmary | ISL1-Based Gene Therapy to Treat Hearing Loss |
| US11331373B2 (en) * | 2017-02-10 | 2022-05-17 | St. Jude Children's Research Hospital | Combination therapy for treating disorders of the ear |
| EP3762040A4 (en) * | 2018-03-05 | 2022-01-05 | Children's Medical Center Corporation | COMPOSITIONS AND METHODS OF ADMINISTRATION OF NUCLEIC ACIDS TO COCHLEAR AND VESTIBULAR CELLS |
| CN112703016B (zh) * | 2018-04-27 | 2024-11-22 | 分贝治疗公司 | 肌球蛋白15启动子及其用途 |
-
2020
- 2020-11-04 WO PCT/US2020/058780 patent/WO2021091938A1/en not_active Ceased
- 2020-11-04 EP EP20883926.6A patent/EP4054653A4/en not_active Withdrawn
- 2020-11-04 CN CN202080091076.3A patent/CN115066264A/zh active Pending
- 2020-11-04 JP JP2022525649A patent/JP2023500672A/ja active Pending
-
2022
- 2022-05-03 US US17/735,326 patent/US20220288236A1/en active Pending
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